A model-based approach for the evaluation of vagal and sympathetic activities in a newborn lamb. - Archive ouverte HAL Access content directly
Journal Articles Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference Year : 2013

A model-based approach for the evaluation of vagal and sympathetic activities in a newborn lamb.

(1) , (1) , (1, 2) , (3) , (1) , (1)
1
2
3

Abstract

This paper proposes a baroreflex model and a recursive identification method to estimate the time-varying vagal and sympathetic contributions to heart rate variability during autonomic maneuvers. The baroreflex model includes baroreceptors, cardiovascular control center, parasympathetic and sympathetic pathways. The gains of the global afferent sympathetic and vagal pathways are identified recursively. The method has been validated on data from newborn lambs, which have been acquired during the application of an autonomic maneuver, without medication and under beta-blockers. Results show a close match between experimental and simulated signals under both conditions. The vagal and sympathetic contributions have been simulated and, as expected, it is possible to observe different baroreflex responses under beta-blockers compared to baseline conditions.
Fichier principal
Vignette du fichier
inserm-00881084_edited.pdf (270.27 Ko) Télécharger le fichier
Vignette du fichier
A_model-based_approach_for_the_evaluation_of_vagal_and_sympathetic_activities_in_a_newborn_lamb.pdf (834.34 Ko) Télécharger le fichier
Origin : Files produced by the author(s)
Origin : Files produced by the author(s)
Loading...

Dates and versions

inserm-00881084 , version 1 (07-11-2013)

Identifiers

Cite

Virginie Le Rolle, David Ojeda, Alain Beuchee, Jean-Paul Praud, Patrick Pladys, et al.. A model-based approach for the evaluation of vagal and sympathetic activities in a newborn lamb.. Conference proceedings : .. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2013, 2013, pp.3881-4. ⟨10.1109/EMBC.2013.6610392⟩. ⟨inserm-00881084⟩
209 View
280 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More