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Prospective study of Hepatitis E Virus infection among pregnant women in France.

Abstract : BACKGROUND: Hepatitis E Virus (HEV) infection has a poor prognosis among pregnant women from high endemic countries. HEV-prevalence and incidence among pregnant women is unknown in high-income countries such as France. This prospective study was conducted to assess HEV infection in this setting. FINDINGS: An overall HEV prevalence of 7.74% was observed among 315 pregnant women. Seroprevalence was higher in south than in north of France (29.3% vs. 3.6%, p < 0.0001), and women with detectable IgG were older. No IgG seroconversion or IgM detection were observed during pregnancy. CONCLUSIONS: Data suggest that HEV infection is a rare occurrence during pregnancy even in regions of western countries with high seroprevalence rates.
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Submitted on : Tuesday, May 6, 2014 - 5:06:23 PM
Last modification on : Wednesday, September 16, 2020 - 4:57:40 PM
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Christophe Renou, Vincent Gobert, Christophe Locher, Abdelouahab Moumen, Oumar Timbely, et al.. Prospective study of Hepatitis E Virus infection among pregnant women in France.. Virology Journal, BioMed Central, 2014, 11 (1), pp.68. ⟨10.1186/1743-422X-11-68⟩. ⟨inserm-00987740⟩

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