A. Jemal, F. Bray, M. Center, J. Ferlay, and E. Ward, Global cancer statistics, CA: A Cancer Journal for Clinicians, vol.82, issue.19 suppl, pp.69-90, 2011.
DOI : 10.3322/caac.20107

D. Palli, Epidemiology of gastric cancer: an evaluation of available evidence, J Gastroenterol, vol.35, pp.84-89, 2000.

D. Compare, R. A. Nardone, and G. , Risk factors in gastric cancer, Eur Rev Med Pharmacol Sci, vol.14, pp.302-308, 2010.

C. Diaz-ruiz, B. Montaner, and R. Perez-tomas, Prodigiosin induces cell death and morphological changes indicative of apoptosis in gastric cancer cell line HGT-1, Histol Histopathol, vol.16, pp.415-421, 2001.

H. Lin, J. Chen, C. Huang, and C. Wang, Apoptotic effect of 3,4-dihydroxybenzoic acid on human gastric carcinoma cells involving JNK/p38 MAPK signaling activation, International Journal of Cancer, vol.7, issue.11, pp.2306-2316, 2007.
DOI : 10.1002/ijc.22571

Z. Ran, Q. Xu, J. Tong, and S. Xiao, activation of the mitochondrial pathway, World Journal of Gastroenterology, vol.13, issue.31, pp.4255-4259, 2007.
DOI : 10.3748/wjg.v13.i31.4255

J. Kim, S. Kim, K. Lee, and H. Lee, Arginine deiminase originating from Lactococcus lactis ssp. lactis American Type Culture Collection (ATCC) 7962 induces G1-phase cell-cycle arrest and apoptosis in SNU-1 stomach adenocarcinoma cells, British Journal of Nutrition, vol.98, issue.10, pp.1469-1476, 2009.
DOI : 10.1007/s10637-007-9105-0

S. Kim, J. Kim, K. Lee, and H. Lee, Lactococcus lactis ssp. lactis Inhibits the Proliferation of SNU-1 Human Stomach Cancer Cells through Induction of G0/G1 Cell Cycle Arrest and Apoptosis via p53 and p21 Expression, Annals of the New York Academy of Sciences, vol.2, issue.1, pp.270-275, 2009.
DOI : 10.1111/j.1749-6632.2009.04721.x

F. Experts and . Who, Probiotics in food: health and nutritional properties and guidelines for evaluation, 2006.

M. Kumar, A. Kumar, R. Nagpal, D. Mohania, and P. Behare, Cancer-preventing attributes of probiotics: an update, International Journal of Food Sciences and Nutrition, vol.73, issue.3, pp.473-496, 2010.
DOI : 10.1080/01635588309513793

J. Wong, R. De-souza, C. Kendall, A. Emam, and D. Jenkins, Colonic Health: Fermentation and Short Chain Fatty Acids, Journal of Clinical Gastroenterology, vol.40, issue.3, pp.235-243, 2006.
DOI : 10.1097/00004836-200603000-00015

M. Bordonaro, D. Lazarova, and A. Sartorelli, Butyrate and Wnt signaling: a possible solution to the puzzle of dietary fiber and colon cancer risk?, Cell Cycle, vol.7, issue.9, pp.1178-1183, 2008.
DOI : 10.4161/cc.7.9.5818

G. Matthews, G. Howarth, and R. Butler, Short-chain fatty acid modulation of apoptosis in the kato III human gastric carcinoma cell line, Cancer Biology & Therapy, vol.6, issue.7, pp.1051-1057, 2007.
DOI : 10.4161/cbt.6.7.4318

L. Tsai, M. Hung, G. Chang, and T. Chang, Apoptosis induced by the sodium butyrate in human gastric cancer TMK-1 cells, Anticancer Res, vol.20, pp.2441-2448, 2000.

J. Yan and Y. Xu, Tributyrin inhibits human gastric cancer SGC-7901 cell growth by inducing apoptosis and DNA synthesis arrest, World Journal of Gastroenterology, vol.9, issue.4, pp.660-664, 2003.
DOI : 10.3748/wjg.v9.i4.660
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611423

S. Elmore, Apoptosis: A Review of Programmed Cell Death, Toxicologic Pathology, vol.135, issue.2, pp.495-516, 2007.
DOI : 10.1016/S0092-8674(00)81382-3

K. Kurosaka, M. Takahashi, N. Watanabe, and Y. Kobayashi, Silent Cleanup of Very Early Apoptotic Cells by Macrophages, The Journal of Immunology, vol.171, issue.9, pp.4672-4679, 2003.
DOI : 10.4049/jimmunol.171.9.4672

J. Savill and V. Fadok, Corpse clearance defines the meaning of cell death, Nature, vol.407, issue.6805, pp.784-788, 2000.
DOI : 10.1038/35037722

G. Jan, A. Belzacq, D. Haouzi, A. Rouault, and D. Metivier, Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondria, Cell Death and Differentiation, vol.9, issue.2, pp.179-188, 2002.
DOI : 10.1038/sj.cdd.4400935
URL : https://hal.archives-ouvertes.fr/hal-00088749

A. Lan, D. Lagadic-gossmann, C. Lemaire, and C. Brenner, Acidic extracellular pH shifts colorectal cancer cell death from apoptosis to necrosis upon exposure to propionate and acetate, major end-products of the human probiotic propionibacteria, Apoptosis, vol.58, issue.3, pp.573-591, 2007.
DOI : 10.1007/s10495-006-0010-3
URL : https://hal.archives-ouvertes.fr/hal-00690344

C. Hervé, M. Fondrevez, A. Cheron, and F. Barloy-hubler, Transcarboxylase mRNA: A marker which evidences P. freudenreichii survival and metabolic activity during its transit in the human gut, International Journal of Food Microbiology, vol.113, issue.3, pp.303-314, 2007.
DOI : 10.1016/j.ijfoodmicro.2006.08.013

A. Lan, A. Bruneau, C. Philippe, V. Rochet, and A. Rouault, Survival and metabolic activity of selected strains of Propionibacterium freudenreichii in the gastrointestinal tract of human microbiota-associated rats, British Journal of Nutrition, vol.97, issue.04, pp.714-724, 2007.
DOI : 10.1017/S0007114507433001

A. Lan, A. Bruneau, M. Bensaada, C. Philippe, and P. Bellaud, Increased induction of apoptosis by Propionibacterium freudenreichii TL133 in colonic mucosal crypts of human microbiota-associated rats treated with 1,2-dimethylhydrazine, British Journal of Nutrition, vol.127, issue.06, p.2, 2008.
DOI : 10.1079/BJN2001403
URL : https://hal.archives-ouvertes.fr/hal-01454096

P. Leverrier, Y. Fremont, A. Rouault, and P. Boyaval, In vitro tolerance to digestive stresses of propionibacteria: influence of food matrices, Food Microbiology, vol.22, issue.1, pp.11-18, 2005.
DOI : 10.1016/j.fm.2004.05.003
URL : https://hal.archives-ouvertes.fr/hal-01453978

M. Saxelin, A. Lassig, H. Karjalainen, S. Tynkkynen, and A. Surakka, Persistence of probiotic strains in the gastrointestinal tract when administered as capsules, yoghurt, or cheese, International Journal of Food Microbiology, vol.144, issue.2, pp.293-300, 2010.
DOI : 10.1016/j.ijfoodmicro.2010.10.009

A. Thierry, S. Deutsch, H. Falentin, M. Dalmasso, and F. Cousin, New insights into physiology and metabolism of Propionibacterium freudenreichii, International Journal of Food Microbiology, vol.149, issue.1, pp.19-27, 2011.
DOI : 10.1016/j.ijfoodmicro.2011.04.026
URL : https://hal.archives-ouvertes.fr/hal-01454137

C. Bortner, N. Oldenburg, and J. Cidlowski, The role of DNA fragmentation in apoptosis, Trends in Cell Biology, vol.5, issue.1, pp.21-26, 1995.
DOI : 10.1016/S0962-8924(00)88932-1

T. Chou and P. Talalay, Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors, Advances in Enzyme Regulation, vol.22, pp.27-55, 1984.
DOI : 10.1016/0065-2571(84)90007-4

F. Cousin, D. Mater, and B. Foligné, Dairy propionibacteria as human probiotics: A review of recent evidence, Dairy Science & Technology, vol.106, pp.1-26, 2011.
DOI : 10.1051/dst/2010032
URL : https://hal.archives-ouvertes.fr/hal-00868601

D. Sohn, K. Schulze-osthoff, and R. Janicke, Caspase-8 Can Be Activated by Interchain Proteolysis without Receptor-triggered Dimerization during Drug-induced Apoptosis, Journal of Biological Chemistry, vol.280, issue.7, pp.5267-5273, 2005.
DOI : 10.1074/jbc.M408585200

U. Fischer, C. Stroh, and K. Schulze-osthoff, Unique and overlapping substrate specificities of caspase-8 and caspase-10, Oncogene, vol.290, pp.152-159, 2005.
DOI : 10.1038/sj.onc.1209015

S. Fulda, Caspase-8 in cancer biology and therapy, Cancer Letters, vol.281, issue.2, pp.128-133, 2009.
DOI : 10.1016/j.canlet.2008.11.023

S. Hopkins-donaldson, J. Bodmer, K. Bourloud, C. Brognara, and J. Tschopp, Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis, Cancer Res, vol.60, pp.4315-4319, 2000.

A. Eggert, M. Grotzer, T. Zuzak, B. Wiewrodt, and R. Ho, Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression, Cancer Res, vol.61, pp.1314-1319, 2001.

V. Kaminskyy, O. Surova, A. Vaculova, and B. Zhivotovsky, Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL, Carcinogenesis, vol.32, issue.10, 2011.
DOI : 10.1093/carcin/bgr135

B. Hinnebusch, S. Meng, J. Wu, S. Archer, and R. Hodin, The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation, J Nutr, vol.132, pp.1012-1017, 2002.

M. Grunstein, Histone acetylation in chromatin structure and transcription, Nature, vol.389, issue.6649, pp.349-352, 1997.
DOI : 10.1038/38664

Y. Lu, B. Zhang, Z. Jia, W. Wu, and Z. Lu, Hepatocellular carcinoma HepG2 cell apoptosis and caspase-8 and Bcl-2 expression induced by injectable seed extract of Coix lacryma-jobi, Hepatobiliary & Pancreatic Diseases International, vol.10, issue.3, pp.303-307, 2011.
DOI : 10.1016/S1499-3872(11)60050-7

E. Slee, M. Harte, R. Kluck, B. Wolf, and C. Casiano, Ordering the Cytochrome c???initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9???dependent Manner, The Journal of Cell Biology, vol.109, issue.2, pp.281-292, 1999.
DOI : 10.1016/S0092-8674(00)80501-2

V. Viswanath, Y. Wu, R. Boonplueang, S. Chen, and F. Stevenson, Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease, J Neurosci, vol.21, pp.9519-9528, 2001.

S. Inoue, G. Browne, G. Melino, and G. Cohen, Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway, Cell Death and Differentiation, vol.326, issue.7, pp.1053-1061, 2009.
DOI : 10.1091/mbc.E06-05-0409

D. Aune, R. Lau, D. Chan, R. Vieira, and D. Greenwood, Dairy products and colorectal cancer risk: a systematic review and meta-analysis of cohort studies, Annals of Oncology, vol.23, issue.1, pp.1-9, 2011.
DOI : 10.1093/annonc/mdr269

M. Sanders and M. Marco, Food Formats for Effective Delivery of Probiotics, Annual Review of Food Science and Technology, vol.1, issue.1, pp.65-85, 2010.
DOI : 10.1146/annurev.food.080708.100743

K. Fujita, E. Matsuda, K. Sekine, M. Iigo, and H. Tsuda, Lactoferrin enhances Fas expression and apoptosis in the colon mucosa of azoxymethane-treated rats, Carcinogenesis, vol.25, issue.10, pp.1961-1966, 2004.
DOI : 10.1093/carcin/bgh205

X. Xu, H. Jiang, H. Li, T. Zhang, and Q. Zhou, Apoptosis of stomach cancer cell SGC-7901 and regulation of Akt signaling way induced by bovine lactoferrin, Journal of Dairy Science, vol.93, issue.6, pp.2344-2350, 2010.
DOI : 10.3168/jds.2009-2926

A. De-moreno-de-leblanc and G. Perdigon, The application of probiotic fermented milks in cancer and intestinal inflammation, Proceedings of the Nutrition Society, vol.69, issue.03, pp.421-428, 2010.
DOI : 10.1017/S002966511000159X

A. Thiel, B. Eikmanns, S. Salminen, and A. Ouwehand, In vitro adhesion of propionibacteria to human intestinal mucus, Ital J Food Sci, vol.16, pp.245-253, 2004.

G. Zarate, D. Ambrosini, V. Chaia, A. Gonzalez, and S. , Adhesion of Dairy Propionibacteria to Intestinal Epithelial Tissue In Vitro and In Vivo, Journal of Food Protection, vol.65, issue.3, pp.534-539, 2002.
DOI : 10.4315/0362-028X-65.3.534

E. Myllyluoma, A. Ahonen, R. Korpela, H. Vapaatalo, and E. Kankuri, Effects of Multispecies Probiotic Combination on Helicobacter pylori Infection In Vitro, Clinical and Vaccine Immunology, vol.15, issue.9, pp.1472-1482, 2008.
DOI : 10.1128/CVI.00080-08

C. Baldwin, M. Millette, D. Oth, M. Ruiz, and F. Luquet, Mix Sensitize Colorectal Tumoral Cells to 5-Fluorouracil-Induced Apoptosis, Nutrition and Cancer, vol.16, issue.3, pp.371-378, 2010.
DOI : 10.1007/s12272-001-1180-y
URL : https://hal.archives-ouvertes.fr/pasteur-00819609

D. Litvak, K. Hwang, B. Evers, and C. Townsend, Induction of apoptosis in human gastric cancer by sodium butyrate, Anticancer Res, vol.20, pp.779-784, 2000.

D. Coradini, C. Pellizzaro, D. Marimpietri, C. Abolafio, and M. Daidone, Sodium butyrate modulates cell cycle-related proteins in HT29 human colonic adenocarcinoma cells, Cell Proliferation, vol.41, issue.3, pp.139-146, 2000.
DOI : 10.1097/00000658-199806000-00016

D. Litvak, B. Evers, K. Hwang, M. Hellmich, and T. Ko, Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21Waf1/Cip1 and p27Kip1, Surgery, vol.124, issue.2, pp.161-169, 1998.
DOI : 10.1016/S0039-6060(98)70116-3

L. Prisciandaro, M. Geier, R. Butler, A. Cummins, and G. Howarth, Evidence Supporting the use of Probiotics for the Prevention and Treatment of Chemotherapy-Induced Intestinal Mucositis, Critical Reviews in Food Science and Nutrition, vol.71, issue.3, pp.239-247, 2011.
DOI : 10.1158/1535-7163.MCT-07-0113

M. Michalski, N. Leconte, V. Briard-bion, J. Fauquant, and J. Maubois, Microfiltration of Raw Whole Milk to Select Fractions with Different Fat Globule Size Distributions: Process Optimization and Analysis, Journal of Dairy Science, vol.89, issue.10, pp.3778-3790, 2006.
DOI : 10.3168/jds.S0022-0302(06)72419-5
URL : https://hal.archives-ouvertes.fr/hal-01453960

C. Laboisse, C. Augeron, M. Couturierturpin, C. Gespach, and A. Cheret, Characterization of a newly established human gastric cancer cell line HGT-1 bearing histamine H-2-receptors, Cancer Res, vol.42, pp.1541-1548, 1982.

L. Gibot, J. Follet, J. Metges, P. Auvray, and B. Simon, Human caspase 7 is positively controlled by SREBP-1 and SREBP-2, Biochemical Journal, vol.26, issue.3, pp.473-483, 2009.
DOI : 10.1038/sj.onc.1208524
URL : https://hal.archives-ouvertes.fr/hal-00479110

M. Dimanche-boitrel, H. Pelletier, P. Genne, J. Petit, and C. Legrimellec, Confluence-dependent resistance in human colon cancer cells: Role of reduced drug accumulation and low intrinsic chemosensitivity of resting cells, International Journal of Cancer, vol.111, issue.5, pp.677-682, 1992.
DOI : 10.1002/ijc.2910500502

F. Verrier, A. Deniaud, M. Lebras, D. Metivier, and G. Kroemer, Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis, Oncogene, vol.23, issue.49, pp.8049-8064, 2004.
DOI : 10.1038/sj.onc.1208001

O. Meurette, L. Lefeuvre-orfila, A. Rebillard, D. Lagadic-gossmann, and M. Dimanche-boitrel, Role of Intracellular Glutathione in Cell Sensitivity to the Apoptosis Induced by Tumor Necrosis Factor ??-Related Apoptosis-Inducing Ligand/Anticancer Drug Combinations, Clinical Cancer Research, vol.11, issue.8, pp.3075-3083, 2005.
DOI : 10.1158/1078-0432.CCR-04-1764

R. Banjerdpongchai, P. Kongtawelert, O. Khantamat, C. Srisomsap, and D. Chokchaichamnankit, Mitochondrial and endoplasmic reticulum stress pathways cooperate in zearalenone-induced apoptosis of human leukemic cells, Journal of Hematology & Oncology, vol.3, issue.1, pp.1-16, 2010.
DOI : 10.1186/1756-8722-3-50

S. Lacour, O. Micheau, A. Hammann, V. Drouineaud, and J. Tschopp, Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells, Oncogene, vol.22, issue.12, pp.1807-1816, 2003.
DOI : 10.1038/sj.onc.1206127