Skip to Main content Skip to Navigation
Journal articles

A model-based approach for the evaluation of vagal and sympathetic activities in a newborn lamb.

Abstract : This paper proposes a baroreflex model and a recursive identification method to estimate the time-varying vagal and sympathetic contributions to heart rate variability during autonomic maneuvers. The baroreflex model includes baroreceptors, cardiovascular control center, parasympathetic and sympathetic pathways. The gains of the global afferent sympathetic and vagal pathways are identified recursively. The method has been validated on data from newborn lambs, which have been acquired during the application of an autonomic maneuver, without medication and under beta-blockers. Results show a close match between experimental and simulated signals under both conditions. The vagal and sympathetic contributions have been simulated and, as expected, it is possible to observe different baroreflex responses under beta-blockers compared to baseline conditions.
Complete list of metadatas

Cited literature [16 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00881084
Contributor : Lotfi Senhadji <>
Submitted on : Thursday, November 7, 2013 - 2:31:33 PM
Last modification on : Thursday, March 5, 2020 - 6:38:47 PM
Long-term archiving on: : Friday, April 7, 2017 - 10:42:27 PM

Identifiers

Collections

Citation

Virginie Le Rolle, David Ojeda, Alain Beuchee, Jean-Paul Praud, Patrick Pladys, et al.. A model-based approach for the evaluation of vagal and sympathetic activities in a newborn lamb.. Conference proceedings : .. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, Institute of Electrical and Electronics Engineers (IEEE), 2013, 2013, pp.3881-4. ⟨10.1109/EMBC.2013.6610392⟩. ⟨inserm-00881084⟩

Share

Metrics

Record views

548

Files downloads

736