A. Agmon and B. W. Connors, Thalamocortical responses of mouse somatosensory (barrel) cortexin vitro, Neuroscience, vol.41, issue.2-3, pp.365-379, 1991.
DOI : 10.1016/0306-4522(91)90333-J

E. Aronica, J. A. Gorter, G. H. Jansen, S. Leenstra, B. Yankaya et al., Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex, Acta Neuropathol, vol.101, pp.449-459, 2001.

M. Avoli, P. Gloor, G. Kostopoulos, and J. Gotman, An analysis of penicillin-induced generalized spike and wave discharges using simultaneous recordings of cortical and thalamic single neurons, J.Neurophysiol, vol.50, pp.819-837, 1983.

M. Avoli, J. Louvel, I. Kurcewicz, R. Pumain, and M. Barbarosie, Extracellular free potassium and calcium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus., The Journal of Physiology, vol.493, issue.3, pp.493-707, 1996.
DOI : 10.1113/jphysiol.1996.sp021416

G. Biagini, M. D-'antuono, V. Tancredi, R. Motalli, J. Louvel et al., Thalamocortical connectivity in a rat brain slice preparation: participation of the ventrobasal complex to synchronous activities, Thalamus and Related Systems, pp.169-179, 2001.
DOI : 10.1017/S1472928801000164

M. Bikson, R. Id-bihi, M. Vreugdenhil, R. Kohling, J. E. Fox et al., Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro, Neuroscience, vol.115, issue.1, pp.251-261, 2002.
DOI : 10.1016/S0306-4522(02)00320-2

J. Breustedt, T. Gloveli, and U. Heinemann, Far field effects of seizure like events induced by application of 4-AP in combined entorhinal cortex hippocampal slices, Brain Research, vol.956, issue.1, pp.173-177, 2002.
DOI : 10.1016/S0006-8993(02)03541-2

T. Budde, L. Caputi, T. Kanyshkova, R. Staak, C. Abrahamczik et al., Impaired Regulation of Thalamic Pacemaker Channels through an Imbalance of Subunit Expression in Absence Epilepsy, Journal of Neuroscience, vol.25, issue.43, pp.9871-9882
DOI : 10.1523/JNEUROSCI.2590-05.2005

G. Chapouthier, J. M. Launay, P. Venault, C. Breton, P. L. Roubertoux et al., Genetic selection of mouse lines differing in sensitivity to a benzodiazepine receptor inverse agonist, Brain Research, vol.787, issue.1, pp.85-90, 1998.
DOI : 10.1016/S0006-8993(97)01483-2

M. Chipaux, S. Charpier, and P. O. Polack, Chloride-mediated inhibition of the ictogenic neurones initiating genetically-determined absence seizures, Neuroscience, vol.192, pp.642-51, 2011.
DOI : 10.1016/j.neuroscience.2011.06.037

A. M. Coenen and E. L. Van-luijtelaar, Genetic animal models for absence epilepsy: a review of the WAG/Rij strain of rats, Behavior Genetics, vol.33, issue.6, pp.635-655, 2003.
DOI : 10.1023/A:1026179013847

D. F. Condorelli, A. Trovato-salinaro, G. Mudo, M. B. Mirone, and N. Belluardo, Cellular expression of connexins in the rat brain: neuronal localization, effects of kainate-induced seizures and expression in apoptotic neuronal cells, European Journal of Neuroscience, vol.929, issue.7, pp.1807-1827, 2003.
DOI : 10.1016/S0306-4522(99)00226-2

V. Crunelli and N. Leresche, CHILDHOOD ABSENCE EPILEPSY: GENES, CHANNELS, NEURONS AND NETWORKS, Nature Reviews Neuroscience, vol.21, issue.5, pp.371-382, 2002.
DOI : 10.1074/jbc.M109404200

L. Danober, C. Deransart, A. Depaulis, M. Vergnes, and C. Marescaux, Pathophysiological mechanisms of genetic absence epilepsy in the rat, Progress in Neurobiology, vol.55, issue.1, pp.27-57, 1998.
DOI : 10.1016/S0301-0082(97)00091-9

D. Antuono, M. Inaba, Y. Biagini, G. , D. Arcangelo et al., Synaptic hyperexcitability of deep layer neocortical cells in a genetic model of absence seizures, Genes, Brain and Behavior, vol.424, issue.1, pp.73-84, 2006.
DOI : 10.1111/j.1601-183X.2005.00146.x

D. 'arcangelo, G. D-'antuono, M. Biagini, G. Warren, R. Tancredi et al., Thalamocortical oscillations in a genetic model of absence seizures, European Journal of Neuroscience, vol.23, issue.12, pp.2383-2393, 2002.
DOI : 10.1046/j.1460-9568.2002.02411.x

J. S. Davidson, I. M. Baumgarten, and E. H. Harley, Reversible inhibition of intercellular junctional communication by glycyrrhetinic acid, Biochemical and Biophysical Research Communications, vol.134, issue.1, pp.29-36, 1986.
DOI : 10.1016/0006-291X(86)90522-X

G. Dougalis, A. Lees, G. Ganellin, and C. R. , The sleep lipid oleamide may represent an endogenous anticonvulsant: an in vitro comparative study in the 4-aminopyridine rat brain-slice model, Neuropharmacology, vol.46, issue.4, pp.541-554, 2004.
DOI : 10.1016/j.neuropharm.2003.10.011

C. G. Fonseca, C. R. Green, and L. F. Nicholson, Upregulation in astrocytic connexin 43 gap junction levels may exacerbate generalized seizures in mesial temporal lobe epilepsy, Brain Research, vol.929, issue.1, 2002.
DOI : 10.1016/S0006-8993(01)03289-9

Z. Gajda, E. Gyengesi, E. Hermesz, K. S. Ali, and M. Szente, Involvement of Gap Junctions in the Manifestation and Control of the Duration of Seizures in Rats In Vivo, Epilepsia, vol.503, issue.12, pp.1596-1600, 2003.
DOI : 10.1016/S0304-3940(01)01530-0

M. Galarreta and S. Hestrin, A network of fast-spiking cells in the neocortex connected by electrical synapses, Nature, vol.402, pp.72-75, 1999.

P. Gareri, D. Condorelli, N. Belluardo, E. Russo, A. Loiacono et al., Anticonvulsant effects of carbenoxolone in genetically epilepsy prone rats (GEPRs), Neuropharmacology, vol.47, issue.8, pp.1205-1216, 2004.
DOI : 10.1016/j.neuropharm.2004.08.021

J. R. Gibson, M. Beierlein, and B. W. Connors, Two networks of electrically coupled inhibitory neurons in neocortex, Nature, vol.402, pp.75-79, 1999.

S. Gigout, J. Louvel, and R. Pumain, Study of the efficacy of thalamo-cortical and corticothalamic relationships in a genetic model of absence-epilepsy (GAERS). Epilepsies, pp.73-81, 2005.

S. Gigout, J. Louvel, H. Kawasaki, M. D-'antuono, V. Armand et al., Effects of gap junction blockers on human neocortical synchronization, Neurobiology of Disease, vol.22, issue.3, pp.496-508, 2006.
DOI : 10.1016/j.nbd.2005.12.011

S. N. Hoffman and D. A. Prince, Epileptogenesis in immature neocortical slices induced by 4-aminopyridine, Developmental Brain Research, vol.85, issue.1, pp.64-70, 1995.
DOI : 10.1016/0165-3806(94)00196-7

J. R. Huguenard and D. A. Prince, Intrathalamic rhythmicity studied in vitro: nominal Tcurrent modulation causes robust antioscillatory effects, J.Neurosci, vol.14, pp.5485-5502, 1994.

Y. Inaba and M. Avoli, Volume-conducted epileptiform events between adjacent necortical slices in an interface tissue chamber, Journal of Neuroscience Methods, vol.151, issue.2, pp.287-290, 2006.
DOI : 10.1016/j.jneumeth.2005.07.008

P. H. Jellinck, C. Monder, B. S. Mcewen, and R. R. Sakai, Differential inhibition of 11??-hydroxysteroid dehydrogenase by carbenoxolone in rat brain regions and peripheral tissues, The Journal of Steroid Biochemistry and Molecular Biology, vol.46, issue.2, pp.209-213, 1993.
DOI : 10.1016/0960-0760(93)90296-9

G. R. Juszczak and A. H. Swiergiel, Properties of gap junction blockers and their behavioural, cognitive and electrophysiological effects: animal and human studies. Progress in neuropsychopharmacology & biological psychiatry, pp.181-98, 2009.

R. Kohling, S. J. Gladwell, E. Bracci, M. Vreugdenhil, and J. G. Jefferys, Prolonged epileptiform bursting induced by 0-Mg2+ in rat hippocampal slices depends on gap junctional coupling, Neuroscience, vol.105, issue.3, pp.579-587, 2001.
DOI : 10.1016/S0306-4522(01)00222-6

S. Lindstrom and A. Wrobel, Frequency dependent corticofugal excitation of principal cells in the cat's dorsal lateral geniculate nucleus, Experimental Brain Research, vol.32, issue.2, pp.313-318, 1990.
DOI : 10.1007/BF00608240

X. B. Liu and E. G. Jones, Fine structural localization of connexin-36 immunoreactivity in mouse cerebral cortex and thalamus, The Journal of Comparative Neurology, vol.3, issue.4, pp.457-467, 2003.
DOI : 10.1002/cne.10901

V. Lopantsev and M. Avoli, Participation of GABAA-mediated inhibition in ictallike discharges in the rat entorhinal cortex, J.Neurophysiol, vol.79, pp.352-360, 1998.

H. J. Luhmann, T. Mittmann, G. Van-luijtelaar, and U. Heinemann, Impairment of intracortical GABAergic inhibition in a rat model of absence epilepsy, Epilepsy Research, vol.22, issue.1, pp.43-51, 1995.
DOI : 10.1016/0920-1211(95)00032-6

N. Maier, M. Guldenagel, G. Sohl, H. Siegmund, K. Willecke et al., Reduction of high-frequency network oscillations (ripples) and pathological network discharges in hippocampal slices from connexin 36-deficient mice, The Journal of Physiology, vol.15, issue.2, pp.521-528, 2002.
DOI : 10.1113/jphysiol.2002.017624

C. Marescaux, M. Vergnes, L. H. Jensen, E. Petersen, A. Depaulis et al., Bidirectional effects of beta-carbolines in rats with spontaneous petit mal-like scizures, Brain Research Bulletin, vol.19, issue.3, pp.327-335, 1987.
DOI : 10.1016/0361-9230(87)90101-8

H. Meeren, G. Van-luijtelaar, F. Lopes-da-silva, and A. Coenen, Evolving Concepts on the Pathophysiology of Absence Seizures, Archives of Neurology, vol.62, issue.3, pp.371-377, 2005.
DOI : 10.1001/archneur.62.3.371

K. Mishima, Facilitatory and Inhibitory Processes in the Thalamic Ventrobasal Nucleus of the Rat., The Japanese Journal of Physiology, vol.42, issue.2, pp.193-210, 1992.
DOI : 10.2170/jjphysiol.42.193

K. Mishima and M. Ohta, Reappraisal of the Corticothalamic and Thalamocortical Interactions that Contribute to the Augmenting Response in the Rat., The Japanese Journal of Physiology, vol.42, issue.2, pp.211-221, 1992.
DOI : 10.2170/jjphysiol.42.211

T. Nakase and C. C. Naus, Gap junctions and neurological disorders of the central nervous system, Biochimica et Biophysica Acta (BBA) - Biomembranes, vol.1662, issue.1-2, pp.149-158, 2004.
DOI : 10.1016/j.bbamem.2004.01.009

C. C. Naus, J. F. Bechberger, and D. L. Paul, Gap junction gene expression in human seizure disorder, Experimental Neurology, vol.111, issue.2, pp.198-203, 1991.
DOI : 10.1016/0014-4886(91)90007-Y

G. Paxinos and C. Watson, The rat brain, in stereotaxic coordinates, 1988.

P. Perreault and M. Avoli, 4-aminopyridine-induced epileptiform activity and a GABAmediated long-lasting depolarization in the rat hippocampus, J.Neurosci, vol.12, pp.104-115, 1992.

D. Pinault, Cellular interactions in the rat somatosensory thalamocortical system during normal and epileptic 5-9 Hz oscillations, The Journal of Physiology, vol.17, issue.suppl., pp.881-905, 2003.
DOI : 10.1113/jphysiol.2003.046573

URL : https://hal.archives-ouvertes.fr/inserm-00560829

P. O. Polack, I. Guillemain, E. Hu, C. Deransart, A. Depaulis et al., Deep Layer Somatosensory Cortical Neurons Initiate Spike-and-Wave Discharges in a Genetic Model of Absence Seizures, Journal of Neuroscience, vol.27, issue.24, pp.6590-6599, 2007.
DOI : 10.1523/JNEUROSCI.0753-07.2007

URL : https://hal.archives-ouvertes.fr/inserm-00385581

P. O. Polack, S. Mahon, M. Chavez, and S. Charpier, Inactivation of the Somatosensory Cortex Prevents Paroxysmal Oscillations in Cortical and Related Thalamic Neurons in a Genetic Model of Absence Epilepsy, Cerebral Cortex, vol.19, issue.9, pp.2078-91, 2009.
DOI : 10.1093/cercor/bhn237

URL : https://hal.archives-ouvertes.fr/hal-00805445

E. Proulx, Y. Leshchenko, L. Kokarovtseva, V. Khokhotva, M. Beheiry et al., Functional contribution of specific brain areas to absence seizures: role of thalamic gap-junctional coupling, European Journal of Neuroscience, vol.92, issue.Suppl. 7, pp.489-496, 2006.
DOI : 10.1111/j.1460-9568.2005.04558.x

D. Rinaldi, A. Depaulis, and B. Martin, BR/Orl and BS/Orl mice: two mouse models for human absence-epilepsy and resistance to absence-epilepsy, Epilepsies, vol.4, pp.245-248, 2002.

F. M. Ross, P. Gwyn, D. Spanswick, and S. N. Davies, Carbenoxolone depresses spontaneous epileptiform activity in the CA1 region of rat hippocampal slices, Neuroscience, vol.100, issue.4, pp.789-796, 2000.
DOI : 10.1016/S0306-4522(00)00346-8

N. Rouach, M. Segal, A. Koulakoff, C. Giaume, and E. Avignone, Carbenoxolone Blockade of Neuronal Network Activity in Culture is not Mediated by an Action on Gap Junctions, The Journal of Physiology, vol.31, issue.3, 2003.
DOI : 10.1113/jphysiol.2003.053439

M. Salami, C. Itami, T. Tsumoto, and F. Kimura, Change of conduction velocity by regional myelination yields constant latency irrespective of distance between thalamus and cortex, Proceedings of the National Academy of Sciences, vol.100, issue.10, 2003.
DOI : 10.1073/pnas.0937380100

D. Schmitz, S. Schuchmann, A. Fisahn, A. Draguhn, E. H. Buhl et al., Axo-Axonal Coupling, Neuron, vol.31, issue.5, pp.831-840, 2001.
DOI : 10.1016/S0896-6273(01)00410-X

URL : http://doi.org/10.1016/s0896-6273(01)00410-x

J. F. Staiger, R. Kotter, K. Zilles, and H. J. Luhmann, Connectivity in the somatosensory cortex of the adolescent rat: an in vitro biocytin study, Anatomy and Embryology, vol.199, issue.4, pp.357-365, 1999.
DOI : 10.1007/s004290050234

M. Steriade and D. Contreras, Spike-wave complexes and fast components of cortically generated seizures. I. Role of neocortex and thalamus, J.Neurophysiol, vol.80, pp.1439-1455, 1998.

A. K. Streit, C. Derst, S. Wegner, U. Heinemann, R. K. Zahn et al., RNA editing of Kv1.1 channels may account for reduced ictogenic potential of 4-aminopyridine in chronic epileptic rats, Epilepsia, vol.29, issue.3, pp.645-648, 2011.
DOI : 10.1111/j.1528-1167.2011.02986.x

V. Tancredi, G. Biagini, M. D-'antuono, J. Louvel, R. Pumain et al., Spindle-like thalamocortical synchronization in a rat brain slice preparation, J.Neurophysiol, vol.84, pp.1093-1097, 2000.

S. Temereanca and D. J. Simons, Local Field Potentials and the Encoding of Whisker Deflections by Population Firing Synchrony in Thalamic Barreloids, Journal of Neurophysiology, vol.89, issue.4, pp.2137-2145, 2003.
DOI : 10.1152/jn.00582.2002

R. D. Traub, R. Bibbig, A. Piechotta, R. Draguhn, and D. Schmitz, Synaptic and nonsynaptic contributions to giant ipsps and ectopic spikes induced by 4-aminopyridine in the hippocampus in vitro, J.Neurophysiol, vol.85, pp.1246-1256, 2001.

M. Uusisaari, S. Smirnov, J. Voipio, and K. Kaila, Spontaneous epileptiform activity mediated by GABAA receptors and gap junctions in the rat hippocampal slice following long-term exposure to GABAB antagonists, Neuropharmacology, vol.43, issue.4, pp.563-572, 2002.
DOI : 10.1016/S0028-3908(02)00156-9

M. Vergnes, A. Boehrer, X. He, H. Greney, M. Dontenwill et al., Differential sensitivity to inverse agonists of GABA(A)/benzodiazepine receptors in rats, 2001.