. Stavudine, 40 mg/12 h (! 60 kg) 20 mg  2/24 h 20 mg/24 h 20 mg/24 h 20 mg/24 h 30 mg/12 h (< 60 kg) 15

. Zidovudine, Retrovir W ) 300 mg/12 h 300 mg/12 h 150 mg/12 h 150 mg/12 h 150 mg

. Ténofovir, 300 mg/24 h 300 mg/48 h 300 mg/72 h 300 mg 1 fois par semaine Maraviroc (Celsentri W ) Non évalué + IP/ritonavir 150 mg/24 h 1 150 mg/24 h 150 mg

C. Wyatt, J. Winston, C. Malvestutto, D. Fishbein, I. Barash et al., Chronic kidney disease in HIV infection: an urban epidemic, AIDS, vol.21, issue.15, pp.2101-2104, 2007.
DOI : 10.1097/QAD.0b013e3282ef1bb4

G. Lucas, S. Mehta, M. Atta, G. Kirk, N. Galai et al., End-stage renal disease and chronic kidney disease in a cohort of African-American HIV-infected and at-risk HIV-seronegative participants followed between 1988 and 2004, AIDS, vol.21, issue.18, pp.2435-2478, 1988.
DOI : 10.1097/QAD.0b013e32827038ad

A. Mocroft, O. Kirk, P. Reiss, D. Wit, S. Sedlacek et al., Estimated glomerular filtration rate, chronic kidney disease and antiretroviral drug use in HIV-positive patients, AIDS, vol.24, issue.11, pp.1667-78, 2010.
DOI : 10.1097/QAD.0b013e328339fe53

E. Déti, R. Thiébaut, F. Bonnet, S. Lawson-ayayi, M. Dupon et al., Prevalence and factors associated with renal impairment in HIV-infected patients, ANRS C03 Aquitaine Cohort, France, HIV Medicine, vol.11, issue.5, pp.308-325, 2010.
DOI : 10.1111/j.1468-1293.2009.00780.x

J. Trullas, A. Mocroft, F. Cofan, J. Tourret, A. Moreno et al., Dialysis and Renal Transplantation in HIV-Infected Patients: a European Survey, JAIDS Journal of Acquired Immune Deficiency Syndromes, vol.55, issue.5, pp.582-591, 2010.
DOI : 10.1097/QAI.0b013e3181efbe59

G. Genovese, D. Friedman, and M. Ross, Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans, Science, vol.329, issue.5993, pp.841-846, 2010.
DOI : 10.1126/science.1193032

R. Medapalli, J. He, and P. Klotman, HIV-associated nephropathy: pathogenesis, Current Opinion in Nephrology and Hypertension, vol.20, issue.3, pp.306-317, 2011.
DOI : 10.1097/MNH.0b013e328345359a

J. Kopp, G. Nelson, K. Sampath, R. Johnson, G. Genovese et al., APOL1 Genetic Variants in Focal Segmental Glomerulosclerosis and HIV-Associated Nephropathy, Journal of the American Society of Nephrology, vol.22, issue.11, pp.2129-2166, 2011.
DOI : 10.1681/ASN.2011040388

S. Gupta, J. Eustace, J. Winston, I. Boydstun, T. Ahuja et al., Guidelines for the Management of Chronic Kidney Disease in HIV-Infected Patients: Recommendations of the HIV Medicine Association of the Infectious Diseases Society of America, Clinical Infectious Diseases, vol.40, issue.11, pp.1559-85, 2005.
DOI : 10.1086/430257

S. Madhavan, O. Toole, J. Konieczkowski, M. Ganesan, S. Bruggeman et al., APOL1 Localization in Normal Kidney and Nondiabetic Kidney Disease, Journal of the American Society of Nephrology, vol.22, issue.11, pp.2119-2147, 2011.
DOI : 10.1681/ASN.2011010069

G. Lucas, J. Eustace, S. Sozio, E. Mentari, K. Appiah et al., Highly active antiretroviral therapy and the incidence of HIV-1-associated nephropathy, AIDS, vol.18, issue.3, pp.541-547, 2004.
DOI : 10.1097/00002030-200402200-00022

R. Wali, C. Drachenberg, J. Papadimitriou, S. Keay, and E. Ramos, HIV-1-associated nephropathy and response to highly-active antiretroviral therapy, The Lancet, vol.352, issue.9130, pp.783-787, 1998.
DOI : 10.1016/S0140-6736(98)24037-2

X. Lescure, C. Flateau, J. Pacanowski, I. Brocheriou, E. Rondeau et al., HIVassociated kidney glomerular diseases: changes with time and HAART, Nephrol Dial Transpl, 2011.
DOI : 10.1093/ndt/gfr676

URL : https://hal.archives-ouvertes.fr/inserm-00919151

S. Parkhie, D. Fine, G. Lucas, and M. Atta, Characteristics of Patients with HIV and Biopsy-Proven Acute Interstitial Nephritis, Clinical Journal of the American Society of Nephrology, vol.5, issue.5, pp.798-804, 2010.
DOI : 10.2215/CJN.08211109

E. Daugas, E. Plaisier, J. Boffa, J. Guiard-schmid, J. Pacanowski et al., Acute renal failure associated with immune restoration inflammatory syndrome, Nature Clinical Practice Nephrology, vol.67, issue.10, pp.594-602, 2006.
DOI : 10.1038/ncpneph0282

L. Zafrani, P. Coppo, S. Dettwiler, V. Molinier-frenkel, F. Agbalika et al., Nephropathy associated with the diffuse infiltrative lymphocytosis syndrome, Kidney International, vol.72, issue.2, pp.219-243, 2007.
DOI : 10.1038/sj.ki.5002207

H. Izzedine, M. Harris, and M. Perazella, The nephrotoxic effects of HAART, Nature Reviews Nephrology, vol.14, issue.10, pp.563-73, 2009.
DOI : 10.1038/nrneph.2009.142

E. Daugas, J. Rougier, and G. Hill, HAART-related nephropathies in HIV-infected patients, Kidney International, vol.67, issue.2, pp.393-403, 2005.
DOI : 10.1111/j.1523-1755.2005.67096.x

D. Verhelst, M. Monge, J. Meynard, B. Fouqueray, B. Mougenot et al., Fanconi syndrome and renal failure induced by tenofovir: A first case report, American Journal of Kidney Diseases, vol.40, issue.6, pp.1331-1334, 2002.
DOI : 10.1053/ajkd.2002.36924

A. Malik, P. Abraham, and N. Malik, Acute renal failure and Fanconi syndrome in an AIDS patient on tenofovir treatment???case report and review of literature, Journal of Infection, vol.51, issue.2, pp.61-66, 2005.
DOI : 10.1016/j.jinf.2004.08.031

S. Rodríguez-nóvoa, P. Labarga, V. Soriano, D. Egan, M. Albalater et al., Predictors of Kidney Tubular Dysfunction in HIV???Infected Patients Treated with Tenofovir: A Pharmacogenetic Study, Clinical Infectious Diseases, vol.48, issue.11, pp.108-124, 2009.
DOI : 10.1086/598507

P. Labarga, P. Barreiro, L. Martin-carbonero, S. Rodriguez-novoa, C. Solera et al., Kidney tubular abnormalities in the absence of impaired glomerular function in HIV patients treated with tenofovir, AIDS, vol.23, issue.6, pp.689-96, 2009.
DOI : 10.1097/QAD.0b013e3283262a64

M. Horberg, B. Tang, W. Towner, M. Silverberg, S. Bersoff-matcha et al., Impact of Tenofovir on Renal Function in HIV-Infected, Antiretroviral-Naive Patients, JAIDS Journal of Acquired Immune Deficiency Syndromes, vol.53, issue.1, pp.62-71, 2010.
DOI : 10.1097/QAI.0b013e3181be6be2

L. Herlitz, S. Mohan, M. Stokes, J. Radhakrishnan, D. Agati et al., Tenofovir nephrotoxicity: acute tubular necrosis with distinctive clinical, pathological, and mitochondrial abnormalities, Kidney International, vol.78, issue.11, pp.1171-1178, 2010.
DOI : 10.1038/ki.2010.318

URL : http://doi.org/10.1038/ki.2010.318

S. Rodriguez-nóvoa, E. Alvarez, P. Labarga, and V. Soriano, Renal toxicity associated with tenofovir use, Expert Opinion on Drug Safety, vol.26, issue.5, pp.545-59, 2010.
DOI : 10.1111/j.1468-1293.2009.00716.x

J. Pacanowski, J. Poirier, I. Petit, J. Meynard, and P. Girard, Atazanavir urinary stones in an HIV-infected patient, AIDS, vol.20, issue.16, p.2131, 2006.
DOI : 10.1097/01.aids.0000247571.88256.90

C. Couzigou, M. Daudon, J. Meynard, F. Borsa-lebas, D. Higueret et al., Urolithiasis in HIV-Positive Patients Treated with Atazanavir, Clinical Infectious Diseases, vol.45, issue.8, pp.105-113, 2007.
DOI : 10.1086/521930

H. Izzedine, M. 'rad, M. Bardier, A. Daudon, M. Salmon et al., Atazanavir crystal nephropathy, AIDS, vol.21, issue.17, pp.2357-2365, 2007.
DOI : 10.1097/QAD.0b013e3282f17503

D. Viglietti, J. Verine, D. Castro, N. Scemla, A. Daudon et al., Chronic interstitial nephritis in an HIV type-1-infected patient receiving ritonavir-boosted atazanavir, Antiviral Therapy, vol.16, issue.1, pp.119-140, 2011.
DOI : 10.3851/IMP1700