Performance of a standardized interrogation to improve the screening of Chlamydia trachomatis infection

Abstract : To estimate the performance of a standardized interrogation tool facilitating the detection and screening of patients for the Chlamydia trachomatis infection, to estimate the prevalence of the infection in the family planning population studied. Prospective observational study, including the patients who had a consultation in the abortion center in the CHU of Poitiers. A sampling of the cervix was systematically carried out after the standardized interrogation in search of four clinical signs. The samples were analyzed by genetic amplification. Three hundred and eighty-six women were included and 56 (14.5 %) infections were identified. The medical history questionnaire was relatively effective for 2 or 3 clinical signs. The positive predictive value (PPV) was respectively 34.8 % and 53.8 % and was very relevant for 4 clinical signs with PPV at 83.3 % [CI 95 %: 74-93 %]. Among the infected women, 48.2 % had no clinical sign revealed by the medical history questionnaire. The presence of any clinical sign was strongly associated with the C. trachomatis infection (P<0.05). The clinical signs find in the standardized interrogation are all significantly associated with the C. trachomatis infection.
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Stéphanie Grandcolin, Astrid de Hauteclocque, Anouk Lafoscade, Xavier Fritel. Performance of a standardized interrogation to improve the screening of Chlamydia trachomatis infection. Journal de Gynécologie Obstétrique et Biologie de la Reproduction, Elsevier Masson, 2014, pp.non connue à ce jour. ⟨inserm-01150253⟩

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