W. B. Coley, The treatment of malignant tumors by repeated inoculations of erysipelas. With a report of ten original cases, Clin Orthop Relat Res, vol.262, pp.3-11, 1893.

M. Teng, J. Galon, W. Fridman, and M. Smyth, From mice to humans: developments in cancer immunoediting, Journal of Clinical Investigation, vol.125, issue.9, pp.3338-3346, 2015.
DOI : 10.1172/JCI80004

F. Pages, J. Galon, M. Dieu-nosjean, E. Tartour, C. Sautes-fridman et al., Immune infiltration in human tumors: a prognostic factor that should not be ignored, Oncogene, vol.173, issue.8, pp.1093-1102, 2010.
DOI : 10.1038/nrc1586

R. Kennedy and E. Celis, T cells in anti-tumor immune responses, Immunological Reviews, vol.161, issue.1, pp.129-144, 2008.
DOI : 10.1038/nbt1215

A. Bruno, A. Pagani, L. Pulze, A. Albini, K. Dallaglio et al., Orchestration of Angiogenesis by Immune Cells, Frontiers in Oncology, vol.121, issue.3, p.131, 2014.
DOI : 10.1016/j.cell.2005.02.034

B. Burkholder, R. Huang, R. Burgess, S. Luo, V. Jones et al., Tumorinduced perturbations of cytokines and immune cell networks, Biochim Biophys Acta, vol.1845, issue.2, pp.182-201, 2014.

Z. Li, J. Jiang, Z. Wang, J. Zhang, X. M. Wang et al., Endogenous Interleukin-4 Promotes Tumor Development by Increasing Tumor Cell Resistance to Apoptosis, Cancer Research, vol.68, issue.21, pp.8687-8694, 2008.
DOI : 10.1158/0008-5472.CAN-08-0449

M. Terabe, J. Park, and J. Berzofsky, Role of IL-13 in regulation of anti-tumor immunity and tumor growth, Cancer Immunology, Immunotherapy, vol.53, issue.2, pp.79-85, 2004.
DOI : 10.1007/s00262-003-0445-0

D. Adeegbe and H. Nishikawa, Natural and Induced T Regulatory Cells in Cancer, Frontiers in Immunology, vol.4, p.190, 2013.
DOI : 10.3389/fimmu.2013.00190

T. Whiteside, P. Schuler, and B. Schilling, Induced and natural regulatory T cells in human cancer, Expert Opinion on Biological Therapy, vol.155, issue.10, pp.1383-1397, 2012.
DOI : 10.1007/s00262-011-1171-7

S. Bailey, M. Nelson, R. Himes, Z. Li, S. Mehrotra et al., Th17 Cells in Cancer: The Ultimate Identity Crisis, Frontiers in Immunology, vol.115, issue.6, p.276, 2014.
DOI : 10.4161/self.2.2.15832

L. Wang, T. Yi, M. Kortylewski, D. Pardoll, D. Zeng et al., IL-17 can promote tumor growth through an IL-6???Stat3 signaling pathway, The Journal of Experimental Medicine, vol.206, issue.7, pp.1457-1464, 2009.
DOI : 10.1016/j.jhep.2008.12.033

P. Muranski, A. Boni, P. Antony, L. Cassard, K. Irvine et al., Tumor-specific Th17-polarized cells eradicate large established melanoma, Blood, vol.112, issue.2, pp.362-373, 2008.
DOI : 10.1182/blood-2007-11-120998

N. Martin-orozco, P. Muranski, Y. Chung, X. Yang, T. Yamazaki et al., T Helper 17 Cells Promote Cytotoxic T Cell Activation in Tumor Immunity, Immunity, vol.31, issue.5, pp.787-798, 2009.
DOI : 10.1016/j.immuni.2009.09.014

URL : http://doi.org/10.1016/j.immuni.2009.09.014

M. Veldhoen, C. Uyttenhove, J. Van-snick, H. Helmby, A. Westendorf et al., Transforming growth factor-?? 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9???producing subset, Nature Immunology, vol.194, issue.12, pp.1341-1346, 2008.
DOI : 10.1038/ni.1659

V. Dardalhon, A. Awasthi, H. Kwon, G. Galileos, W. Gao et al., IL-4 inhibits TGF-??-induced Foxp3+ T cells and, together with TGF-??, generates IL-9+ IL-10+ Foxp3??? effector T cells, Nature Immunology, vol.201, issue.12, pp.1347-1355, 2008.
DOI : 10.1038/ni.1677

C. Uyttenhove, R. Simpson, V. Snick, and J. , Functional and structural characterization of P40, a mouse glycoprotein with T-cell growth factor activity., Proceedings of the National Academy of Sciences, vol.85, issue.18, pp.6934-6938, 1988.
DOI : 10.1073/pnas.85.18.6934

M. Fischer, M. Bijman, D. Molin, F. Cormont, C. Uyttenhove et al., Increased serum levels of interleukin-9 correlate to negative prognostic factors in Hodgkin's lymphoma, Leukemia, vol.17, issue.12, pp.2513-2516, 2003.
DOI : 10.1038/sj.leu.2403123

W. Elyaman, E. Bradshaw, C. Uyttenhove, V. Dardalhon, A. Awasthi et al., IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells, Proceedings of the National Academy of Sciences, vol.106, issue.31, pp.12885-12890, 2009.
DOI : 10.1073/pnas.0812530106

D. Hoelzinger, A. Dominguez, P. Cohen, and S. Gendler, Inhibition of Adaptive Immunity by IL9 Can Be Disrupted to Achieve Rapid T-cell Sensitization and Rejection of Progressive Tumor Challenges, Cancer Research, vol.74, issue.23, pp.6845-6855, 2014.
DOI : 10.1158/0008-5472.CAN-14-0836

R. Purwar, C. Schlapbach, S. Xiao, H. Kang, W. Elyaman et al., Robust tumor immunity to melanoma mediated by interleukin-9???producing T cells, Nature Medicine, vol.178, issue.8, pp.1248-1253, 2012.
DOI : 10.1097/SHK.0b013e31821af669

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518666

H. Nakatsukasa, D. Zhang, T. Maruyama, H. Chen, K. Cui et al., The DNA-binding inhibitor Id3 regulates IL-9 production in CD4+ T cells, Nature Immunology, vol.513, issue.10, pp.1077-1084, 2015.
DOI : 10.1038/ni.1997

K. Eller, D. Wolf, J. Huber, M. Metz, G. Mayer et al., IL-9 Production by Regulatory T Cells Recruits Mast Cells That Are Essential for Regulatory T Cell-Induced Immune Suppression, The Journal of Immunology, vol.186, issue.1, pp.83-91, 2011.
DOI : 10.4049/jimmunol.1001183

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227733

M. Grimbaldeston, C. Chen, A. Piliponsky, M. Tsai, S. Tam et al., Mast Cell-Deficient W-sash c-kit Mutant KitW-sh/W-sh Mice as a Model for Investigating Mast Cell Biology in Vivo, The American Journal of Pathology, vol.167, issue.3, pp.835-848, 2005.
DOI : 10.1016/S0002-9440(10)62055-X

A. Abdul-wahid, M. Cydzik, A. Prodeus, M. Alwash, M. Stanojcic et al., 9 immunity accompanied by mast cell activation blocks tumor cell engraftment, International Journal of Cancer, vol.53, issue.4, pp.841-853, 2016.
DOI : 10.1002/ijc.30121

Y. Lu, S. Hong, H. Li, J. Park, B. Hong et al., Th9 cells promote antitumor immune responses in vivo, Journal of Clinical Investigation, vol.122, issue.11, pp.4160-4171, 2012.
DOI : 10.1172/JCI65459DS1

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484462

Y. Zhao, X. Chu, J. Chen, Y. Wang, S. Gao et al., Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells, Nature Communications, vol.110, p.12368, 2016.
DOI : 10.1038/ncomms12368

F. Vegran, H. Berger, R. Boidot, G. Mignot, M. Bruchard et al., The transcription factor IRF1 dictates the IL-21-dependent anticancer functions of TH9 cells, Nature Immunology, vol.153, issue.8, pp.758-766, 2014.
DOI : 10.1038/nbt.1621

J. Park, H. Li, M. Zhang, Y. Lu, B. Hong et al., Murine Th9 cells promote the survival of myeloid dendritic cells in cancer immunotherapy, Cancer Immunology, Immunotherapy, vol.311, issue.5764, pp.835-845, 2014.
DOI : 10.1007/s00262-014-1557-4

I. Kim, B. Kim, C. Koh, J. Seok, J. Park et al., Glucocorticoid-induced tumor necrosis factor receptor???related protein co-stimulation facilitates tumor regression by inducing IL-9???producing helper T cells, Nature Medicine, vol.21, issue.9, pp.1010-1017, 2015.
DOI : 10.1111/j.1365-2567.2006.02453.x

X. Xiao, X. Shi, Y. Fan, X. Zhang, M. Wu et al., GITR subverts Foxp3+ Tregs to boost Th9 immunity through regulation of histone acetylation, Nature Communications, vol.118, p.8266, 2015.
DOI : 10.1016/j.immuni.2010.07.014

Y. Fang, X. Chen, Q. Bai, C. Qin, A. Mohamud et al., IL-9 inhibits HTB-72 melanoma cell growth through upregulation of p21 and TRAIL, Journal of Surgical Oncology, vol.8, issue.8, pp.969-974, 2015.
DOI : 10.1002/jso.23930

C. Wilhelm, K. Hirota, B. Stieglitz, V. Snick, J. Tolaini et al., An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation, Nature Immunology, vol.148, issue.11, pp.1071-1077, 2011.
DOI : 10.4049/jimmunol.0801941

C. Tan, M. Aziz, J. Lovaas, B. Vistica, G. Shi et al., Antigen-Specific Th9 Cells Exhibit Uniqueness in Their Kinetics of Cytokine Production and Short Retention at the Inflammatory Site, The Journal of Immunology, vol.185, issue.11, pp.6795-6801, 2010.
DOI : 10.4049/jimmunol.1001676

A. Jager, V. Dardalhon, R. Sobel, E. Bettelli, and V. Kuchroo, Th1, Th17, and Th9 Effector Cells Induce Experimental Autoimmune Encephalomyelitis with Different Pathological Phenotypes, The Journal of Immunology, vol.183, issue.11, pp.7169-7177, 2009.
DOI : 10.4049/jimmunol.0901906

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921715

E. Schmitt, T. Germann, S. Goedert, P. Hoehn, C. Huels et al., IL- 9 production of naive CD4+ T cells depends on IL-2, is synergistically enhanced by a combination of TGF-beta and IL-4, and is inhibited by IFN-gamma, J Immunol, vol.153, issue.9, pp.3989-3996, 1994.

S. Tofukuji, M. Kuwahara, J. Suzuki, O. Ohara, T. Nakayama et al., Identification of a New Pathway for Th1 Cell Development Induced by Cooperative Stimulation with IL-4 and TGF-??, The Journal of Immunology, vol.188, issue.10, pp.4846-4857, 2012.
DOI : 10.4049/jimmunol.1103799

C. Schlapbach, A. Gehad, C. Yang, R. Watanabe, E. Guenova et al., Human TH9 cells are skin-tropic and have autocrine and paracrine proinflammatory capacity T-helper type 9 cells play a central role in the pathogenesis of respiratory epithelial adenomatoid hamartoma, Sci Transl Med Medicine, vol.6, issue.21926, pp.219-227, 2014.

Z. Ye, Q. Zhou, W. Yin, M. Yuan, W. Yang et al., T Cells in Malignant Pleural Effusion, American Journal of Respiratory and Critical Care Medicine, vol.186, issue.11, pp.1168-1179, 2012.
DOI : 10.1164/rccm.201207-1307OC

X. Bu, Q. Zhou, J. Zhang, Z. Ye, Z. Tong et al., Recruitment and Phenotypic Characteristics of Interleukin 9-Producing CD4+ T Cells in Malignant Pleural Effusion, Lung, vol.186, issue.Suppl 2, pp.385-389, 2013.
DOI : 10.1007/s00408-013-9474-4

T. Parrot, M. Allard, R. Oger, H. Benlalam, D. Raingeard-de-la-bletiere et al., double-positive T??cells, European Journal of Immunology, vol.6, issue.7, pp.1770-1782, 2016.
DOI : 10.1002/eji.201546061

URL : https://hal.archives-ouvertes.fr/inserm-01319366

X. Yang, R. Pfeiffer, W. Wheeler, M. Yeager, S. Chanock et al., mutations, International Journal of Cancer, vol.24, issue.12, pp.2912-2917, 2009.
DOI : 10.1002/ijc.24622

URL : https://hal.archives-ouvertes.fr/hal-01259225

D. Schaer, J. Murphy, and J. Wolchok, Modulation of GITR for cancer immunotherapy, Current Opinion in Immunology, vol.24, issue.2, pp.217-224, 2012.
DOI : 10.1016/j.coi.2011.12.011

S. Rosenberg and N. Restifo, Adoptive cell transfer as personalized immunotherapy for human cancer, Science, vol.348, issue.6230, pp.62-68, 2015.
DOI : 10.1126/science.aaa4967

N. Hunder, H. Wallen, J. Cao, D. Hendricks, J. Reilly et al., Treatment of Metastatic Melanoma with Autologous CD4+ T Cells against NY-ESO-1, New England Journal of Medicine, vol.358, issue.25, pp.2698-2703, 2008.
DOI : 10.1056/NEJMoa0800251

L. Apetoh, S. Ladoire, G. Coukos, and F. Ghiringhelli, Combining immunotherapy and anticancer agents: the right path to achieve cancer cure?, Annals of Oncology, vol.26, issue.9, pp.1813-1823, 2015.
DOI : 10.1093/annonc/mdv209