Fat accretion in a subpopulation of hepatocytes as a strategy to protect the whole liver against oxidative stress and lipotoxicity.

Bernard Fromenty 1, *
* Auteur correspondant
1 Hépatotoxicité et xénobiotiques
Foie, métabolismes et cancer
Abstract : : Fatty liver can be induced by obesity, some drugs and alcohol intoxication. In this liver lesion, lipid accumulation can involve only some hepatocytes but the significance of this cell-to-cell heterogeneity is unknown. In a recent work, Dr Pol et al. propose that high-fat hepatocytes could protect the cell population against oxidative stress and lipotoxicity.
Type de document :
Article dans une revue
Gastroentérologie Clinique et Biologique / Research and Clinics in Hepatology and Gastroenterology, Elsevier Masson, 2013, 37 (6), pp.553-555. 〈10.1016/j.clinre.2013.08.005〉
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http://www.hal.inserm.fr/inserm-00869996
Contributeur : Nathalie Coval <>
Soumis le : vendredi 4 octobre 2013 - 16:02:31
Dernière modification le : mercredi 16 mai 2018 - 11:24:08

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Bernard Fromenty. Fat accretion in a subpopulation of hepatocytes as a strategy to protect the whole liver against oxidative stress and lipotoxicity.. Gastroentérologie Clinique et Biologique / Research and Clinics in Hepatology and Gastroenterology, Elsevier Masson, 2013, 37 (6), pp.553-555. 〈10.1016/j.clinre.2013.08.005〉. 〈inserm-00869996〉

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