Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement, Cytotherapy, vol.8, issue.4, pp.315-317, 2006. ,
DOI : 10.1080/14653240600855905
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis, Nature, vol.9, issue.7162, pp.557-563, 2007. ,
DOI : 10.1038/nature06188
PTK787/ZK 222584 inhibits tumor growth promoting mesenchymal stem cells: Kinase activity profiling as powerful tool in functional studies, Cancer Biology & Therapy, vol.8, issue.13, pp.1239-1248, 2009. ,
DOI : 10.4161/cbt.8.13.8688
Mesenchymal Stem Cells in Cancer, Stem Cell Reviews, vol.67, issue.19, pp.119-124, 2008. ,
DOI : 10.1007/s12015-008-9030-4
Mesenchymal Stem Cells Promote Formation of Colorectal Tumors in Mice, Gastroenterology, vol.141, issue.3, pp.1046-1056, 2011. ,
DOI : 10.1053/j.gastro.2011.05.045
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion, Cell, vol.121, issue.3, pp.335-348, 2005. ,
DOI : 10.1016/j.cell.2005.02.034
Mesenchymal stem cells promote growth and angiogenesis of tumors in mice, Oncogene, vol.282, issue.37, pp.4343-4354, 2013. ,
DOI : 10.1038/onc.2012.458
Human mesenchymal stem cells creating an immunosuppressive environment and promote breast cancer in mice. Sci Rep, p.2298, 2013. ,
Activation of autophagy in mesenchymal stem cells provides tumor stromal support, Carcinogenesis, vol.32, issue.7, pp.964-972, 2011. ,
DOI : 10.1093/carcin/bgr029
Serum deprivation of human marrow stromal cells (hMSCs) selects for a subpopulation of early progenitor cells with enhanced expression of OCT-4 and other embryonic genes, Blood, vol.103, issue.5, pp.1647-1652, 2004. ,
DOI : 10.1182/blood-2003-06-1967
Mesenchymal stem cells as trophic mediators, Journal of Cellular Biochemistry, vol.16, issue.5, pp.1076-1084, 2006. ,
DOI : 10.1002/jcb.20886
Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery, Leukemia, vol.8, issue.5, pp.847-856, 2006. ,
DOI : 10.1038/ncb1132
Exosomes/microvesicles as a mechanism of cell-to-cell communication, Kidney International, vol.78, issue.9, pp.838-848, 2010. ,
DOI : 10.1038/ki.2010.278
MicroRNA in Development and in the progression of Cancer, Microvesicular transfer of microRNA in tumor microenvironment, pp.327-348, 2014. ,
Comparative marker analysis of extracellular vesicles in different human cancer types, Journal of Extracellular Vesicles, vol.57, issue.1, 2013. ,
DOI : 10.3402/jev.v2i0.20424
Tumor-stroma interaction: Revealing fibroblast-secreted exosomes as potent regulators of Wntplanar cell polarity signaling in cancer metastasis. Cancer research, pp.6843-6847, 2013. ,
in cell-fate determination, Journal of Extracellular Vesicles, vol.10, issue.16, 2013. ,
DOI : 10.3402/jev.v2i0.22390
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells, Nature Cell Biology, vol.175, issue.6, pp.654-659, 2007. ,
DOI : 10.1002/pmic.200400876
Proteomics, transcriptomics and lipidomics of exosomes and ectosomes, PROTEOMICS, vol.4, issue.10-11, pp.10-111554, 2013. ,
DOI : 10.1002/pmic.201200329
Isolation and Characterization of Exosomes from Cell Culture Supernatants and Biological Fluids, Curr Protoc Cell Biol, vol.4, p.22, 2006. ,
DOI : 10.1002/0471143030.cb0322s30
MicroRNA-34a Mediates the Autocrine Signaling of PAR2-Activating Proteinase and Its Role in Colonic Cancer Cell Proliferation, PLoS ONE, vol.55, issue.8, p.72383, 2013. ,
DOI : 10.1371/journal.pone.0072383.g007
Programmed Cell Death 4 (PDCD4) Is an Important Functional Target of the MicroRNA miR-21 in Breast Cancer Cells, Journal of Biological Chemistry, vol.283, issue.2, pp.1026-1033, 2008. ,
DOI : 10.1074/jbc.M707224200
MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer, Gastroenterology, vol.133, issue.2, pp.647-658, 2007. ,
DOI : 10.1053/j.gastro.2007.05.022
Exosomes in tumor microenvironment influence cancer progression and metastasis, Journal of Molecular Medicine, vol.18, issue.4, pp.431-437, 2013. ,
DOI : 10.1007/s00109-013-1020-6
Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts. Cancer research, pp.8492-8495, 2004. ,
Short-Term Exposure of Multipotent Stromal Cells to Low Oxygen Increases Their Expression of CX3CR1 and CXCR4 and Their Engraftment In Vivo, PLoS ONE, vol.20, issue.5, p.416, 2007. ,
DOI : 10.1371/journal.pone.0000416.s002
Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth. Cancer cell, pp.257-272, 2011. ,
Stromal cell-derived factor-1 overexpression induces gastric dysplasia through expansion of stromal myofibroblasts and epithelial progenitors, Gut, vol.62, issue.2, pp.192-200, 2013. ,
DOI : 10.1136/gutjnl-2011-301824
From The Cover: Reconstruction of functionally normal and malignant human breast tissues in mice, Proceedings of the National Academy of Sciences, vol.101, issue.14, pp.4966-4971, 2004. ,
DOI : 10.1073/pnas.0401064101
Suppression of tumor development and metastasis formation in mice lacking the S100A4(mts1) gene. Cancer research, pp.3772-3780, 2005. ,
Comparison of Metabolic Pathways between Cancer Cells and Stromal Cells in Colorectal Carcinomas: a Metabolic Survival Role for Tumor-Associated Stroma, Cancer Research, vol.66, issue.2, pp.632-637, 2006. ,
DOI : 10.1158/0008-5472.CAN-05-3260
Mutagenesis induced by the tumor microenvironment. Mutation research, pp.439-446, 1998. ,
Colony Forming Unit Assays for MSCs, Methods Mol Biol, vol.449, pp.83-91, 2008. ,
DOI : 10.1007/978-1-60327-169-1_6
Epigenetic Reprogramming of IGF1 and Leptin Genes by Serum Deprivation in Multipotential Mesenchymal Stromal Cells, Stem Cells, vol.301, issue.2, pp.375-382, 2009. ,
DOI : 10.1634/stemcells.2008-0546
Serum-deprived human multipotent mesenchymal stromal cells (MSCs) are highly angiogenic, Stem Cell Research, vol.6, issue.3, pp.215-225, 2011. ,
DOI : 10.1016/j.scr.2011.01.004
Comparative proteomics evaluation of plasma exosome isolation techniques and assessment of the stability of exosomes in normal human blood plasma, PROTEOMICS, vol.7, issue.22, pp.3354-3364, 2013. ,
DOI : 10.1002/pmic.201300282
High CD49f expression is associated with osteosarcoma tumor progression: a study using patient-derived primary cell cultures, Cancer Medicine, vol.47, issue.4, 2014. ,
DOI : 10.1002/cam4.249
Expression of metalloproteinases 2 and 9 and tissue inhibitors 1 and 2 as predictors of lymph node metastases in oropharyngeal squamous cell carcinoma. Head Neck, 2014. ,
Expression and prognostic significance of fibronectin and matrix metalloproteases in breast cancer metastasis, Histopathology, vol.12, issue.4, pp.512-522, 2014. ,
DOI : 10.1111/his.12300
The CD9/CD81 Tetraspanin Complex and Tetraspanin CD151 Regulate ??3??1 Integrin-Dependent Tumor Cell Behaviors by Overlapping but Distinct Mechanisms, PLoS ONE, vol.22, issue.4, p.61834, 2013. ,
DOI : 10.1371/journal.pone.0061834.s008
Expression of CD9 and CD82 in clear cell renal cell carcinoma and its clinical significance, Pathology - Research and Practice, vol.210, issue.5, pp.285-290, 2014. ,
DOI : 10.1016/j.prp.2014.01.004
Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor ?? Signaling, Cell, vol.157, issue.2, pp.382-394, 2014. ,
DOI : 10.1016/j.cell.2014.01.066
ExoCarta 2012: database of exosomal proteins, RNA and lipids. Nucleic acids research, pp.1241-1244, 2012. ,
Ceramide Triggers Budding of Exosome Vesicles into Multivesicular Endosomes, Science, vol.319, issue.5867, pp.1244-1247, 2008. ,
DOI : 10.1126/science.1153124
Regulation of exosome release by glycosphingolipids and flotillins, FEBS Journal, vol.10, issue.9, pp.2214-2227, 2014. ,
DOI : 10.1111/febs.12775
Thoracodorsal artery aneurysm caused by fibromuscular dysplasia, American Journal of Roentgenology, vol.149, issue.5, pp.1067-1068, 1987. ,
DOI : 10.2214/ajr.149.5.1067
Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors, NMR in Biomedicine, vol.24, issue.5, pp.1177-1186, 2012. ,
DOI : 10.1002/nbm.2787
Segregation analysis of balanced pericentric inversions in pedigree data, Clinical Genetics, vol.10, issue.Spec. Iss., pp.87-94, 1986. ,
DOI : 10.1111/j.1399-0004.1986.tb00575.x
MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation, Blood, vol.114, issue.2, pp.404-414, 2009. ,
DOI : 10.1182/blood-2008-09-179150
The miR ratio as a prognostic marker in clear cell renal cell carcinoma, Eur J Cancer, 2014. ,
Induction of miR-21 by Retinoic Acid in Estrogen Receptor-positive Breast Carcinoma Cells: BIOLOGICAL CORRELATES AND MOLECULAR TARGETS, Journal of Biological Chemistry, vol.286, issue.5, pp.4027-4042, 2011. ,
DOI : 10.1074/jbc.M110.184994
Association of microRNA-34a overexpression with proliferation is cell type-dependent, Cancer Science, vol.123, issue.12, pp.1845-1852, 2007. ,
DOI : 10.1073/pnas.0307323101
Regulation of mRNA Translation and Stability by microRNAs, Annual Review of Biochemistry, vol.79, issue.1, pp.351-379, 2010. ,
DOI : 10.1146/annurev-biochem-060308-103103
Survival in patients with metastatic recurrent breast cancer after adjuvant chemotherapy, Cancer, vol.23, issue.6, pp.1140-1148, 2013. ,
DOI : 10.1002/cncr.27819
Isolation and Expansion of Mesenchymal Stem Cells/Multipotential Stromal Cells from Human Bone Marrow, Methods Mol Biol, vol.698, pp.11-21, 2011. ,
DOI : 10.1007/978-1-60761-999-4_2
miR-7 suppresses brain metastasis of breast cancer stem-like cells by modulating KLF4. Cancer research, pp.1434-1444, 2013. ,
How pure are your vesicles? Journal of extracellular vesicles. 2013; 2. www.impactjournals.com/oncotarget Probability-based protein identification by searching sequence databases using mass spectrometry data, Electrophoresis, vol.20, issue.18, pp.3551-3567, 1999. ,
myProMS, a web server for management and validation of mass spectrometry-based proteomic data, PROTEOMICS, vol.5, issue.15, pp.2553-2556, 2007. ,
DOI : 10.1002/pmic.200600784
Sphingolipid Analysis by High Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS), Adv Exp Med Biol, vol.688, pp.46-59, 2010. ,
DOI : 10.1007/978-1-4419-6741-1_3
Analysis of mammalian sphingolipids by liquid chromatography tandem mass spectrometry (LC-MS/MS) and tissue imaging mass spectrometry (TIMS), Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1811, issue.11, pp.1811838-853, 2011. ,
DOI : 10.1016/j.bbalip.2011.06.027
"A novel in vivo model for the study of human breast cancer metastasis using primary breast tumor-initiating cells from patient biopsies", BMC Cancer, vol.11, issue.4, p.10, 2012. ,
DOI : 10.1186/bcr2349