M. Scid, severe combined immunodeficient; OncomiR: oncogenic microRNA; PCR: polymerase chain reaction ERK1/2 phosphorylated form; PRO: prodomain; RIN: RNA integrity number; RT: reverse transcriptase; RT-qPCR: quantitative reverse transcription polymerase chain reaction; shA8-20: a stable clone of MDA-MB- 231 cells expressing ADAM8 shRNA; shCtrl-3: control short hairpin RNA; shRNA: short hairpin RNA; siCtrl: non-silencing control siRNA; siRNAs: short interfering RNAs; TNBC: triple-negative breast cancer; WCE: whole cell extract

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