As that of many other scientific fields, the history of ultrasound clinical use for bone is made of booms and regressions. Clinical bone imaging technology is largely based on using X-rays. But since X-rays imaging does not provide all of the information that is needed by clinicians, particularly for bone strength assessment, in the second part of the twentieth century researchers turned to ultrasound. The first investigations using ultrasound for bone assessment reported in the late 1950s were designed to monitor fracture healing [1]. Despite the publication of interesting results, it took 25 years before diagnostic ultrasound succeeded in attracting clinicians in a completely different field, that of osteoporotic fracture risk prediction [2].