The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher.

Adam Chodobski 1 Jean-François Ghersi-Egea 2 Charles Nicholson 3 Tavarekere Nagaraja 4 Joanna Szmydynger-Chodobska 1, *
* Auteur correspondant
1 Neurotrauma and Brain Barriers Research Laboratory
2 CRNL - Centre de recherche en neurosciences de Lyon
3 Department of Physiology and Neuroscience
4 Department of Anesthesiology
Abstract : In June 2014 Dr. Joseph D. Fenstermacher celebrated his 80th birthday, which was honored by the symposium held in New London, NH, USA. This review discusses Fenstermacher's contribution to the field of fluids and barriers of the CNS. Specifically, his fundamental work on diffusion of molecules within the brain extracellular space and the research on properties of the blood-brain barrier in health and disease are described. Fenstermacher's early research on cerebrospinal fluid dynamics and the regulation of cerebral blood flow is also reviewed, followed by the discussion of his more recent work involving the use of magnetic resonance imaging.
Keywords : Tumour therapy Cerebral blood flow MRI contrast agent Cerebrospinal fluid Brain extracellular space Ventriculocisternal perfusion Diffusion Radiolabelled tracers
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Article dans une revue
Fluids and Barriers of the CNS, BioMed Central, 2014, 12 (1), pp.1. 〈10.1186/2045-8118-12-1〉
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Adam Chodobski, Jean-François Ghersi-Egea, Charles Nicholson, Tavarekere Nagaraja, Joanna Szmydynger-Chodobska. The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher.. Fluids and Barriers of the CNS, BioMed Central, 2014, 12 (1), pp.1. 〈10.1186/2045-8118-12-1〉. 〈inserm-01264512〉

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