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Fat accretion in a subpopulation of hepatocytes as a strategy to protect the whole liver against oxidative stress and lipotoxicity.

Bernard Fromenty 1, *
* Corresponding author
Abstract : : Fatty liver can be induced by obesity, some drugs and alcohol intoxication. In this liver lesion, lipid accumulation can involve only some hepatocytes but the significance of this cell-to-cell heterogeneity is unknown. In a recent work, Dr Pol et al. propose that high-fat hepatocytes could protect the cell population against oxidative stress and lipotoxicity.
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https://www.hal.inserm.fr/inserm-00869996
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Submitted on : Friday, October 4, 2013 - 4:02:31 PM
Last modification on : Friday, February 14, 2020 - 1:50:04 PM

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Bernard Fromenty. Fat accretion in a subpopulation of hepatocytes as a strategy to protect the whole liver against oxidative stress and lipotoxicity.. Gastroentérologie Clinique et Biologique / Research and Clinics in Hepatology and Gastroenterology, Elsevier Masson, 2013, 37 (6), pp.553-555. ⟨10.1016/j.clinre.2013.08.005⟩. ⟨inserm-00869996⟩

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