J. Vincent, D. Backer, and D. , Microvascular dysfunction as a cause of organ dysfunction in severe sepsis, Critical Care, vol.9, issue.Suppl 4, pp.9-12, 2005.
DOI : 10.1186/cc3748

C. Ince, The microcirculation is the motor of sepsis, Critical Care, vol.9, issue.Suppl 4, pp.13-19, 2005.
DOI : 10.1186/cc3753

D. Backer, D. Creteur, J. Preiser, J. Dubois, M. Vincent et al., Microvascular Blood Flow Is Altered in Patients with Sepsis, American Journal of Respiratory and Critical Care Medicine, vol.166, issue.1, pp.98-104, 2002.
DOI : 10.1164/rccm.200109-016OC

J. Creteur, T. Carollo, G. Soldati, G. Buchele, D. Backer et al., The prognostic value of muscle StO2 in septic patients, Intensive Care Medicine, vol.101, issue.9, pp.1549-1556, 2007.
DOI : 10.1007/s00134-007-0739-3

H. Ait-oufella, S. Lemoinne, P. Boelle, A. Galbois, J. Baudel et al., Mottling score predicts survival in septic shock, Intensive Care Medicine, vol.34, issue.6, pp.801-807, 2011.
DOI : 10.1007/s00134-011-2163-y

R. Dellinger, M. Levy, J. Carlet, J. Bion, M. Parker et al., Surviving Sepsis Campaign, Critical Care Medicine, vol.41, issue.2, pp.296-327, 2008.
DOI : 10.1097/CCM.0b013e31827e83af

R. Moreno, J. Vincent, R. Matos, A. Mendonca, F. Cantraine et al., The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study, Intensive Care Medicine, vol.25, issue.7, pp.686-696, 1999.
DOI : 10.1007/s001340050931

L. Gall, J. Lemeshow, S. Saulnier, and F. , A New Simplified Acute Physiology Score (SAPS II) Based on a European/North American Multicenter Study, JAMA: The Journal of the American Medical Association, vol.270, issue.24, pp.2957-2963, 1993.
DOI : 10.1001/jama.1993.03510240069035

O. Saez, A. Mosel, F. Nurnberger, J. Rushentsova, U. Gossl et al., Laser Doppler imager (LDI) scanner and intradermal injection for in vivo pharmacology in human skin microcirculation: responses to acetylcholine, endothelin-1 and their repeatability, British Journal of Clinical Pharmacology, vol.2, issue.2, pp.511-519, 2005.
DOI : 10.1109/10.222322

K. Terada, N. Miyai, Y. Maejima, S. Sakaguchi, T. Tomura et al., Laser Doppler Imaging of Skin Blood Flow for Assessing Peripheral Vascular Impairment in Hand-Arm Vibration Syndrome, Industrial Health, vol.45, issue.2, pp.309-317, 2007.
DOI : 10.2486/indhealth.45.309

E. Boerma, The microcirculation as a clinical concept: work in progress, Current Opinion in Critical Care, vol.15, issue.3, pp.261-265, 2009.
DOI : 10.1097/MCC.0b013e32832b0ff4

W. Altemeier and C. W. , Septic Shock, Annals of Surgery, vol.143, issue.5, pp.600-607, 1956.
DOI : 10.1097/00000658-195605000-00006

F. Vachon, E. J. Bazin, and C. , Conception actuelle du traitement du choc infectieux. Paris: Editions Arnette, 1968.

H. Ait-oufella, J. Joffre, P. Boelle, A. Galbois, S. Bourcier et al., Knee area tissue oxygen saturation is predictive of 14-day mortality in septic shock, Intensive Care Medicine, vol.39, issue.Suppl 5, pp.976-983, 2012.
DOI : 10.1007/s00134-012-2555-7

A. Lima, M. Van-genderen, E. Klijn, J. Bakker, and J. Van-bommel, Peripheral vasoconstriction influences thenar oxygen saturation as measured by near-infrared spectroscopy, Intensive Care Medicine, vol.37, issue.4, pp.606-611, 2012.
DOI : 10.1007/s00134-012-2486-3

W. Aird, Endothelial cell heterogeneity, Critical Care Medicine, vol.31, issue.Supplement, pp.221-230, 2003.
DOI : 10.1097/01.CCM.0000057847.32590.C1

H. Ait-oufella, E. Maury, S. Lehoux, B. Guidet, and G. Offenstadt, The endothelium: physiological functions and role in microcirculatory failure during severe sepsis, Intensive Care Medicine, vol.99, issue.Suppl 7, pp.1286-1298, 2010.
DOI : 10.1007/s00134-010-1893-6