Preparation and characterization of a biologic scaffold for esophageal tissue engineering
Résumé
The aim of this work is to obtain a suitable matrix for tissue engineering of the esophagus. Swine esophagi are decellularized following a new dynamic process. In vitro biocompatibility is evaluated and histological analyses and circumferential and longitudinal traction tests are performed. The results are encouraging, showing good decellularization and maintaining tissue structure, no toxicity of the final tubular matrix and mechanical properties compatible with the specifications of an esophagus substitute.
Domaines
Ingénierie biomédicale
Origine : Fichiers produits par l'(les) auteur(s)
