R. Stupp, M. Hegi, W. Mason, M. Van-den-bent, M. Taphoorn et al., Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial, The Lancet Oncology, vol.10, issue.5, pp.459-66, 2009.
DOI : 10.1016/S1470-2045(09)70025-7

P. Wen and S. Kesari, Malignant Gliomas in Adults, New England Journal of Medicine, vol.359, issue.5, pp.492-507, 2008.
DOI : 10.1056/NEJMra0708126

A. Giese, T. Kucinski, U. Knopp, R. Goldbrunner, W. Hamel et al., Pattern of Recurrence following Local Chemotherapy with Biodegradable Carmustine (BCNU) Implants in Patients with Glioblastoma, Journal of Neuro-Oncology, vol.66, issue.3, pp.351-60, 2004.
DOI : 10.1023/B:NEON.0000014539.90077.db

F. Lefranc, J. Brotchi, and R. Kiss, Possible Future Issues in the Treatment of Glioblastomas: Special Emphasis on Cell Migration and the Resistance of Migrating Glioblastoma Cells to Apoptosis, Journal of Clinical Oncology, vol.23, issue.10, pp.2411-2433, 2005.
DOI : 10.1200/JCO.2005.03.089

B. Liang, A. Thornton, J. Sandler, H. Greenberg, H. Iacob et al., Malignant astrocytomas: focal tumor recurrence after focal external beam radiation therapy Current data and strategy in glioblastoma multiforme An integrated genomic analysis of human glioblastoma multiforme, J Neurosurg J Med Life Science, vol.7523218, pp.559-63386, 1991.

M. Vitucci, D. Hayes, C. Miller, A. Carlsson, O. Persson et al., Gene expression profiling of gliomas: merging genomic and histopathological classification for personalised therapy Plasma proteome profiling reveals biomarker patterns associated with prognosis and therapy selection in glioblastoma multiforme patients, Br J Cancer Proteomics Clin Appl, vol.1044, pp.545-53591, 2010.

E. Com, A. Clavreul, M. Lagarrigue, S. Michalak, P. Menei et al., Quantitative proteomic Isotope-Coded Protein Label (ICPL) analysis reveals alteration of several functional processes in the glioblastoma, Journal of Proteomics, vol.75, issue.13, pp.3898-913, 2012.
DOI : 10.1016/j.jprot.2012.04.034
URL : https://hal.archives-ouvertes.fr/hal-00877756

S. Niclou, F. Fack, and U. Rajcevic, Glioma proteomics: Status and perspectives, Journal of Proteomics, vol.73, issue.10, pp.1823-1861, 2010.
DOI : 10.1016/j.jprot.2010.03.007

A. Khalil, Biomarker discovery: A proteomic approach for brain cancer profiling, Cancer Science, vol.250, issue.2, pp.201-214, 2007.
DOI : 10.1038/nrn1518

A. Schmidt, J. Kellermann, and F. Lottspeich, A novel strategy for quantitative proteomics using isotope-coded protein labels, PROTEOMICS, vol.3, issue.1, pp.4-15, 2005.
DOI : 10.1002/pmic.200400873

J. Kellermann, ICPL???Isotope-Coded Protein Label, Methods Mol Biol, vol.424, pp.113-136, 2008.
DOI : 10.1007/978-1-60327-064-9_10
URL : http://hdl.handle.net/11858/00-001M-0000-0010-5E26-4

F. Lottspeich and J. Kellermann, ICPL Labeling Strategies for Proteome Research, Methods Mol Biol, vol.753, pp.55-64, 2011.
DOI : 10.1007/978-1-61779-148-2_4
URL : http://hdl.handle.net/11858/00-001M-0000-0010-5514-0

J. Schwartzentruber, A. Korshunov, X. Liu, D. Jones, E. Pfaff et al., Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma, Nature, vol.16, issue.7384, pp.226-257, 2012.
DOI : 10.1038/nature10833

D. Sturm, H. Witt, V. Hovestadt, D. Khuong-quang, D. Jones et al., Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma, Cancer Cell, vol.22, issue.4, pp.425-462, 2012.
DOI : 10.1016/j.ccr.2012.08.024

T. Sorlie, C. Perou, R. Tibshirani, T. Aas, S. Geisler et al., Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications, Proceedings of the National Academy of Sciences, vol.98, issue.19, pp.10869-74, 2001.
DOI : 10.1073/pnas.191367098

D. Chin, G. Boyle, R. Williams, K. Ferguson, N. Pandeya et al., Alpha B-Crystallin, a New Independent Marker for Poor Prognosis in Head and Neck Cancer, The Laryngoscope, vol.100, issue.7, pp.1239-1281, 2005.
DOI : 10.1097/01.MLG.0000164715.86240.55

J. Yaung, R. Kannan, E. Wawrousek, C. Spee, P. Sreekumar et al., Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia, Experimental Eye Research, vol.86, issue.2, pp.355-65, 2008.
DOI : 10.1016/j.exer.2007.11.007

P. Louapre, J. Grongnet, R. Tanguay, and J. David, Effects of hypoxia on stress proteins in the piglet heart at birth, Cell Stress & Chaperones, vol.894, issue.1, pp.17-23, 2005.
DOI : 10.1379/CSC-74R.1

A. Dimberg, S. Rylova, L. Dieterich, A. Olsson, P. Schiller et al., ??B-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis, Blood, vol.111, issue.4, pp.2015-2038, 2008.
DOI : 10.1182/blood-2007-04-087841

S. Han, C. Shin, S. Park, S. Rhyu, J. Park et al., Differential Expression of Activating Transcription Factor-2 and c-Jun in the Immature and Adult Rat Hippocampus Following Lithium-Pilocarpine Induced Status Epilepticus, Yonsei Medical Journal, vol.50, issue.2, pp.200-205, 2009.
DOI : 10.3349/ymj.2009.50.2.200

C. Houser, N. Zhang, Z. Peng, C. Huang, and Y. Cetina, Neuroanatomical clues to altered neuronal activity in epilepsy: From ultrastructure to signaling pathways of dentate granule cells, Epilepsia, vol.25, issue.Suppl. 12
DOI : 10.1111/j.1528-1167.2012.03477.x

A. Clavreul, A. Etcheverry, A. Chassevent, V. Quillien, T. Avril et al., Isolation of a new cell population in the glioblastoma microenvironment, Journal of Neuro-Oncology, vol.68, issue.3, pp.493-504, 2012.
DOI : 10.1007/s11060-011-0701-7
URL : https://hal.archives-ouvertes.fr/inserm-00626532

K. Skold, M. Svensson, M. Norrman, B. Sjogren, P. Svenningsson et al., The significance of biochemical and molecular sample integrity in brain proteomics and peptidomics: Stathmin 2-20 and peptides as sample quality indicators, PROTEOMICS, vol.4, issue.24, pp.4445-56, 2007.
DOI : 10.1002/pmic.200700142

B. Collet, N. Guitton, S. Saikali, A. T. Pineau, C. Hamlat et al., Differential analysis of glioblastoma multiforme proteome by a 2D-DIGE approach, Proteome Science, vol.9, issue.1, p.16, 2011.
DOI : 10.1016/j.ab.2010.02.036
URL : https://hal.archives-ouvertes.fr/inserm-00585020

K. Melchior, A. Tholey, S. Heisel, A. Keller, H. Lenhof et al., Proteomic Study of Human Glioblastoma Multiforme Tissue Employing Complementary Two-Dimensional Liquid Chromatography- and Mass Spectrometry-Based Approaches, Journal of Proteome Research, vol.8, issue.10, pp.4604-4618, 2009.
DOI : 10.1021/pr900420b

C. Park, J. Jung, M. Moon, Y. Kim, J. Kim et al., Tissue Expression of Manganese Superoxide Dismutase Is a Candidate Prognostic Marker for Glioblastoma, Oncology, vol.77, issue.3-4, pp.178-81, 2009.
DOI : 10.1159/000231888

D. Mustafa, P. Burgers, L. Dekker, H. Charif, M. Titulaer et al., Identification of Glioma Neovascularization-related Proteins by Using MALDI-FTMS and Nano-LC Fractionation to Microdissected Tumor Vessels, Molecular & Cellular Proteomics, vol.6, issue.7, pp.1147-57, 2007.
DOI : 10.1074/mcp.M600295-MCP200

M. Furuta, R. Weil, A. Vortmeyer, S. Huang, J. Lei et al., Protein patterns and proteins that identify subtypes of glioblastoma multiforme, Oncogene, vol.23, issue.40, pp.6806-6820, 2004.
DOI : 10.1038/sj.onc.1207770

S. Schwartz, R. Weil, R. Thompson, Y. Shyr, J. Moore et al., Proteomic-based prognosis of brain tumor patients using direct-tissue matrix-assisted laser desorption ionization mass spectrometry, Cancer Res, vol.65, pp.7674-81, 2005.

V. Chumbalkar, C. Subhashini, V. Dhople, C. Sundaram, M. Jagannadham et al., Differential protein expression in human gliomas and molecular insights, PROTEOMICS, vol.87, issue.4, pp.1167-77, 2005.
DOI : 10.1002/pmic.200401202

Y. Iwadate, T. Sakaida, T. Hiwasa, Y. Nagai, H. Ishikura et al., Molecular Classification and Survival Prediction in Human Gliomas Based on Proteome Analysis, Cancer Research, vol.64, issue.7, pp.2496-501, 2004.
DOI : 10.1158/0008-5472.CAN-03-1254

S. Schwartz, R. Weil, M. Johnson, S. Toms, and R. Caprioli, Protein Profiling in Brain Tumors Using Mass Spectrometry: Feasibility of a New Technique for the Analysis of Protein Expression, Clinical Cancer Research, vol.10, issue.3, pp.981-988, 2004.
DOI : 10.1158/1078-0432.CCR-0927-3

M. Hiratsuka, T. Inoue, T. Toda, N. Kimura, Y. Shirayoshi et al., Proteomics-based identification of differentially expressed genes in human gliomas: down-regulation of SIRT2 gene, Biochemical and Biophysical Research Communications, vol.309, issue.3, pp.558-66, 2003.
DOI : 10.1016/j.bbrc.2003.08.029

S. Hobbs, G. Shi, R. Homer, G. Harsh, S. Atlas et al., Magnetic resonance image-guided proteomics of human glioblastoma multiforme, Journal of Magnetic Resonance Imaging, vol.407, issue.5, pp.530-536, 2003.
DOI : 10.1002/jmri.10395