R. Benedito, C. Roca, I. Sö-rensen, S. Adams, A. Gossler et al., The Notch Ligands Dll4 and Jagged1 Have Opposing Effects on Angiogenesis, Cell, vol.137, issue.6, pp.1124-1135, 2009.
DOI : 10.1016/j.cell.2009.03.025
URL : http://doi.org/10.1016/j.cell.2009.03.025

M. Bignon, C. Pichol-thievend, J. Hardouin, M. Malbouyres, N. Bré-chot et al., Lysyl oxidase-like protein-2 regulates sprouting angiogenesis and type IV collagen assembly in the endothelial basement membrane, Blood, vol.118, issue.14, pp.3979-3989, 2011.
DOI : 10.1182/blood-2010-10-313296

C. Billottet, P. Rottiers, F. Tatin, C. Varon, E. Reuzeau et al., Regulatory signals for endothelial podosome formation, European Journal of Cell Biology, vol.87, issue.8-9, pp.543-554, 2008.
DOI : 10.1016/j.ejcb.2008.02.006

F. Braet and E. Wisse, Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: A review, Comp. Hepatol, vol.1, issue.1, 2002.

V. Caolo, N. M. Van-den-akker, S. Verbruggen, M. M. Donners, G. Swennen et al., Feed-forward Signaling by Membrane-bound Ligand Receptor Circuit: THE CASE OF NOTCH DELTA-LIKE 4 LIGAND IN ENDOTHELIAL CELLS, Journal of Biological Chemistry, vol.285, issue.52, pp.40681-40689, 2010.
DOI : 10.1074/jbc.M110.176065

D. Souza, B. Miyamoto, A. Weinmaster, and G. , The many facets of Notch ligands, Oncogene, vol.19, issue.38, pp.5148-5167, 2008.
DOI : 10.1002/gene.10081

T. Daubon, P. Spuul, F. Alonso, I. Fremaux, and E. Gé-not, VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells, Journal of Cell Science, vol.129, issue.13, pp.2586-2598, 2016.
DOI : 10.1242/jcs.186585

G. E. Davis and D. R. Senger, Endothelial Extracellular Matrix: Biosynthesis, Remodeling, and Functions During Vascular Morphogenesis and Neovessel Stabilization, Circulation Research, vol.97, issue.11, pp.1093-1107, 2005.
DOI : 10.1161/01.RES.0000191547.64391.e3

D. Smet, F. Segura, I. , D. Bock, K. Hohensinner et al., Mechanisms of Vessel Branching: Filopodia on Endothelial Tip Cells Lead the Way, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.29, issue.5, pp.639-649, 2009.
DOI : 10.1161/ATVBAHA.109.185165

R. Del-toro, C. Prahst, T. Mathivet, G. Siegfried, J. S. Kaminker et al., Identification and functional analysis of endothelial tip cell-enriched genes, Blood, vol.116, issue.19, pp.4025-4033, 2010.
DOI : 10.1182/blood-2010-02-270819

L. T. Edgar, C. J. Underwood, J. E. Guilkey, J. B. Hoying, and J. A. Weiss, Extracellular Matrix Density Regulates the Rate of Neovessel Growth and Branching in Sprouting Angiogenesis, PLoS ONE, vol.292, issue.1, p.85178, 2014.
DOI : 10.1371/journal.pone.0085178.s002

E. Azzouzi, K. Wiesner, C. Linder, and S. , Metalloproteinase MT1-MMP islets act as memory devices for podosome reemergence, The Journal of Cell Biology, vol.114, issue.1, pp.109-125, 2016.
DOI : 10.1083/jcb.201510043.dv

A. Fantin, A. Lampropoulou, G. Gestri, C. Raimondi, V. Senatore et al., NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells, Cell Reports, vol.11, issue.10, pp.1577-1590, 2015.
DOI : 10.1016/j.celrep.2015.05.018

M. Hellströ-m, L. K. Phng, J. J. Hofmann, E. Wallgard, L. Coultas et al., Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis, Nature, vol.25, issue.7129, pp.776-780, 2007.
DOI : 10.1038/nature05571

A. Hielscher, K. Ellis, C. Qiu, J. Porterfield, and S. Gerecht, Fibronectin Deposition Participates in Extracellular Matrix Assembly and Vascular Morphogenesis, PLOS ONE, vol.113, issue.10, 2016.
DOI : 10.1371/journal.pone.0147600.s009

J. J. Hofmann, L. Iruela-arispe, and M. , Notch expression patterns in the retina: An eye on receptor???ligand distribution during angiogenesis, Gene Expression Patterns, vol.7, issue.4, 2007.
DOI : 10.1016/j.modgep.2006.11.002

L. Jakobsson, C. A. Franco, K. Bentley, R. T. Collins, B. Ponsioen et al., Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting, Nature Cell Biology, vol.174, issue.10, pp.943-953, 2010.
DOI : 10.1038/ncb2103

B. Jiang, G. I. Liou, M. A. Behzadian, C. , and R. B. , Astrocytes modulate retinal vasculogenesis: Effects on fibronectin expression, J. Cell Sci, vol.107, pp.2499-2508, 1994.
DOI : 10.1002/glia.440150102

A. Juin, E. Planus, F. Guillemot, P. Horakova, C. Albiges-rizo et al., Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells, Biology of the Cell, vol.49, issue.1, pp.46-57, 2013.
DOI : 10.1111/boc.201200037

P. Kouklis, M. Konstantoulaki, and A. B. Malik, VE-cadherin-induced Cdc42 Signaling Regulates Formation of Membrane Protrusions in Endothelial Cells, Journal of Biological Chemistry, vol.278, issue.18, pp.16230-16236, 2003.
DOI : 10.1074/jbc.M212591200

A. Labernadie, A. Bouissou, P. Delobelle, S. Balor, R. Voituriez et al., Protrusion force microscopy reveals oscillatory force generation and mechanosensing activity of human macrophage podosomes, Nature Communications, vol.43, p.5343, 2014.
DOI : 10.1016/S0006-3495(83)84410-5

L. Lamalice, F. Houle, G. Jourdan, and J. Huot, Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38, Oncogene, vol.23, issue.2, pp.434-445, 2004.
DOI : 10.1038/sj.onc.1207034

S. Linder, The matrix corroded: podosomes and invadopodia in extracellular matrix degradation, Trends in Cell Biology, vol.17, issue.3, pp.107-117, 2007.
DOI : 10.1016/j.tcb.2007.01.002

S. Linder and C. Wiesner, Tools of the trade: podosomes as multipurpose organelles of monocytic cells, Cellular and Molecular Life Sciences, vol.187, issue.7, pp.121-135, 2015.
DOI : 10.1007/s00018-014-1731-z

I. B. Lobov, R. A. Renard, N. Papadopoulos, N. W. Gale, G. Thurston et al., Delta-like ligand 4 (Dll4) is induced by VEGF as a negative regulator of angiogenic sprouting, Proc. Natl. Acad. Sci. USA, pp.3219-3224, 2007.
DOI : 10.1073/pnas.0611206104

S. Lowell and F. M. Watt, Delta regulates keratinocyte spreading and motility independently of differentiation, Mechanisms of Development, vol.107, issue.1-2, pp.133-140, 2001.
DOI : 10.1016/S0925-4773(01)00459-2

E. Mizuhara, T. Nakatani, Y. Minaki, Y. Sakamoto, Y. Ono et al., MAGI1 Recruits Dll1 to Cadherin-based Adherens Junctions and Stabilizes It on the Cell Surface, Journal of Biological Chemistry, vol.280, issue.28, pp.26499-26507, 2005.
DOI : 10.1074/jbc.M500375200

S. C. Mueller, C. , and W. T. , Cellular invasion into matrix beads: Localization of beta 1 integrins and fibronectin to the invadopodia, J. Cell Sci, vol.99, pp.213-225, 1991.

A. E. Osiak, G. Zenner, and S. Linder, Subconfluent endothelial cells form podosomes downstream of cytokine and RhoGTPase signaling, Experimental Cell Research, vol.307, issue.2, 2005.
DOI : 10.1016/j.yexcr.2005.03.035

A. Pintar, A. De-biasio, M. Popovic, N. Ivanova, and S. Pongor, The intracellular region of Notch ligands: does the tail make the difference?, Biology Direct, vol.2, issue.1, 2007.
DOI : 10.1186/1745-6150-2-19

M. Potente, H. Gerhardt, C. , and P. , Basic and Therapeutic Aspects of Angiogenesis, Cell, vol.146, issue.6, pp.873-887, 2011.
DOI : 10.1016/j.cell.2011.08.039

L. Redmond and A. Ghosh, The role of Notch and Rho GTPase signaling in the control of dendritic development, Current Opinion in Neurobiology, vol.11, issue.1, pp.111-117, 2001.
DOI : 10.1016/S0959-4388(00)00181-1

A. G. Remacle, V. S. Golubkov, S. A. Shiryaev, R. Dahl, J. L. Stebbins et al., Novel MT1-MMP Small-Molecule Inhibitors Based on Insights into Hemopexin Domain Function in Tumor Growth, Cancer Research, vol.72, issue.9, pp.2339-2349, 2012.
DOI : 10.1158/0008-5472.CAN-11-4149

J. Riedl, K. C. Flynn, A. Raducanu, F. Gä-rtner, G. Beck et al., Lifeact mice for studying F-actin dynamics, Nature Methods, vol.108, issue.3, pp.168-169, 2010.
DOI : 10.1038/nmeth0310-168
URL : http://hdl.handle.net/11858/00-001M-0000-0012-1FE8-8

P. Rottiers, F. Saltel, T. Daubon, B. Chaigne-delalande, V. Tridon et al., TGFbeta-induced endothelial podosomes mediate basement membrane collagen degradation in arterial vessels, 2009.
DOI : 10.1242/jcs.057448
URL : http://jcs.biologists.org/cgi/content/short/122/23/4311

R. G. Rowe and S. J. Weiss, Breaching the basement membrane: who, when and how?, Trends in Cell Biology, vol.18, issue.11, pp.560-574, 2008.
DOI : 10.1016/j.tcb.2008.08.007

R. C. Sainson, J. Aoto, M. N. Nakatsu, M. Holderfield, E. Conn et al., Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis, The FASEB Journal, vol.19, pp.1027-1029, 2005.
DOI : 10.1096/fj.04-3172fje

M. Santiago-medina, K. A. Gregus, R. H. Nichol, S. M. O-'toole, and T. M. Gomez, Regulation of ECM degradation and axon guidance by growth cone invadosomes, Development, vol.142, issue.3, pp.486-496, 2015.
DOI : 10.1242/dev.108266

G. Seano, G. Chiaverina, P. A. Gagliardi, L. Di-blasio, A. Puliafito et al., Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis, Nature Cell Biology, vol.152, issue.10, pp.931-941, 2014.
DOI : 10.1158/0008-5472.CAN-04-2691
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564017

H. Sheldon, E. Heikamp, H. Turley, R. Dragovic, P. Thomas et al., New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes, Blood, vol.116, issue.13, pp.2385-2394, 2010.
DOI : 10.1182/blood-2009-08-239228

J. R. Shutter, S. Scully, W. Fan, W. G. Richards, J. Kitajewski et al., Dll4, a novel Notch ligand expressed in arterial endothelium, Genes Dev, vol.14, pp.1313-1318, 2000.

A. F. Siekmann, L. Covassin, L. , and N. D. , Modulation of VEGF signalling output by the Notch pathway, BioEssays, vol.7, issue.4, pp.303-313, 2008.
DOI : 10.1002/bies.20736

P. Spuul, P. Ciufici, V. Veillat, A. Leclercq, T. Daubon et al., Importance of RhoGTPases in formation, characteristics, and functions of invadosomes, Small GTPases, vol.99, issue.2, 2014.
DOI : 10.4049/jimmunol.0802096

P. Spuul, P. Y. Chi, C. Billottet, C. F. Chou, and E. Gé-not, Microfluidic devices for the study of actin cytoskeleton in constricted environments: Evidence for podosome formation in endothelial cells exposed to a confined slit, Methods, vol.94, pp.65-74, 2016.
DOI : 10.1016/j.ymeth.2015.09.001

D. Stenzel, C. A. Franco, S. Estrach, A. Mettouchi, D. Sauvaget et al., Endothelial basement membrane limits tip cell formation by inducing Dll4/Notch signalling in vivo, EMBO reports, vol.220, issue.11, pp.1135-1143, 2011.
DOI : 10.1158/0008-5472.CAN-04-0291

G. A. Strasser, J. S. Kaminker, and M. Tessier-lavigne, Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching, Blood, vol.115, issue.24, pp.5102-5110, 2010.
DOI : 10.1182/blood-2009-07-230284

S. Suchting, C. Freitas, F. Le-noble, R. Benedito, C. Bré-ant et al., The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching, Proc. Natl. Acad. Sci. USA, pp.3225-3230, 2007.
DOI : 10.1073/pnas.0611177104
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805603

L. Taylor, K. Arner, K. Engelsberg, and F. Ghosh, Scaffolding the retina: The interstitial extracellular matrix during rat retinal development, International Journal of Developmental Neuroscience, vol.42, 2015.
DOI : 10.1016/j.ijdevneu.2015.03.002

T. Tojima, J. H. Hines, J. R. Henley, and H. Kamiguchi, Second messengers and membrane trafficking direct and organize growth cone steering, Nature Reviews Neuroscience, vol.104, issue.4, 2011.
DOI : 10.1038/nrn2996
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133775

K. Van-den-dries, M. B. Meddens, S. De-keijzer, S. Shekhar, V. Subramaniam et al., Interplay between myosin IIA-mediated contractility and actin network integrity orchestrates podosome composition and oscillations, Nature Communications, vol.375, 1412.
DOI : 10.1038/ncomms2402

E. Van-goethem, R. Guiet, S. Balor, G. M. Charriè-re, R. Poincloux et al., Macrophage podosomes go 3D, European Journal of Cell Biology, vol.90, issue.2-3, pp.224-236, 2011.
DOI : 10.1016/j.ejcb.2010.07.011

V. W. Van-hinsbergh and P. Koolwijk, Endothelial sprouting and angiogenesis: matrix metalloproteinases in the lead, Cardiovascular Research, vol.78, issue.2, pp.203-212, 2008.
DOI : 10.1093/cvr/cvm102

S. Sauze, E. Reuzeau, I. Kramer, and E. Gé-not, Transforming growth factor beta induces rosettes of podosomes in primary aortic endothelial cells, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00322039

. Podosomes, Multipurpose organelles?, Int. J. Biochem. Cell Biol, vol.65, pp.52-60

A. Wacker, G. , and H. , Endothelial development taking shape, Current Opinion in Cell Biology, vol.23, pp.676-685, 2011.
DOI : 10.1016/j.ceb.2011.10.002

J. Wang, Y. Taba, J. Pang, G. Yin, C. Yan et al., GIT1 Mediates VEGF-Induced Podosome Formation in Endothelial Cells: Critical Role for PLC??, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.29, issue.2, pp.202-208, 2009.
DOI : 10.1161/ATVBAHA.108.174391
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735351

C. Wiesner, J. Faix, M. Himmel, F. Bentzien, and S. Linder, KIF5B and KIF3A/KIF3B kinesins drive MT1-MMP surface exposure, CD44 shedding, and extracellular matrix degradation in primary macrophages, Blood, vol.116, issue.9, pp.1559-1569, 2010.
DOI : 10.1182/blood-2009-12-257089

I. Yana, H. Sagara, S. Takaki, K. Takatsu, K. Nakamura et al., Crosstalk between neovessels and mural cells directs the site-specific expression of MT1-MMP to endothelial tip cells, Journal of Cell Science, vol.120, issue.9, pp.1607-1614, 2007.
DOI : 10.1242/jcs.000679

P. D. Yurchenco, P. S. Amenta, and B. L. Patton, Basement membrane assembly, stability and activities observed through a developmental lens, Matrix Biology, vol.22, issue.7, pp.521-538, 2004.
DOI : 10.1016/j.matbio.2003.10.006