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Journal Articles Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference Year : 2013

Multiobjective patient-specific estimation of a coronary circulation model for triple vessel disease.

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Abstract

Computational models can help understand the hemodynamics of the coronary circulation, which is of the upmost importance to help clinicians before, during and after a coronary artery bypass graft surgery. In this paper, we propose a multiobjective optimization method for parameter estimation of a computational model representing the coronary circulation on patients with a triple vessel disease. This estimation was not based on any assumption regarding the development of the collateral circulation, like in previous works. Indeed, the collateral development of a given patient is estimated through the model parameters. Parameter estimation was performed using clinical data from three patients, obtained before and during an off-pump coronary artery bypass graft surgery (CABG). Results showed a better performance when comparing the simulation with clinical data, since the total error estimation for three patients was reduced by 40 ± 22%. Moreover, the proposed method provides new insight regarding the heterogeneous configuration of the alternative collateral vessels.
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Dates and versions

inserm-00881719 , version 1 (08-11-2013)

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David Ojeda, Virginie Le Rolle, Agnès Drochon, Majid Harmouche, Herve Corbineau, et al.. Multiobjective patient-specific estimation of a coronary circulation model for triple vessel disease.. Conference proceedings : .. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2013, 2013, pp.3877-80. ⟨10.1109/EMBC.2013.6610391⟩. ⟨inserm-00881719⟩
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