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Journal articles
Neuroprotective role of PKR in a model of neurodegeneration due to mild impairment of oxidative metabolism
Abstract : Abnormalities in oxidativemetabolism, inflammation,and selective neuronal death are described features of Alzheimer 's disease (AD) pathology. Brain thiamine-dependent enzymes play an important role in energy metabolism and display reduced activity in AD. Thiamine (vitamin B1) deficiency (TD) induces regionally selective neuronal death in animal and human brains.
https://www.hal.inserm.fr/inserm-00868757
Contributor : Ed. BMC Connect in order to contact the contributor
Submitted on : Tuesday, October 1, 2013 - 9:49:59 PM
Last modification on : Sunday, June 26, 2022 - 9:45:43 AM
Long-term archiving on: : Thursday, January 2, 2014 - 11:30:14 AM
Contributor : Ed. BMC Connect in order to contact the contributor
Submitted on : Tuesday, October 1, 2013 - 9:49:59 PM
Last modification on : Sunday, June 26, 2022 - 9:45:43 AM
Long-term archiving on: : Thursday, January 2, 2014 - 11:30:14 AM