Identification of DNA ligase I related polypeptides in three different human cells. - Archive ouverte HAL Access content directly
Journal Articles Biochemical and Biophysical Research Communications Year : 1990

Identification of DNA ligase I related polypeptides in three different human cells.

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Abstract

Partial purification of the DNA ligase from three human tissues (liver, thymus and lymphoblasts) revealed that each cell type contains several different polypeptides bearing a DNA ligase I activity. Their apparent molecular weights estimated after SDS PAGE, 130 kDa, 100 kDa and 80 kDa, are in agreement with previous reports. These polypeptides are related by proteolysis to a single higher molecular weight protein of 200 kDa which does not show DNA ligase activity but that could be a preprotein.
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Dates and versions

inserm-00966019 , version 1 (26-03-2014)

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  • HAL Id : inserm-00966019 , version 1
  • PUBMED : 2363731

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Claude Prigent, Saïd Aoufouchi, Michel Philippe. Identification of DNA ligase I related polypeptides in three different human cells.. Biochemical and Biophysical Research Communications, 1990, 169 (3), pp.888-95. ⟨inserm-00966019⟩
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