Fever in hospitalized HIV-infected patients in Western French Guiana: first think histoplasmosis

Vincent Vantilcke 1 Rachida Boukhari 2 Anne Jolivet 1 Cyrille Vautrin 1 Caroline Misslin 1 Antoine Adenis 3, 4 Mathieu Nacher 3, 4
1 Service de Médecine
2 Laboratoire de Biologie Médicale
3 CIC - Antilles Guyane - Centre d'investigation clinique Antilles-Guyane
4 CIC - Antilles Guyane - Centre d'Investigation Clinique Antilles-Guyane
Abstract : In Western French Guiana there was a dramatic increase in HIV-prevalence between 1990 and 2000. The present study describes the causes of fever among HIV patients hospitalized in the medical ward of the only hospital in the western part of French Guiana. A retrospective descriptive study was conducted between January 1st 2008 and June 30th 2010 in the department of medicine of Saint Laurent du Maroni Hospital. The main characteristics of 67 patients having presented with fever in the first 48 hours of hospitalization were described. Among patients with CD4<200/mm3 the main febrile opportunistic infection was disseminated histoplasmosis (41.1%). Among patients with CD4 counts <50/mm3 and fever without focal points 85.7% had disseminated histoplasmosis. Three patients died and all had disseminated histoplasmosis. Disseminated histoplasmosis is the most common febrile opportunistic infection in western French Guiana. Primary prophylaxis with itraconazole among immunocompromised patients seems warranted.
Keywords : Fever histoplasmosis primary prophylaxis French Guiana HIV
Type de document :
Article dans une revue
International Journal of STD and AIDS, SAGE Publications, 2014, 25, pp.656 - 661. 〈10.1177/0956462413516299〉
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https://www.hal.inserm.fr/inserm-01082409
Contributeur : Antoine Adenis <>
Soumis le : jeudi 13 novembre 2014 - 14:28:29
Dernière modification le : mercredi 18 juillet 2018 - 20:11:28
Document(s) archivé(s) le : samedi 14 février 2015 - 10:55:49

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Vincent Vantilcke, Rachida Boukhari, Anne Jolivet, Cyrille Vautrin, Caroline Misslin, et al.. Fever in hospitalized HIV-infected patients in Western French Guiana: first think histoplasmosis. International Journal of STD and AIDS, SAGE Publications, 2014, 25, pp.656 - 661. 〈10.1177/0956462413516299〉. 〈inserm-01082409〉

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