Skip to Main content Skip to Navigation
Journal articles

Subversion of the B-cell compartment during parasitic, bacterial, and viral infections

Abstract : AbstractRecent studies on HIV infection have identified new human B-cell subsets with a potentially important impact on anti-viral immunity. Current work highlights the occurrence of similar B-cell alterations in other viral, bacterial, and parasitic infections, suggesting that common strategies have been developed by pathogens to counteract protective immunity. For this review, we have selected key examples of human infections for which B-cell alterations have been described, to highlight the similarities and differences in the immune responses to a variety of pathogens. We believe that further comparisons between these models will lead to critical progress in the understanding of B-cell mechanisms and will open new target avenues for therapeutic interventions.
Document type :
Journal articles
Complete list of metadatas

Cited literature [95 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-01264478
Contributor : Bmc Bmc <>
Submitted on : Friday, January 29, 2016 - 12:42:31 PM
Last modification on : Thursday, April 9, 2020 - 11:57:05 AM
Long-term archiving on: : Friday, November 11, 2016 - 8:32:24 PM

File

12865_2015_Article_79.pdf
Publication funded by an institution

Identifiers

Collections

Citation

Gwenoline Borhis, Yolande Richard. Subversion of the B-cell compartment during parasitic, bacterial, and viral infections. BMC Immunology, BioMed Central, 2015, 16 (1), pp.15. ⟨10.1186/s12865-015-0079-y⟩. ⟨inserm-01264478⟩

Share

Metrics

Record views

313

Files downloads

945