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Preparation and characterization of a biologic scaffold for esophageal tissue engineering

Abstract : The aim of this work is to obtain a suitable matrix for tissue engineering of the esophagus. Swine esophagi are decellularized following a new dynamic process. In vitro biocompatibility is evaluated and histological analyses and circumferential and longitudinal traction tests are performed. The results are encouraging, showing good decellularization and maintaining tissue structure, no toxicity of the final tubular matrix and mechanical properties compatible with the specifications of an esophagus substitute.
Keywords : Biomaterials
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Conference papers
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https://www.hal.inserm.fr/inserm-01154950
Contributor : Frédérique Frouin <>
Submitted on : Monday, May 25, 2015 - 6:39:49 PM
Last modification on : Tuesday, June 9, 2020 - 12:31:34 PM
Long-term archiving on: : Thursday, April 20, 2017 - 8:02:47 AM

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Guillaume Luc, Magalie Cabau, Charlotte Kaliski, Martine Renard, Sandro Cornet, et al.. Preparation and characterization of a biologic scaffold for esophageal tissue engineering. Journées RITS 2015, Mar 2015, Dourdan, France. ⟨inserm-01154950⟩

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