Iron metabolism and the innate immune response to infection, Microbes and Infection, vol.14, issue.3, pp.207-216, 2012. ,
DOI : 10.1016/j.micinf.2011.10.001
Viral infection and iron metabolism, Nature Reviews Microbiology, vol.78, issue.7, pp.541-552, 2008. ,
DOI : 10.1038/nrmicro1930
Hepcidin and the Iron-Infection Axis, Science, vol.338, issue.6108, pp.768-772 ,
DOI : 10.1126/science.1224577
Flow cytometry measurement of the labile iron pool in human hematopoietic cells, Cytometry Part A, vol.270, issue.1, pp.22-27, 2008. ,
DOI : 10.1002/cyto.a.20491
Hepcidin induces HIV-1 transcription inhibited by ferroportin, Retrovirology, vol.7, issue.1, p.104, 2010. ,
DOI : 10.1186/1742-4690-7-104
Elevated Iron Status Strongly Predicts Mortality in West African Adults With HIV Infection, JAIDS Journal of Acquired Immune Deficiency Syndromes, vol.46, issue.4, pp.498-507, 2007. ,
DOI : 10.1097/QAI.0b013e31815b2d4b
Mortality in HIV infection is independently predicted by host iron status and SLC11A1 and HP genotypes, with new evidence of a gene-nutrient interaction, American Journal of Clinical Nutrition, vol.90, issue.1, pp.225-233, 2009. ,
DOI : 10.3945/ajcn.2009.27709
Role of cellular iron and oxygen in the regulation of HIV-1 infection, Future Virology, vol.8, issue.3, pp.301-311, 2013. ,
DOI : 10.2217/fvl.13.6
HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis, Proceedings of the National Academy of Sciences, vol.102, issue.31, pp.11017-11022, 2005. ,
DOI : 10.1073/pnas.0504823102
Role of Nef in primate lentiviral immunopathogenesis, Cellular and Molecular Life Sciences, vol.65, issue.17, pp.2621-2636, 2008. ,
DOI : 10.1007/s00018-008-8094-2
Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz, Nature, vol.19, issue.7254, pp.515-519, 2009. ,
DOI : 10.1038/nature08200
Comparing HIV-1 and HIV-2 infection: Lessons for viral immunopathogenesis, Reviews in Medical Virology, vol.18, issue.Suppl 2, pp.221-240 ,
DOI : 10.1002/rmv.1739
Natural SIV Hosts: Showing AIDS the Door, Science, vol.335, issue.6073, pp.1188-1193, 2012. ,
DOI : 10.1126/science.1217550
Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1, Cell, vol.125, issue.6, pp.1055-1067, 2006. ,
DOI : 10.1016/j.cell.2006.04.033
Macrophages and their relevance in Human Immunodeficiency Virus Type I infection, Retrovirology, vol.9, issue.1, p.82 ,
DOI : 10.1371/journal.pone.0037477
A single viral protein HCMV US2 affects antigen presentation and intracellular iron homeostasis by degradation of classical HLA class I and HFE molecules, Blood, vol.101, issue.7, pp.2858-2864, 2003. ,
DOI : 10.1182/blood-2002-07-2158
Genetic diversity of human immunodeficiency virus type 2: evidence for distinct sequence subtypes with differences in virus biology, pp.7433-7447, 1994. ,
Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain, pp.8373-8382, 2008. ,
Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis, The EMBO Journal, vol.18, issue.10, pp.2722-2733, 1999. ,
DOI : 10.1093/emboj/18.10.2722
Sorting it out: Figure 1., The Journal of Cell Biology, vol.115, issue.2, pp.203-208, 2003. ,
DOI : 10.1074/jbc.M304384200
Comprehensive Analysis of Nef Functions Selected in Simian Immunodeficiency Virus-Infected Macaques, Journal of Virology, vol.78, issue.19, pp.10588-10597, 2004. ,
DOI : 10.1128/JVI.78.19.10588-10597.2004
Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection. JV i r o l2006, pp.8047-8059 ,
A Structural Explanation for the Recognition of Tyrosine-Based Endocytotic Signals, Science, vol.282, issue.5392, pp.1327-1332, 1998. ,
DOI : 10.1126/science.282.5392.1327
A Flow Cytometry-Based FRET Assay to Identify and Analyse Protein-Protein Interactions in Living Cells, PLoS ONE, vol.3, issue.2, p.9344, 2010. ,
DOI : 10.1371/journal.pone.0009344.s005
Downregulation of CD4 by Human Immunodeficiency Virus Type 1 Nef Is Dependent on Clathrin and Involves Direct Interaction of Nef with the AP2 Clathrin Adaptor, Journal of Virology, vol.81, issue.8, pp.3877-3890, 2007. ,
DOI : 10.1128/JVI.02725-06
Conversion of Red Fluorescent Protein into a Bright Blue Probe, Chemistry & Biology, vol.15, issue.10, pp.1116-1124, 2008. ,
DOI : 10.1016/j.chembiol.2008.08.006
Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue, Retrovirology, vol.7, issue.1, 2010. ,
DOI : 10.1186/1742-4690-7-1
Nef-induced Alteration of the Early/Recycling Endosomal Compartment Correlates with Enhancement of HIV-1 Infectivity, Journal of Biological Chemistry, vol.280, issue.6, pp.5032-5044, 2005. ,
DOI : 10.1074/jbc.M401202200
Human Immunodeficiency Virus Type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains, Retrovirology, vol.4, issue.1, p.70, 2007. ,
DOI : 10.1186/1742-4690-4-70
Single Nef Proteins from HIV Type 1 Subtypes C and F Fail to Upregulate Invariant Chain Cell Surface Expression But Are Active for Other Functions, AIDS Research and Human Retroviruses, vol.25, issue.3, pp.285-296, 2009. ,
DOI : 10.1089/aid.2008.0132
Iron status and the outcome of HIV infection: an overview. JC l i nV i r o l2001, pp.111-115 ,
Dose of desferrioxamine and evolution of HIV-1 infection in thalassaemic patients, British Journal of Haematology, vol.184, issue.4, pp.849-852, 1994. ,
DOI : 10.1038/ki.1989.301
Serum Ferritin, Desferrioxamine, and Evolution of HIV-1 Infection in Thalassemic Patients, Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, vol.18, issue.5, pp.473-478, 1998. ,
DOI : 10.1097/00042560-199808150-00009
Lower Survival in AIDS Patients Receiving Dapsone Compared with Aerosolized Pentamidine for Secondary Prophylaxis of Pneumocystis carinii Pneumonia, Journal of Infectious Diseases, vol.172, issue.3, pp.656-664, 1995. ,
DOI : 10.1093/infdis/172.3.656
Haptoglobin polymorphism, iron metabolism and mortality in HIV infection, AIDS, vol.12, issue.9, pp.1027-1032, 1998. ,
DOI : 10.1097/00002030-199809000-00010
Bone marrow macrophage iron grade and survival of HIV-seropositive patients, AIDS, vol.13, issue.3, pp.375-380, 1999. ,
DOI : 10.1097/00002030-199902250-00010
Epidemiology of anemia in human immunodeficiency virus (HIV)-infected persons: results from the multistate adult and adolescent spectrum of HIV disease surveillance project, Blood, vol.91, pp.301-308, 1998. ,
Anemia is an independent predictor of mortality and immunologic progression of disease among women with HIV in Tanzania, J Acquir Immune Defic Syndr, vol.40, pp.219-225, 2005. ,
Iron, Haptoglobin Phenotype, and HIV-1 Viral Load: A Cross-Sectional Study Among Pregnant Zimbabwean Women, JAIDS Journal of Acquired Immune Deficiency Syndromes, vol.33, issue.1 ,
DOI : 10.1097/00126334-200305010-00011
The association of serum ferritin and transferrin receptor concentrations with mortality in women with human immunodeficiency virus infection, Haematologica, vol.91, pp.739-743, 2006. ,
B and HIV Type 1 Activation due to Oxidative Stress, AIDS Research and Human Retroviruses, vol.11, issue.9, pp.1049-1061, 1995. ,
DOI : 10.1089/aid.1995.11.1049
Iron chelators ICL670 and 311 inhibit HIV-1 transcription, Virology, vol.367, issue.2, pp.324-333, 2007. ,
DOI : 10.1016/j.virol.2007.06.011
Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A, Retrovirology, vol.6, issue.1, p.90, 2009. ,
DOI : 10.1186/1742-4690-6-90
Identification of a host protein essential for assembly of immature HIV-1 capsids, Nature, vol.415, issue.6867, pp.88-92, 2002. ,
DOI : 10.1038/415088a
Iron Chelators of the Di-2-pyridylketone Thiosemicarbazone and 2-Benzoylpyridine Thiosemicarbazone Series Inhibit HIV-1 Transcription: Identification of Novel Cellular Targets--Iron, Cyclin-Dependent Kinase (CDK) 2, and CDK9, Molecular Pharmacology, vol.79, issue.1, pp.185-196, 2011. ,
DOI : 10.1124/mol.110.069062
Host iron redistribution as a risk factor for incident tuberculosis in HIV infection: an 11-year retrospective cohort study, BMC Infectious Diseases, vol.4, issue.1, p.48, 2013. ,
DOI : 10.1007/s00335-010-9280-8
Micronutrients, N-Acetyl Cysteine, Probiotics and Prebiotics, a Review of Effectiveness in Reducing HIV Progression, Nutrients, vol.2, issue.6, pp.626-651, 2010. ,
DOI : 10.3390/nu2060626
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx, Nature, vol.38, issue.7353, pp.654-657, 2011. ,
DOI : 10.1038/nature10117
URL : https://hal.archives-ouvertes.fr/hal-00616451
The level of monocyte turnover predicts disease progression in the macaque model of AIDS, Blood, vol.114, issue.14, pp.2917-2925, 2009. ,
DOI : 10.1182/blood-2009-02-204263
Macrophage Internal HIV-1 Is Protected from Neutralizing Antibodies, Journal of Virology, vol.86, issue.5 ,
DOI : 10.1128/JVI.05915-11
Down-Modulation of Mature Major Histocompatibility Complex Class II and Up-Regulation of Invariant Chain Cell Surface Expression Are Well-Conserved Functions of Human and Simian Immunodeficiency Virus nef Alleles, Journal of Virology, vol.77, issue.19, pp.10548-10556, 2003. ,
DOI : 10.1128/JVI.77.19.10548-10556.2003
Lentiviral Nef suppresses iron uptake in a strain specific manner through inhibition of Transferrin endocytosis, Retrovirology, vol.11, issue.1, 2014. ,
DOI : 10.1128/JVI.77.19.10548-10556.2003
URL : https://hal.archives-ouvertes.fr/inserm-00925639