Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work., Brain Research Reviews, vol.33, issue.1, pp.95-130, 2000. ,
DOI : 10.1016/S0165-0173(00)00019-9
Alzheimer disease models and human neuropathology: similarities and differences, Acta Neuropathologica, vol.204, issue.1, pp.5-38, 2008. ,
DOI : 10.1007/s00401-007-0312-8
URL : https://hal.archives-ouvertes.fr/hal-00320572
Animal models of Alzheimer's disease and frontotemporal dementia, Nature Reviews Neuroscience, vol.12, issue.7, pp.532-544, 2008. ,
DOI : 10.1038/nrn2420
Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps, J Neurochem, vol.107, pp.1113-1123, 2008. ,
DOI : 10.1111/j.1471-4159.2008.05692.x
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2596975
Juvenile frontotemporal dementia with parkinsonism associated with Tau mutation G389R, J Alzheimer, vol.2013, issue.37, pp.769-776 ,
Neuropathological stageing of Alzheimer-related changes, Acta Neuropathologica, vol.80, issue.4, pp.239-259, 1991. ,
DOI : 10.1007/BF00308809
The biochemical pathway of neurofibrillary degeneration in aging and Alzheimer's disease, Neurology, vol.52, issue.6, pp.1158-1165, 1999. ,
DOI : 10.1212/WNL.52.6.1158
Modeling the Relation Between Neurofibrillary Tangles and Intellectual Status, Neurobiology of Aging, vol.18, issue.3, pp.267-273, 1997. ,
DOI : 10.1016/S0197-4580(97)80306-5
The significance of cortical pathology in progressive supranuclear palsy: Clinico-pathological data in 10 cases, Brain, vol.119, issue.4, pp.1123-1136, 1996. ,
DOI : 10.1093/brain/119.4.1123
Staging of Argyrophilic Grains: An Age-Associated Tauopathy, Journal of Neuropathology & Experimental Neurology, vol.63, issue.9, pp.911-918, 2004. ,
DOI : 10.1093/jnen/63.9.911
Brain homogenates from human tauopathies induce tau inclusions in mouse brain, Proceedings of the National Academy of Sciences, vol.110, issue.23, pp.9535-9540 ,
DOI : 10.1073/pnas.1301175110
Transmission and spreading of tauopathy in transgenic mouse brain, Nature Cell Biology, vol.8, issue.7, pp.909-913, 2009. ,
DOI : 10.1038/ncb1901
Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy, Journal of Neuroscience, vol.33, issue.3, pp.1024-1037, 2013. ,
DOI : 10.1523/JNEUROSCI.2642-12.2013
Identification of oligomers at early stages of tau aggregation in Alzheimer's disease, The FASEB Journal, vol.26, issue.5, pp.1946-1959, 2012. ,
DOI : 10.1096/fj.11-199851
Propagation of Tau Misfolding from the Outside to the Inside of a Cell, Journal of Biological Chemistry, vol.284, issue.19, pp.12845-12852, 2009. ,
DOI : 10.1074/jbc.M808759200
Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles, Journal of Biological Chemistry, vol.286, issue.17, pp.15317-15331, 2011. ,
DOI : 10.1074/jbc.M110.209296
Paired Helical Filaments from Alzheimer Disease Brain Induce Intracellular Accumulation of Tau Protein in Aggresomes, Journal of Biological Chemistry, vol.287, issue.24, pp.20522-20533, 2012. ,
DOI : 10.1074/jbc.M111.323279
Trans-cellular Propagation of Tau Aggregation by Fibrillar Species, Journal of Biological Chemistry, vol.287, issue.23, pp.19440-19451, 2012. ,
DOI : 10.1074/jbc.M112.346072
Neurofibrillary tangle-like tau pathology induced by synthetic tau fibrils in primary neurons over-expressing mutant tau, FEBS Letters, vol.50, issue.6, pp.717-723, 2013. ,
DOI : 10.1016/j.febslet.2013.01.051
Propagation of Tau Pathology in a Model of Early Alzheimer's Disease, Neuron, vol.73, issue.4, pp.685-697, 2012. ,
DOI : 10.1016/j.neuron.2011.11.033
Trans-Synaptic Spread of Tau Pathology In Vivo, PLoS ONE, vol.25, issue.2, p.31302, 2012. ,
DOI : 10.1371/journal.pone.0031302.g008
Lentiviral Delivery of the Human Wild-type Tau Protein Mediates a Slow and Progressive Neurodegenerative Tau Pathology in the Rat Brain, Molecular Therapy, vol.21, issue.7, pp.1358-1368, 2013. ,
DOI : 10.1038/mt.2013.66
Dysregulation of human brain microtubule-associated tau mRNA maturation in myotonic dystrophy type 1, Human Molecular Genetics, vol.10, issue.19, pp.2143-2155, 2001. ,
DOI : 10.1093/hmg/10.19.2143
Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus, J Neurosci, vol.20, pp.5587-5593, 2000. ,
Immunohistochemical detection of transgene expression in the brain using small epitope tags, BMC Biotechnology, vol.10, issue.1, p.16, 2010. ,
DOI : 10.1186/1472-6750-10-16
The Peptidylprolyl cis/trans-Isomerase Pin1 Modulates Stress-induced Dephosphorylation of Tau in Neurons: IMPLICATION IN A PATHOLOGICAL MECHANISM RELATED TO ALZHEIMER DISEASE, Journal of Biological Chemistry, vol.281, issue.28, pp.19296-19304, 2006. ,
DOI : 10.1074/jbc.M601849200
A Microfluidic Chamber for Analysis of Neuron-to-Cell Spread and Axonal Transport of an Alpha-Herpesvirus, PLoS ONE, vol.102, issue.6, p.2382, 2008. ,
DOI : 10.1371/journal.pone.0002382.s002
A microfluidic culture platform for CNS axonal injury, regeneration and transport, Nature Methods, vol.20, issue.8, pp.599-605, 2005. ,
DOI : 10.1038/nmeth777
Neuron-to-neuron transmission of ??-synuclein fibrils through axonal transport, Annals of Neurology, vol.69, issue.4, pp.517-524, 2012. ,
DOI : 10.1002/ana.23747
URL : https://hal.archives-ouvertes.fr/hal-01183063
Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons, Journal of Biological Chemistry, vol.288, issue.3, pp.1856-1870, 2013. ,
DOI : 10.1074/jbc.M112.394528
URL : https://hal.archives-ouvertes.fr/pasteur-00874385
Quantitative four-dimensional tracking of cytoplasmic and nuclear HIV-1 complexes, Nature Methods, vol.272, issue.10, pp.817-824, 2006. ,
DOI : 10.1038/nmeth928
URL : https://hal.archives-ouvertes.fr/pasteur-00163778
HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore, The EMBO Journal, vol.9, issue.12, pp.3025-3037, 2007. ,
DOI : 10.1038/sj.emboj.7601740
URL : https://hal.archives-ouvertes.fr/hal-00167661
Spatial organization of direct hippocampal field CA1 axonal projections to the rest of the cerebral cortex, Brain Research Reviews, vol.56, issue.1, pp.1-26, 2007. ,
DOI : 10.1016/j.brainresrev.2007.05.002
Pathway tracing using biotinylated dextran amines, Journal of Neuroscience Methods, vol.103, issue.1, pp.23-37, 2000. ,
DOI : 10.1016/S0165-0270(00)00293-4
Monoclonal antibodies with selective specificity for Alzheimer Tau are directed against phosphatase-sensitive epitopes, Acta Neuropathologica, vol.84, issue.3, pp.265-272, 1992. ,
DOI : 10.1007/BF00227819
Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation, Journal of Biological Chemistry, vol.283, issue.46, pp.32066-32076, 2008. ,
DOI : 10.1074/jbc.M805300200
Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau, Journal of Neuroscience Research, vol.85, issue.2, pp.128-132, 1997. ,
DOI : 10.1002/(SICI)1097-4547(19970415)48:2<128::AID-JNR5>3.0.CO;2-E
Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein, pp.9340-9351, 2002. ,
Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission, European Journal of Neuroscience, vol.277, issue.Suppl 2 ,
DOI : 10.1111/ejn.12229
Extracellular tau promotes intracellular calcium increase through M1 and M3 muscarinic receptors in neuronal cells, Molecular and Cellular Neuroscience, vol.37, issue.4, pp.673-681, 2008. ,
DOI : 10.1016/j.mcn.2007.12.010
Extracellular Tau Levels Are Influenced by Variability in Tau That Is Associated with Tauopathies, Journal of Biological Chemistry, vol.287, issue.51, pp.42751-42762, 2012. ,
DOI : 10.1074/jbc.M112.380642
Constitutive secretion of tau protein by an unconventional mechanism, Neurobiology of Disease, vol.48, issue.3, pp.356-366, 2012. ,
DOI : 10.1016/j.nbd.2012.05.021
Hyperphosphorylation and Cleavage at D421 Enhance Tau Secretion, PLoS ONE, vol.168, issue.5, p.36873, 2012. ,
DOI : 10.1371/journal.pone.0036873.t001
URL : http://doi.org/10.1371/journal.pone.0036873
Physiological release of endogenous tau is stimulated by neuronal activity, EMBO reports, vol.309, issue.4, pp.389-394, 2013. ,
DOI : 10.1016/j.nbd.2011.01.029
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds, Proceedings of the National Academy of Sciences, vol.110, issue.33, pp.3138-3147 ,
DOI : 10.1073/pnas.1301440110
Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles, FEBS Letters, vol.32, issue.1, pp.47-54, 2012. ,
DOI : 10.1016/j.febslet.2011.11.022
CaMKII Activation in the Entorhinal Cortex Disrupts Previously Encoded Spatial Memory, Neuron, vol.50, issue.2, pp.309-318, 2006. ,
DOI : 10.1016/j.neuron.2006.03.035
???Prion-Like??? Templated Misfolding in Tauopathies, Brain Pathology, vol.8, issue.3, pp.342-349, 2013. ,
DOI : 10.1111/bpa.12044
Tissue-nonspecific Alkaline Phosphatase Promotes the Neurotoxicity Effect of Extracellular Tau, Journal of Biological Chemistry, vol.285, issue.42, pp.32539-32548, 2010. ,
DOI : 10.1074/jbc.M110.145003
Formation and Propagation of Tau Oligomeric Seeds, Frontiers in Neurology, vol.4, p.93, 2013. ,
DOI : 10.3389/fneur.2013.00093
Targeting Phospho-Ser422 by Active Tau Immunotherapy in the THYTau22 Mouse Model: A Suitable Therapeutic Approach, Current Alzheimer Research, vol.9, issue.4, pp.397-405 ,
DOI : 10.2174/156720512800492503
URL : https://hal.archives-ouvertes.fr/inserm-00664452
Anti-Tau Antibodies that Block Tau Aggregate Seeding In??Vitro Markedly Decrease Pathology and Improve Cognition In??Vivo, Neuron, vol.80, issue.2, pp.402-414, 2013. ,
DOI : 10.1016/j.neuron.2013.07.046