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Fast Identification of Optimal Fascicle Configurations from Standard Clinical Diffusion MRI Using Akaike Information Criterion

Aymeric Stamm 1, 2, * Olivier Commowick 1 Patrick Pérez 3 Christian Barillot 1
* Corresponding author
1 VisAGeS - Vision, Action et Gestion d'informations en Santé
IRISA-D5 - SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE, INSERM - Institut National de la Santé et de la Recherche Médicale : U746, Inria Rennes – Bretagne Atlantique
3 Technicolor Imaging Science Lab
Technicolor [Cesson Sévigné]
Abstract : Analytic multi-compartment models have gained a tremen- dous popularity in the recent literature for studying the brain white matter microstructure from diffusion MRI. This class of models require the number of compartments to be known in advance. In the white matter however, several non-collinear bundles of axons, termed fascicles, often coexist in a same voxel. Determining the optimal fascicle configuration is a model selection problem. In this paper, we aim at proposing a novel approach to identify such a configuration from clinical diffusion MRI where only few diffusion images can be ac- quired and time is of the essence. Starting from a set of fitted models with increasing number of fascicles, we use Akaike information criterion to estimate the probability of each can- didate model to be the best Kullback-Leibler model. These probabilities are then used to average the different candidate models and output an MCM with optimal fascicle configura- tion. This strategy is fast and can be adapted to any multi- compartment model. We illustrate its implementation with the ball-and-stick model and show that we obtain better re- sults on single-shell low angular resolution diffusion MRI, compared to the state-of-the-art automatic relevance detection method, in a shorter processing time.
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Contributor : Olivier Commowick <>
Submitted on : Tuesday, May 6, 2014 - 6:09:45 PM
Last modification on : Friday, March 6, 2020 - 1:33:37 AM
Document(s) archivé(s) le : Wednesday, August 6, 2014 - 1:50:23 PM


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  • HAL Id : inserm-00987802, version 1


Aymeric Stamm, Olivier Commowick, Patrick Pérez, Christian Barillot. Fast Identification of Optimal Fascicle Configurations from Standard Clinical Diffusion MRI Using Akaike Information Criterion. IEEE International Symposium on Biomedical Imaging, Apr 2014, China. pp.238-241. ⟨inserm-00987802⟩



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