Cell labeling with magnetic nanoparticles: Opportunity for magnetic cell imaging and cell manipulation

Jelena Kolosnjaj-Tabi; Claire Wilhelm; Olivier Clément; Florence Gazeau

Cell labeling with magnetic nanoparticles: Opportunity for magnetic cell imaging and cell manipulation

Jelena Kolosnjaj-Tabi ^{1, 2} Claire Wilhelm ^{1, *} Olivier Clément ² Florence Gazeau ^{1, *}

* Auteur correspondant

2 PARCC - U970 - Paris-Centre de Recherche Cardiovasculaire

Abstract : This tutorial describes a method of controlled cell labeling with citrate-coated ultra small superparamagnetic iron oxide nanoparticles. This method may provide basically all kinds of cells with sufficient magnetization to allow cell detection by high-resolution magnetic resonance imaging (MRI) and to enable potential magnetic manipulation. In order to efficiently exploit labeled cells, quantify the magnetic load and deliver or follow-up magnetic cells, we herein describe the main requirements that should be applied during the labeling procedure. Moreover we present some recommendations for cell detection and quantification by MRI and detail magnetic guiding on some real-case studies in vitro and in vivo.

Type de document :

Article dans une revue

Journal of Nanobiotechnology, BioMed Central, 2013, 11 (Suppl 1), pp.S7

Domaine :

Sciences du Vivant [q-bio] / Biotechnologies

Informatique [cs] / Biotechnologie

Liste complète des métadonnées

Littérature citée [46 références] Voir Masquer Télécharger

http://www.hal.inserm.fr/inserm-00916510
Contributeur : Ed. Bmc <>
Soumis le : mardi 10 décembre 2013 - 13:13:56
Dernière modification le : jeudi 11 janvier 2018 - 06:14:29
Document(s) archivé(s) le : vendredi 14 mars 2014 - 09:57:17

Cell labeling with magnetic nanoparticles: Opportunity for magnetic cell imaging and cell manipulation

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Cell labeling with magnetic nanoparticles: Opportunity for magnetic cell imaging and cell manipulation

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