GLP-1-based strategies: a physiological analysis of differential mode of action.

Abstract : DPP4 inhibitors and GLP-1 receptor agonists used in incretin-based strategies treat Type 2 diabetes with different modes of action. The pharmacological blood GLP-1R agonist concentration targets pancreatic and some extrapancreatic GLP-1R, whereas DPP4i favors the physiological activation of the gut-brain-periphery axis that could allow clinicians to adapt the management of Type 2 diabetes, according to the patient's pathophysiological characteristics.
Type de document :
Article dans une revue
News in Physiological Sciences, American Physiological Society, 2014, 29 (2), pp.108-21. 〈10.1152/physiol.00009.2013〉
Liste complète des métadonnées

http://www.hal.inserm.fr/inserm-00995704
Contributeur : Marie Francoise Simon <>
Soumis le : vendredi 23 mai 2014 - 16:10:09
Dernière modification le : lundi 10 septembre 2018 - 15:38:57

Identifiants

Collections

Citation

Rémy Burcelin, Pierre Gourdy, Stéphane Dalle. GLP-1-based strategies: a physiological analysis of differential mode of action.. News in Physiological Sciences, American Physiological Society, 2014, 29 (2), pp.108-21. 〈10.1152/physiol.00009.2013〉. 〈inserm-00995704〉

Partager

Métriques

Consultations de la notice

100