Identification of DNA ligase I related polypeptides in three different human cells. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Biochemical and Biophysical Research Communications Year : 1990

Identification of DNA ligase I related polypeptides in three different human cells.

Abstract

Partial purification of the DNA ligase from three human tissues (liver, thymus and lymphoblasts) revealed that each cell type contains several different polypeptides bearing a DNA ligase I activity. Their apparent molecular weights estimated after SDS PAGE, 130 kDa, 100 kDa and 80 kDa, are in agreement with previous reports. These polypeptides are related by proteolysis to a single higher molecular weight protein of 200 kDa which does not show DNA ligase activity but that could be a preprotein.
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Dates and versions

inserm-00966019 , version 1 (26-03-2014)

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  • HAL Id : inserm-00966019 , version 1
  • PUBMED : 2363731

Cite

Claude Prigent, Saïd Aoufouchi, Michel Philippe. Identification of DNA ligase I related polypeptides in three different human cells.. Biochemical and Biophysical Research Communications, 1990, 169 (3), pp.888-95. ⟨inserm-00966019⟩
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