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Surgical treatment of bronchial asthma by resection of the laryngeal nerve

Abstract : AbstractBackgroundManagement of asthma in chronically affected patients is a serious health problem. Our aim was to show that surgical treatment of chronic bronchial asthma by unilateral resection of the internal branch of the superior laryngeal nerve (ib-SLN) is an adequateand lasting remedial response.Patients and methodsIn a retrospective study, 41 (26 male and 15 female) patients with bronchial chronic asthma were treated surgically during the period between 2005 and 2013. It consisted of a unilateral resection of the ib-SLN under optical zoom, on patients placed in supinator position. 35 patients (24 male and 11 female) who were un-operated were included as a control.ResultsIn all patients, medication was reduced progressively. When the results were compared with the control group, it was seen that in 26 % of the patients, both forced expiratory volume (FEV) and peak expiratory flow (PEF) increased significantly (p <05) and only modestly in 53.6 % of patients (FEV, p <05 and PEF, p <05). In the remaining 20 % of patients, these parameters remained however unchanged. Overall, in 80 % of patients unilateral resection of the ib-SLN gave satisfactory results because it shortened the intervals and duration of asthmatic attacks, rendering thereby a reduction in medication.ConclusionThis minimal-invasive method helped prevent/cure asphyxias in chronic bronchial asthma without affecting cough reflex,respiratory control and phonation and it helped patients avoid severe crisis. This approach is of interest for patients with severe and/or uncontrolled bronchial asthma in settings with limited access to drug treatment.
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Submitted on : Friday, January 29, 2016 - 12:42:43 PM
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Ubaidullo Kurbon, Hamza Dodariyon, Abdumalik Davlatov, Sitora Janobilova, Amu Therwath, et al.. Surgical treatment of bronchial asthma by resection of the laryngeal nerve. BMC Surgery, BioMed Central, 2015, 15 (1), pp.109. ⟨10.1186/s12893-015-0093-2⟩. ⟨inserm-01264486⟩



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