H. Azukizawa, H. Kosaka, S. Sano, W. R. Heath, I. Takahashi et al., Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes, European Journal of Immunology, vol.33, issue.7, pp.1879-1888, 2003.
DOI : 10.1002/eji.200323630

N. Homeostatic, Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance, Immunity, vol.42, pp.627-639

S. P. Berzins, F. W. Mcnab, C. M. Jones, M. J. Smyth, G. et al., Long-term retention of mature NK1, 1+ NKT cells in the thymus, 2006.

V. R. Buchholz, T. N. Schumacher, and D. H. Busch, T Cell Fate at the Single-Cell Level, Annual Review of Immunology, vol.34, issue.1, pp.65-92, 2016.
DOI : 10.1146/annurev-immunol-032414-112014

K. Crozat, S. Tamoutounour, T. P. Vu-manh, E. Fossum, H. Luche et al., Cutting Edge: Expression of XCR1 Defines Mouse Lymphoid-Tissue Resident and Migratory Dendritic Cells of the CD8??+ Type, The Journal of Immunology, vol.187, issue.9, pp.4411-4415, 2011.
DOI : 10.4049/jimmunol.1101717

URL : https://hal.archives-ouvertes.fr/hal-00672203

A. N. Desch, S. L. Gibbings, E. T. Clambey, W. J. Janssen, J. E. Slansky et al., Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction, Nature Communications, vol.595, p.4674, 2014.
DOI : 10.1038/ni1008-1091

K. G. Elpek, A. Bellemare-pelletier, D. Malhotra, E. D. Reynoso, V. Lukacs-kornek et al., Lymphoid Organ-Resident Dendritic Cells Exhibit Unique Transcriptional Fingerprints Based on Subset and Site, PLoS ONE, vol.9, issue.8, 2011.
DOI : 10.1371/journal.pone.0023921.s007

L. M. Francisco, V. H. Salinas, K. E. Brown, V. K. Vanguri, G. J. Freeman et al., PD-L1 regulates the development, maintenance, and function of induced regulatory T cells, The Journal of Experimental Medicine, vol.63, issue.13, pp.3015-3029, 2009.
DOI : 10.1016/j.molimm.2007.08.013

M. Guilliams, K. Crozat, S. Henri, S. Tamoutounour, P. Grenot et al., Skin-draining lymph nodes contain dermis-derived CD103- dendritic cells that constitutively produce retinoic acid and induce Foxp3+ regulatory T cells, Blood, vol.115, issue.10, 1958.
DOI : 10.1182/blood-2009-09-245274

URL : https://hal.archives-ouvertes.fr/hal-00502990

S. Henri, L. F. Poulin, S. Tamoutounour, L. Ardouin, M. Guilliams et al., CD207+ CD103+ dermal dendritic cells cross-present keratinocytederived antigens irrespective of the presence of Langerhans cells, J. Exp, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00502774

K. Hochweller, G. H. Wabnitz, Y. Samstag, J. Suffner, G. J. Hä-mmerling et al., Dendritic cells control T cell tonic signaling required for responsiveness to foreign antigen, Proc. Natl. Acad. Sci. USA, pp.5931-5936, 2010.
DOI : 10.1073/pnas.0911877107

M. Irla, S. Hugues, J. Gill, T. Nitta, Y. Hikosaka et al., Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity, Immunity, vol.29, issue.3, pp.451-463, 2008.
DOI : 10.1016/j.immuni.2008.08.007

. Irizarry, Quality control of the array hybridization and normalization of the raw Affymetrix expression data with Robust Multi-chip Analysis were performed through Bioconductor in the R statistical environment (version 3.0.2), using for the GeneChip Mouse Gene 1, Affymetrix Gene Chip Operating System to generate .cel files ST platform the oligo package and for the GeneChip Mouse Genome 430 2.0 platform the affy, affyPLM and yaqcaffy packages

P. Agarwal, A. Raghavan, S. L. Nandiwada, J. M. Curtsinger, P. R. Bohjanen et al., Gene Regulation and Chromatin Remodeling by IL-12 and Type I IFN in Programming for CD8 T Cell Effector Function and Memory, The Journal of Immunology, vol.183, issue.3, pp.1695-1704, 2009.
DOI : 10.4049/jimmunol.0900592

M. Okabe, K. Yoshikawa, and S. Itami, Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes, Eur J Immunol, vol.33, pp.1879-1888, 2003.

M. Bajenoff, S. Granjeaud, and S. Guerder, The Strategy of T Cell Antigen-presenting Cell Encounter in Antigen-draining Lymph Nodes Revealed by Imaging of Initial T Cell Activation, The Journal of Experimental Medicine, vol.17, issue.5, 2003.
DOI : 10.1126/science.2648569

T. Baranek, T. P. Manh, Y. Alexandre, M. A. Maqbool, J. Z. Cabeza et al., Differential Responses of Immune Cells to Type I Interferon Contribute to Host Resistance to Viral Infection, Cell Host & Microbe, vol.12, issue.4, pp.571-584, 2012.
DOI : 10.1016/j.chom.2012.09.002

M. J. Barnden, J. Allison, W. R. Heath, and F. R. Carbone, Defective TCR expression in transgenic mice constructed using cDNA-based alpha- and beta-chain genes under the control of heterologous regulatory elements, Immunology and Cell Biology, vol.263, issue.1, pp.34-40, 1998.
DOI : 10.1084/jem.176.6.1733

S. Bedoui, W. R. Heath, and S. N. Mueller, T-cell immunity, Immunological Reviews, vol.5, issue.1, pp.52-64, 2016.
DOI : 10.1111/imr.12426

B. M. Bolstad, R. A. Irizarry, M. Astrand, and T. P. Speed, A comparison of normalization methods for high density oligonucleotide array data based on variance and bias, Bioinformatics, vol.19, issue.2, pp.185-193, 2003.
DOI : 10.1093/bioinformatics/19.2.185

M. Drumea-mirancea, J. T. Wessels, C. A. Muller, M. Essl, J. A. Eble et al., Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules, Journal of Cell Science, vol.119, issue.7, pp.1396-1405, 2006.
DOI : 10.1242/jcs.02840

S. Eickhoff, A. Brewitz, M. Y. Gerner, F. Klauschen, K. Komander et al., Robust Anti-viral Immunity Requires Multiple Distinct T Cell-Dendritic Cell Interactions, Cell, vol.162, issue.6, pp.1322-1337, 2015.
DOI : 10.1016/j.cell.2015.08.004

M. Greyer, P. G. Whitney, A. T. Stock, G. M. Davey, C. Tebartz et al., T Cell Help Amplifies Innate Signals in CD8 + DCs for Optimal CD8 + T Cell Priming, Cell Help Amplifies Innate Signals in CD8(+) DCs for Optimal CD8(+) T Cell Priming, pp.586-597, 2016.
DOI : 10.1016/j.celrep.2015.12.058

R. A. Irizarry, B. Hobbs, F. Collin, Y. D. Beazer-barclay, K. J. Antonellis et al., Exploration, normalization, and summaries of high density oligonucleotide array probe level data, Biostatistics, vol.4, issue.2, pp.249-264, 2003.
DOI : 10.1093/biostatistics/4.2.249

T. A. Kadlecek, N. S. Van-oers, L. Lefrancois, S. Olson, D. Finlay et al., Differential requirements for ZAP-70 in TCR signaling and T cell development, J Immunol, vol.161, pp.4688-4694, 1998.

A. Kissenpfennig, S. Henri, B. Dubois, C. Laplace-builhe, P. Perrin et al., Dynamics and Function of Langerhans Cells In Vivo, Immunity, vol.22, issue.5, pp.643-654, 2005.
DOI : 10.1016/j.immuni.2005.04.004

URL : https://hal.archives-ouvertes.fr/hal-00165695

B. R. Ludviksson, R. O. Ehrhardt, and W. Strober, Role of IL-12 in intrathymic negative selection, J Immunol, vol.163, pp.4349-4359, 1999.

L. Madsen, N. Labrecque, J. Engberg, A. Dierich, A. Svejgaard et al., Mice lacking all conventional MHC class II genes, Proceedings of the National Academy of Sciences, vol.96, issue.18, pp.10338-10343, 1999.
DOI : 10.1073/pnas.96.18.10338

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC17889

Y. Maeda, H. Nishikawa, D. Sugiyama, D. Ha, M. Hamaguchi et al., Detection of self-reactive CD8+ T cells with an anergic phenotype in healthy individuals, Science, vol.346, issue.6216, pp.1536-1540, 2014.
DOI : 10.1126/science.aaa1292

T. P. Manh, Y. Alexandre, T. Baranek, K. Crozat, and M. Dalod, Plasmacytoid, conventional, and monocyte-derived dendritic cells undergo a profound and convergent genetic reprogramming during their maturation, European Journal of Immunology, vol.13, issue.7, pp.1706-1715, 2013.
DOI : 10.1002/eji.201243106

M. Mashayekhi, M. M. Sandau, I. R. Dunay, E. M. Frickel, A. Khan et al., CD8??+ Dendritic Cells Are the Critical Source of Interleukin-12 that Controls Acute Infection by Toxoplasma gondii Tachyzoites, Immunity, vol.35, issue.2, pp.249-259, 2011.
DOI : 10.1016/j.immuni.2011.08.008

U. Muller, U. Steinhoff, L. F. Reis, S. Hemmi, J. Pavlovic et al., Functional role of type I and type II interferons in antiviral defense, Science, vol.264, issue.5167, 1918.
DOI : 10.1126/science.8009221

R. T. Palframan, S. Jung, G. Cheng, W. Weninger, Y. Luo et al., Inflammatory Chemokine Transport and Presentation in HEV, The Journal of Experimental Medicine, vol.91, issue.9, pp.1361-1373, 2001.
DOI : 10.1111/j.1600-065X.1997.tb00955.x

H. C. Probst, S. Muth, and H. Schild, Regulation of the tolerogenic function of steady-state DCs, European Journal of Immunology, vol.458, issue.4, pp.927-933, 2014.
DOI : 10.1002/eji.201343862

R. L. Reinhardt, S. Hong, S. J. Kang, Z. E. Wang, and R. M. Locksley, Visualization of IL-12/23p40 In Vivo Reveals Immunostimulatory Dendritic Cell Migrants that Promote Th1 Differentiation, The Journal of Immunology, vol.177, issue.3, pp.1618-1627, 2006.
DOI : 10.4049/jimmunol.177.3.1618

S. H. Robbins, T. Walzer, D. Dembele, C. Thibault, A. Defays et al., Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling, Genome Biology, vol.9, issue.1, p.17, 2008.
DOI : 10.1186/gb-2008-9-1-r17

URL : https://hal.archives-ouvertes.fr/hal-00282558

Y. Shinkai, G. Rathbun, K. P. Lam, E. M. Oltz, V. Stewart et al., RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement, Cell, vol.68, issue.5, pp.855-867, 1992.
DOI : 10.1016/0092-8674(92)90029-C

A. Subramanian, H. Kuehn, J. Gould, P. Tamayo, and J. P. Mesirov, GSEA-P: a desktop application for Gene Set Enrichment Analysis, Bioinformatics, vol.23, issue.23, pp.3251-3253, 2007.
DOI : 10.1093/bioinformatics/btm369

S. S. Sung, S. M. Fu, C. E. Rose, . Jr, F. Gaskin et al., A Major Lung CD103 (??E)-??7 Integrin-Positive Epithelial Dendritic Cell Population Expressing Langerin and Tight Junction Proteins, The Journal of Immunology, vol.176, issue.4, pp.2161-2172, 2006.
DOI : 10.4049/jimmunol.176.4.2161

S. Tamoutounour, S. Henri, H. Lelouard, B. De-bovis, C. De-haar et al., CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis, European Journal of Immunology, vol.158, issue.12, pp.3150-3166, 2012.
DOI : 10.1002/eji.201242847

D. Terhorst, E. Fossum, A. Baranska, S. Tamoutounour, C. Malosse et al., Dendritic Cells Induces Potent Antitumoral Responses, The Journal of Immunology, vol.194, issue.12, pp.5895-5902, 2015.
DOI : 10.4049/jimmunol.1500564

S. Vandenabeele, H. Hochrein, N. Mavaddat, K. Winkel, and K. Shortman, Human thymus contains 2 distinct dendritic cell populations, Blood, vol.97, issue.6, pp.1733-1741, 2001.
DOI : 10.1182/blood.V97.6.1733