V. Angeli, D. Staumont, A. S. Charbonnier, H. Hammad, P. Gosset et al., Activation of the D Prostanoid Receptor 1 Regulates Immune and Skin Allergic Responses, The Journal of Immunology, vol.172, issue.6, pp.3822-3829, 2004.
DOI : 10.4049/jimmunol.172.6.3822

L. Bar-on, T. Birnberg, K. L. Lewis, B. T. Edelson, D. Bruder et al., CX3CR1+ CD8??+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells, Proceedings of the National Academy of Sciences, vol.107, issue.33, pp.14745-14750, 2010.
DOI : 10.1073/pnas.1001562107

M. Depner, M. S. Kormann, N. Klopp, T. Illig, C. Vogelberg et al., <i>CX3CR1</i> Polymorphisms Are Associated with Atopy but Not Asthma in German Children, International Archives of Allergy and Immunology, vol.144, issue.1, pp.91-94, 2007.
DOI : 10.1159/000102620

T. Echigo, M. Hasegawa, Y. Shimada, K. Takehara, and S. Sato, Expression of fractalkine and its receptor, CX3CR1, in atopic dermatitis: Possible contribution to skin inflammation, Journal of Allergy and Clinical Immunology, vol.113, issue.5, pp.940-948, 2004.
DOI : 10.1016/j.jaci.2004.02.030

A. El-shazly, P. Berger, P. O. Girodet, O. Ousova, M. Fayon et al., Fraktalkine Produced by Airway Smooth Muscle Cells Contributes to Mast Cell Recruitment in Asthma, The Journal of Immunology, vol.176, issue.3, pp.1860-1868, 2006.
DOI : 10.4049/jimmunol.176.3.1860

P. Fraticelli, M. Sironi, G. Bianchi, D. D-'ambrosio, C. Albanesi et al., Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses, Journal of Clinical Investigation, vol.107, issue.9, pp.1173-1181, 2001.
DOI : 10.1172/JCI11517

F. Geissmann, P. Revy, N. Brousse, Y. Lepelletier, C. Folli et al., Retinoids Regulate Survival and Antigen Presentation by Immature Dendritic Cells, The Journal of Experimental Medicine, vol.14, issue.4, pp.623-634, 2003.
DOI : 10.1016/0092-8674(95)90200-7

M. Grewe, C. A. Bruijnzeel-koomen, E. Schopf, T. Thepen, A. G. Langeveld-wildschut et al., A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis, Immunology Today, vol.19, issue.8, pp.359-361, 1998.
DOI : 10.1016/S0167-5699(98)01285-7

E. Guttman-yassky, K. E. Nograles, and J. G. Krueger, Contrasting pathogenesis of atopic dermatitis and psoriasis???Part I: Clinical and pathologic concepts, Journal of Allergy and Clinical Immunology, vol.127, issue.5, pp.1110-1118, 2011.
DOI : 10.1016/j.jaci.2011.01.053

E. Guttman-yassky, K. E. Nograles, and J. G. Krueger, Contrasting pathogenesis of atopic dermatitis and psoriasis???Part II: Immune cell subsets and therapeutic concepts, Journal of Allergy and Clinical Immunology, vol.127, issue.6, pp.1420-1432, 2011.
DOI : 10.1016/j.jaci.2011.01.054

J. M. Hanifin and G. Rajka, Diagnostic features of atopic dermatitis, Acta Derm Venerol, vol.92, pp.44-47, 1980.

B. Homey, H. Alenius, A. Muller, H. Soto, E. P. Bowman et al., CCL27???CCR10 interactions regulate T cell???mediated skin inflammation, Nature Medicine, vol.8, issue.2, pp.157-165, 2002.
DOI : 10.1038/nm0202-157

S. A. Islam, D. S. Chang, R. A. Colvin, M. H. Byrne, M. L. Mccully et al., Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ TH2 cells, Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells, pp.167-177, 2011.
DOI : 10.1111/j.1365-2222.2010.03504.x

V. Julia, CX3CL1 in allergic diseases: not just a chemotactic molecule, Allergy, vol.176, issue.9, pp.1106-1110, 2012.
DOI : 10.1111/j.1398-9995.2012.02870.x

S. Jung, J. Aliberti, P. Graemmel, M. J. Sunshine, G. W. Kreutzberg et al., Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion, Molecular and Cellular Biology, vol.20, issue.11, pp.4106-4114, 2000.
DOI : 10.1128/MCB.20.11.4106-4114.2000

S. Kagami, T. Kakinuma, H. Saeki, Y. Tsunemi, H. Fujita et al., Significant elevation of serum levels of eotaxin-3/CCL26, but not of eotaxin-2/CCL24, in patients with atopic dermatitis: serum eotaxin-3/CCL26 levels reflect the disease activity of atopic dermatitis, Clinical and Experimental Immunology, vol.195, issue.2, pp.309-313, 2003.
DOI : 10.1046/j.1365-2222.2001.01112.x

A. Kanda, V. Driss, N. Hornez, M. Abdallah, T. Roumier et al., Eosinophil-derived IFN-?? induces airway hyperresponsiveness and lung inflammation in the absence of lymphocytes, Journal of Allergy and Clinical Immunology, vol.124, issue.3, pp.573-582, 2009.
DOI : 10.1016/j.jaci.2009.04.031

K. W. Kim, A. Vallon-eberhard, E. Zigmond, J. Farache, E. Shezen et al., In vivo structure/function and expression analysis of the CX3C chemokine fractalkine, Blood, vol.118, issue.22, pp.156-167, 2011.
DOI : 10.1182/blood-2011-04-348946

L. Landsman, L. Bar-on, A. Zernecke, K. W. Kim, R. Krauthgamer et al., CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival, Blood, vol.113, issue.4, pp.963-972, 2009.
DOI : 10.1182/blood-2008-07-170787

N. H. Lazarus, E. J. Kunkel, B. Johnston, E. Wilson, K. R. Youngman et al., A Common Mucosal Chemokine (Mucosae-Associated Epithelial Chemokine/CCL28) Selectively Attracts IgA Plasmablasts, The Journal of Immunology, vol.170, issue.7, pp.3799-3805, 2003.
DOI : 10.4049/jimmunol.170.7.3799

D. Y. Leung, M. Boguniewicz, M. D. Howell, I. Nomura, and Q. A. Hamid, New insights into atopic dermatitis, Journal of Clinical Investigation, vol.113, issue.5, pp.651-657, 2004.
DOI : 10.1172/JCI21060

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC380238

K. J. Livak and T. D. Schmittgen, Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2???????CT Method, Methods, vol.25, issue.4, pp.402-408, 2001.
DOI : 10.1006/meth.2001.1262

O. Meucci, A. Fatatis, A. A. Simen, T. J. Bushell, P. W. Gray et al., Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity, Proceedings of the National Academy of Sciences, vol.95, issue.24, pp.14500-14505, 1998.
DOI : 10.1073/pnas.95.24.14500

Z. Mikhak, J. P. Strassner, and A. D. Luster, Lung dendritic cells imprint T cell lung homing and promote lung immunity through the chemokine receptor CCR4, The Journal of Experimental Medicine, vol.60, issue.9, pp.1855-1869, 2013.
DOI : 10.1164/rccm.200608-1068OC

C. Mionnet, V. Buatois, A. Kanda, V. Milcent, S. Fleury et al., CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung, Nature Medicine, vol.16, issue.11, pp.1305-1312, 2010.
DOI : 10.1038/nm.2253

URL : https://hal.archives-ouvertes.fr/hal-00726050

T. Nakayama, Y. Watanabe, N. Oiso, T. Higuchi, A. Shigeta et al., Eotaxin-3/CC Chemokine Ligand 26 Is a Functional Ligand for CX3CR1, The Journal of Immunology, vol.185, issue.11, pp.6472-6479, 2010.
DOI : 10.4049/jimmunol.0904126

W. Owczarek, M. Paplinska, T. Targowski, K. Jahnz-rozyk, E. Paluchowska et al., Analysis of eotaxin 1/CCL11, eotaxin 2/CCL24 and eotaxin 3/CCL26 expression in lesional and non-lesional skin of patients with atopic dermatitis, Cytokine, vol.50, issue.2, pp.181-185, 2011.
DOI : 10.1016/j.cyto.2010.02.016

M. K. Oyoshi, A. Elkhal, J. E. Scott, M. A. Wurbel, J. L. Hornick et al., Epicutaneous challenge of orally immunized mice redirects antigen-specific gut-homing T cells to the skin, Journal of Clinical Investigation, vol.121, issue.6, pp.2210-2220, 2011.
DOI : 10.1172/JCI43586DS1

Y. Reiss, A. E. Proudfoot, C. A. Power, J. J. Campbell, and E. C. Butcher, CC Chemokine Receptor (CCR)4 and the CCR10 Ligand Cutaneous T Cell???attracting Chemokine (CTACK) in Lymphocyte Trafficking to Inflamed Skin, The Journal of Experimental Medicine, vol.144, issue.10, pp.1541-1547, 2001.
DOI : 10.1084/jem.193.9.1105

T. J. Schall and A. E. Proudfoot, Overcoming hurdles in developing successful drugs targeting chemokine receptors, Nature Reviews Immunology, vol.319, issue.5, pp.355-363, 2011.
DOI : 10.1038/nri2972

J. M. Spergel, E. Mizoguchi, J. P. Brewer, T. R. Martin, A. K. Bhan et al., Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice., Journal of Clinical Investigation, vol.101, issue.8, pp.1614-1622, 1998.
DOI : 10.1172/JCI1647

J. M. Spergel, E. Mizoguchi, H. Oettgen, A. K. Bhan, and R. S. Geha, Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis, Journal of Clinical Investigation, vol.103, issue.8, pp.1103-1111, 1999.
DOI : 10.1172/JCI5669

D. Staumont-salle, G. Abboud, C. Brenuchon, A. Kanda, T. Roumier et al., Peroxisome proliferator-activated receptor ?? regulates skin inflammation and humoral response in atopic dermatitis, Journal of Allergy and Clinical Immunology, vol.121, issue.4, pp.962-968, 2008.
DOI : 10.1016/j.jaci.2007.12.1165

K. Tremblay, M. Lemire, V. Provost, T. Pastinen, Y. Renaud et al., Association study between the CX3CR1 gene and asthma, Genes and Immunity, vol.120, issue.2, pp.632-639, 2006.
DOI : 10.2307/2533494

L. Van-der-fits, S. Mourits, J. S. Voerman, M. Kant, L. Boon et al., Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis, The Journal of Immunology, vol.182, issue.9, pp.5836-5845, 2009.
DOI : 10.4049/jimmunol.0802999

Q. Wang, L. Malherbe, D. Zhang, K. Zingler, N. Glaichenhaus et al., CD4 Promotes Breadth in the TCR Repertoire, The Journal of Immunology, vol.167, issue.8, pp.4311-4320, 2001.
DOI : 10.4049/jimmunol.167.8.4311

X. Zhang, S. Yu, K. Hoffmann, K. Yu, and R. Forster, Neonatal lymph node stromal cells drive myelodendritic lineage cells into a distinct population of CX3CR1+CD11b+F4/80+ regulatory macrophages in mice, Blood, vol.119, issue.17, pp.3975-3986, 2012.
DOI : 10.1182/blood-2011-06-359315