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LC-MS/MS screen for xenobiotics and metabolites.

Abstract : Liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is now considered as a perfect complement to HPLC-DAD (diode array detection) and gas chromatography (GC)-MS for the general unknown screening of drugs and toxic compounds.Here we describe a procedure applied routinely in our laboratory for clinical and forensic applications using the QTRAP™ technology.
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Submitted on : Tuesday, January 7, 2014 - 5:05:47 PM
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François-Ludovic Sauvage, Pierre Marquet. LC-MS/MS screen for xenobiotics and metabolites.. Methods in Molecular Biology, Humana Press/Springer Imprint, 2012, 902, pp.129-38. ⟨10.1007/978-1-61779-934-1_11⟩. ⟨inserm-00925227⟩



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