T. Manolio, F. Collins, N. Cox, D. Goldstein, and L. Hindorff, Finding the missing heritability of complex diseases, Nature, vol.41, issue.7265, pp.747-753, 2009.
DOI : 10.1038/nature08494

C. Lill, J. Roehr, M. Mcqueen, F. Kavvoura, and S. Bagade, Comprehensive Research Synopsis and Systematic Meta-Analyses in Parkinson's Disease Genetics: The PDGene Database, PLoS Genetics, vol.40, issue.3, p.1002548, 2012.
DOI : 10.1371/journal.pgen.1002548.s007

A. Noyce, J. Bestwick, L. Silveira-moriyama, C. Hawkes, and G. Giovannoni, Meta-analysis of early nonmotor features and risk factors for Parkinson disease, Annals of Neurology, vol.120, issue.suppl 7, pp.893-901, 2012.
DOI : 10.1002/ana.23687

H. Qi and S. Li, Dose-response meta-analysis on coffee, tea and caffeine consumption with risk of Parkinson's disease, Geriatrics & Gerontology International, vol.294, issue.2, pp.1-10, 2013.
DOI : 10.1111/ggi.12123

B. Shook and P. Jackson, Receptor Antagonists and Parkinson???s Disease, ACS Chemical Neuroscience, vol.2, issue.10, pp.555-567, 2011.
DOI : 10.1021/cn2000537

P. Kraft, Y. Yen, D. Stram, J. Morrison, and W. Gauderman, Exploiting Gene-Environment Interaction to Detect Genetic Associations, Human Heredity, vol.63, issue.2, pp.111-119, 2007.
DOI : 10.1159/000099183

T. Hamza, H. Chen, E. Hill-burns, S. Rhodes, and J. Montimurro, Genome-Wide Gene-Environment Study Identifies Glutamate Receptor Gene GRIN2A as a Parkinson's Disease Modifier Gene via Interaction with Coffee, PLoS Genetics, vol.42, issue.8, p.1002237, 2011.
DOI : 10.1371/journal.pgen.1002237.s011

D. Thomas, Gene???environment-wide association studies: emerging approaches, Nature Reviews Genetics, vol.15, issue.4, pp.259-272, 2010.
DOI : 10.1038/nrg2764
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891422

D. Thomas, J. Lewinger, C. Murcray, and W. Gauderman, Invited Commentary: GE-Whiz! Ratcheting Gene-Environment Studies up to the Whole Genome and the Whole Exposome, American Journal of Epidemiology, vol.175, issue.3, pp.203-207, 2012.
DOI : 10.1093/aje/kwr365

N. Amin, E. Byrne, J. Johnson, G. Chenevix-trench, and S. Walter, Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM, Molecular Psychiatry, vol.88, issue.11, pp.1116-1129, 2012.
DOI : 10.1002/ajmg.b.30272

Q. Yang, M. Khoury, and W. Flanders, Sample Size Requirements in Case-Only Designs to Detect Gene-Environment Interaction, American Journal of Epidemiology, vol.146, issue.9, pp.713-720, 1997.
DOI : 10.1093/oxfordjournals.aje.a009346

B. Mukherjee and N. Chatterjee, Exploiting Gene-Environment Independence for Analysis of Case-Control Studies: An Empirical Bayes-Type Shrinkage Estimator to Trade-Off between Bias and Efficiency, Biometrics, vol.16, issue.6 suppl., pp.685-694, 2008.
DOI : 10.1111/j.1541-0420.2007.00953.x

L. Wermuth, C. Lassen, L. Himmerslev, J. Olsen, and B. Ritz, Validation of hospital register-based diagnosis of Parkinson's disease, Dan Med J, vol.59, p.4391, 2012.

L. Morimoto, E. White, and P. Newcomb, Selection Bias in the Assessment of Gene-Environment Interaction in Case-Control Studies, American Journal of Epidemiology, vol.158, issue.3, pp.259-263, 2003.
DOI : 10.1093/aje/kwg147

J. Witte, W. Gauderman, and D. Thomas, Asymptotic Bias and Efficiency In Case-Control Studies of Candidate Genes and Gene-Environment Interactions: Basic Family Designs, American Journal of Epidemiology, vol.149, issue.8, pp.693-705, 1999.
DOI : 10.1093/oxfordjournals.aje.a009877

Y. Wang, R. Localio, and T. Rebbeck, Evaluating Bias due to Population Stratification in Epidemiologic Studies of Gene-Gene or Gene-Environment Interactions, Cancer Epidemiology Biomarkers & Prevention, vol.15, issue.1, pp.124-156, 2006.
DOI : 10.1158/1055-9965.EPI-05-0304

C. Fayard, A. Bonaventure, I. Benatru, R. E. Dumurgier, and J. , Impact of recommendations on the initial therapy of Parkinson???s disease: A population-based study in France, Parkinsonism & Related Disorders, vol.17, issue.7, pp.543-546, 2011.
DOI : 10.1016/j.parkreldis.2011.04.020

J. Bower, D. Maraganore, S. Mcdonnell, and W. Rocca, Incidence and distribution of parkinsonism in Olmsted County, Minnesota, Neurology, vol.52, pp.1976-1990, 1999.

H. Checkoway, K. Powers, T. Smith-weller, G. Franklin, and W. Longstreth, Parkinson's Disease Risks Associated with Cigarette Smoking, Alcohol Consumption, and Caffeine Intake, American Journal of Epidemiology, vol.155, issue.8, pp.732-738, 2002.
DOI : 10.1093/aje/155.8.732
URL : http://aje.oxfordjournals.org/cgi/content/short/155/8/732

S. Searles-nielsen, H. Checkoway, R. Butler, H. Nelson, and F. Farin, LINE-1 DNA methylation, smoking and risk of Parkinson's disease, J Parkinsons Dis, vol.2, pp.303-308, 2012.

D. Maraganore, M. De-andrade, T. Lesnick, K. Strain, and M. Farrer, High-Resolution Whole-Genome Association Study of Parkinson Disease, The American Journal of Human Genetics, vol.77, issue.5, pp.685-693, 2005.
DOI : 10.1086/496902

M. Facheris, N. Schneider, T. Lesnick, M. De-andrade, and J. Cunningham, Coffee, caffeine-related genes, and Parkinson's disease: A case-control study, Movement Disorders, vol.3, issue.14, pp.2033-2040, 2008.
DOI : 10.1002/mds.22247

S. Searles-nielsen, G. Franklin, W. Longstreth, P. Swanson, and H. Checkoway, and risk of Parkinson disease, Annals of Neurology, vol.74, issue.3, pp.472-477, 2013.
DOI : 10.1002/ana.23884

W. Gauderman, Sample Size Requirements for Association Studies of Gene-Gene Interaction, American Journal of Epidemiology, vol.155, issue.5, pp.478-484, 2002.
DOI : 10.1093/aje/155.5.478

M. Huberman and B. Langholz, RE: "COMBINED ANALYSIS OF MATCHED AND UNMATCHED CASE-CONTROL STUDIES: COMPARISON OF RISK ESTIMATES FROM DIFFERENT STUDIES", American Journal of Epidemiology, vol.150, issue.2, pp.219-220, 1999.
DOI : 10.1093/oxfordjournals.aje.a009987

V. Moreno, M. Martín, F. Bosch, S. De-sanjosé, and F. Torres, Combined Analysis of Matched and Unmatched Case-Control Studies: Comparison of Risk Estimates from Different Studies, American Journal of Epidemiology, vol.143, issue.3, pp.293-300, 1996.
DOI : 10.1093/oxfordjournals.aje.a008741

L. Botto and M. Khoury, Commentary: Facing the Challenge of Gene-Environment Interaction: The Two-by-Four Table and Beyond, American Journal of Epidemiology, vol.153, issue.10, pp.1016-1020, 2001.
DOI : 10.1093/aje/153.10.1016

T. Tchetgen, E. Kraft, and P. , On the Robustness of Tests of Genetic Associations Incorporating Gene-environment Interaction When the Environmental Exposure is Misspecified, Epidemiology, vol.22, issue.2, pp.257-261, 2011.
DOI : 10.1097/EDE.0b013e31820877c5

C. Weinberg, Applicability of the simple independent action model to epidemiologic studies involving two factors and a dichotomous outcome, 1986.