O. O. Adesanya-famuyiwa, J. Zhou, G. Wu, and C. Bondy, Localization and sex steroid regulation of androgen receptor gene expression in rhesus monkey uterus, Obstet. Gynecol, vol.93, pp.265-270, 1999.

E. M. Andresen, J. A. Malmgren, W. B. Carter, and D. L. Patrick, Screening for depression in well older adults: evaluation of a short form of the CES-D, Am. J. Prev. Med, vol.10, pp.77-84, 1994.

A. P. Arnold, The organizational???activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues, Hormones and Behavior, vol.55, issue.5, pp.570-578, 2009.
DOI : 10.1016/j.yhbeh.2009.03.011

E. Barrett-connor and D. Goodman-gruen, Cognitive Function and Endogenous Sex Hormones in Older Women, Journal of the American Geriatrics Society, vol.13, issue.11, pp.1289-1293, 1999.
DOI : 10.1111/j.1532-5415.1999.tb07427.x

A. L. Benton, N. R. Varney, and K. Hamsher, Visuospatial Judgment, Archives of Neurology, vol.35, issue.6, pp.364-367, 1978.
DOI : 10.1001/archneur.1978.00500300038006

W. C. Boon, J. D. Chow, and E. R. Simpson, The Multiple Roles of Estrogens and the Enzyme Aromatase, Prog. Brain Res, vol.181, pp.209-232, 2010.
DOI : 10.1016/S0079-6123(08)81012-6

H. G. Burger, E. C. Dudley, J. L. Hopper, J. M. Shelley, A. Green et al., The Menopausal Transition???Endocrinology, The Journal of Sexual Medicine, vol.5, issue.10, pp.3537-3545, 1995.
DOI : 10.1111/j.1743-6109.2008.00921.x

H. G. Burger, E. C. Dudley, J. Cui, L. Dennerstein, and J. L. Hopper, A Prospective Longitudinal Study of Serum Testosterone, Dehydroepiandrosterone Sulfate, and Sex Hormone-Binding Globulin Levels through the Menopause Transition, Journal of Clinical Endocrinology & Metabolism, vol.85, issue.8, pp.2832-2838, 2000.
DOI : 10.1210/jc.85.8.2832

H. G. Burger, G. E. Hale, D. M. Robertson, and L. Dennerstein, A review of hormonal changes during the menopausal transition: focus on findings from the Melbourne Women's Midlife Health Project, Human Reproduction Update, vol.13, issue.6, pp.559-565, 2007.
DOI : 10.1093/humupd/dmm020

L. E. Carlson and B. B. Sherwin, Higher Levels of Plasma Estradiol and Testosterone in Healthy Elderly Men Compared With Age-Matched Women May Protect Aspects of Explicit Memory, Menopause, vol.7, issue.3, pp.168-177, 2000.
DOI : 10.1097/00042192-200007030-00007

P. Chen, G. Ratcliff, S. H. Belle, J. A. Cauley, S. T. Dekosky et al., Cognitive tests that best discriminate between presymptomatic AD and those who remain nondemented, Neurology, vol.55, issue.12, pp.1847-1853, 2000.
DOI : 10.1212/WNL.55.12.1847

M. S. Clark, L. Dennerstein, S. Elkadi, J. R. Guthrie, S. C. Bowden et al., Normative verbal and non-verbal memory test scores for Australian women aged 56-67, Aust. N. Z. J. Psychiatry, vol.38, pp.532-540, 2004.

M. S. Clark, L. Dennerstein, S. Elkadi, J. R. Guthrie, S. C. Bowden et al., Normative data for tasks of executive function and working memory for Australian-born women aged 56-67, Australian Psychologist, vol.298, issue.2, pp.56-67, 2004.
DOI : 10.1080/00050060412331295126

A. Collie, R. Shafiq-antonacci, P. Maruff, P. Tyler, and J. Currie, Norms and the Effects of Demographic Variables on a Neuropsychological Battery for Use in Healthy Ageing Australian Populations, Australian & New Zealand Journal of Psychiatry, vol.46, issue.3, pp.568-575, 1999.
DOI : 10.1177/014662167700100306

S. Davison, R. Bell, S. Donath, J. Montalto, and S. R. Davis, Androgen Levels in Adult Females: Changes with Age, Menopause, and Oophorectomy, The Journal of Clinical Endocrinology & Metabolism, vol.90, issue.7, pp.3847-3853, 2005.
DOI : 10.1210/jc.2005-0212

D. C. Delis, J. Kramer, E. Kaplan, and B. A. Ober, CVLT-II. California Verbal Learning Test, second edition, adult version, 2000.

L. Dennerstein, A. M. Smith, C. A. Morse, A. Green, H. Burger et al., Menopausal symptoms in Australian women, Med. J. Aust, vol.159, pp.232-236, 1993.

E. B. Drake, V. W. Henderson, F. Z. Stanczyk, C. A. Mccleary, W. S. Brown et al., Associations between circulating sex steroid hormones and cognition in normal elderly women, Neurology, vol.54, issue.3, pp.599-603, 2000.
DOI : 10.1212/WNL.54.3.599

S. Elkadi, M. S. Clark, L. Dennerstein, J. R. Guthrie, S. C. Bowden et al., Normative visuospatial performance in Australian midlife women, Australian Psychologist, vol.63, issue.1, pp.43-47, 2006.
DOI : 10.1080/00050060500421642

S. Elkadi, M. S. Clark, L. Dennerstein, J. R. Guthrie, S. C. Bowden et al., Normative data for Australian midlife women on category fluencyand a short form of the Boston Naming Test, Australian Psychologist, vol.54, issue.2, pp.37-42, 2006.
DOI : 10.1080/00050060500421634

M. A. Espeland, S. R. Rapp, S. A. Shumaker, R. Brunner, J. E. Manson et al., Conjugated Equine Estrogens and Global Cognitive Function in Postmenopausal Women<SUBTITLE>Women's Health Initiative Memory Study</SUBTITLE>, JAMA, vol.291, issue.24, pp.2959-2968, 2004.
DOI : 10.1001/jama.291.24.2959

M. I. Geerlings, L. J. Launer, F. H. De-jong, A. Ruitenberg, T. Stijnen et al., Endogenous estradiol and risk of dementia in women and men: The Rotterdam Study, Annals of Neurology, vol.285, issue.5, pp.607-615, 2003.
DOI : 10.1002/ana.10521

U. Goebelsmann, J. J. Arce, I. H. Thorneycroft, D. R. Mishell, and . Jr, Serum testosterone concentrations in women throughout the menstrual cycle and following HCG administration, American Journal of Obstetrics and Gynecology, vol.119, issue.4, pp.445-452, 1974.
DOI : 10.1016/0002-9378(74)90199-9

U. Goebelsmann, G. S. Bernstein, J. A. Gale, O. A. Kletzky, R. M. Nakamura et al., Serum gonadotropin, testosterone, estradiol and estrone levels prior to and following bilateral vasectomy, Vasectomy: Immunologic and Pathophysiologic Effects in Animals and Man, pp.165-175, 1979.

M. González, A. Cabrera-socorro, C. G. Pérez-garcía, J. D. Fraser, F. J. López et al., Distribution patterns of estrogen receptor ?? and ?? in the human cortex and hippocampus during development and adulthood, The Journal of Comparative Neurology, vol.129, issue.6, pp.790-802, 2007.
DOI : 10.1002/cne.21419

V. W. Henderson, E. C. Dudley, J. R. Guthrie, H. G. Burger, and L. Dennerstein, Estrogen exposures and memory at midlife: A population-based study of women, Neurology, vol.60, issue.8, pp.1369-1371, 2003.
DOI : 10.1212/01.WNL.0000059413.75888.BE

V. W. Henderson and B. B. Sherwin, Surgical versus natural menopause, Menopause, vol.14, issue.Suppl. 1, pp.572-579, 2007.
DOI : 10.1097/gme.0b013e31803df49c

A. Herlitz, P. Thilers, and R. Habib, Endogenous estrogen is not associated with cognitive performance before, during, or after menopause, Menopause, vol.14, issue.3, pp.425-431, 2007.
DOI : 10.1097/01.gme.0000247019.86748.e3

J. E. Hixson and D. T. Vernier, Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI, J. Lipid Res, vol.31, pp.545-548, 1990.

E. Hogervorst, C. De-jager, M. Budge, and A. D. Smith, Serum levels of estradiol and testosterone and performance in different cognitive domains in healthy elderly men and women, Psychoneuroendocrinology, vol.29, issue.3, pp.405-421, 2004.
DOI : 10.1016/S0306-4530(03)00053-2

E. Hogervorst, F. E. Matthews, and C. Brayne, Are optimal levels of testosterone associated with better cognitive function in healthy older women and men?, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1800, issue.10, 2010.
DOI : 10.1016/j.bbagen.2009.12.009

E. K. Hoskin, M. X. Tang, J. J. Manly, and R. Mayeux, Elevated sex-hormone binding globulin in elderly women with Alzheimer???s disease, Neurobiology of Aging, vol.25, issue.2, pp.141-147, 2004.
DOI : 10.1016/S0197-4580(03)00046-0

H. Joffe, J. E. Hall, S. Gruber, I. A. Sarmiento, L. S. Cohen et al., Estrogen therapy selectively enhances prefrontal cognitive processes, Menopause, vol.13, issue.3, pp.411-422, 2006.
DOI : 10.1097/01.gme.0000189618.48774.7b

C. E. Lebrun, Y. T. Van-der-schouw, H. , D. J. Pols, H. A. Grobbee et al., Endogenous oestrogens are related to cognition in healthy elderly women, Clinical Endocrinology, vol.57, issue.1, pp.50-55, 2005.
DOI : 10.1210/jc.82.8.2403

A. Lethaby, E. Hogervorst, M. Richards, A. Yesufu, and K. Yaffe, Hormone replacement therapy for cognitive function in postmenopausal women, Cochrane Database Syst. Rev. Issue, vol.356, issue.2, 2008.
DOI : 10.1002/14651858.CD003122.pub2

C. Luetters, M. H. Huang, T. Seeman, G. Buckwalter, P. M. Meyer et al., Menopause Transition Stage and Endogenous Estradiol and Follicle-Stimulating Hormone Levels are Not Related to Cognitive Performance: Cross-Sectional Results from the Study of Women's Health across the Nation (SWAN), Journal of Women's Health, vol.16, issue.3, pp.331-344, 2007.
DOI : 10.1089/jwh.2006.0057

W. J. Mack, D. M. Freed, B. W. Williams, and V. W. Henderson, Boston Naming Test: Shortened Versions for Use in Alzheimer's Disease, Journal of Gerontology, vol.47, issue.3, pp.154-158, 1992.
DOI : 10.1093/geronj/47.3.P154

P. M. Maki, M. J. Gast, A. Vieweg, S. W. Burriss, and K. Yaffe, Hormone therapy in menopausal women with cognitive complaints: A randomized, double-blind trial, Neurology, vol.69, issue.13, pp.1322-1330, 2007.
DOI : 10.1212/01.wnl.0000277275.42504.93

J. J. Manly, C. A. Merchant, D. M. Jacobs, S. A. Small, K. Bell et al., Endogenous estrogen levels and Alzheimer's disease among postmenopausal women, Neurology, vol.54, issue.4, pp.833-837, 2000.
DOI : 10.1212/WNL.54.4.833

M. C. Möller, A. B. Bartfai, and A. F. Rådestad, Effects of testosterone and estrogen replacement on memory function, Menopause, vol.17, issue.5, 2010.
DOI : 10.1097/gme.0b013e3181dc2e40

H. Mukai, T. Tsurugizawa, M. Ogiue-ikeda, G. Murakami, Y. Hojo et al., Local Neurosteroid Production in the Hippocampus: Influence on Synaptic Plasticity of Memory, Neuroendocrinology, vol.84, issue.4, pp.255-263, 2006.
DOI : 10.1159/000097747

Y. Netz, S. Zach, J. R. Taffe, J. Guthrie, and L. Dennerstein, Habitual physical activity is a meaningful predictor of well-being in mid-life women: a longitudinal analysis, Climacteric, vol.125, issue.4, pp.337-344, 2008.
DOI : 10.1037/0003-066X.47.9.1102

V. Panet-raymond, B. Gottlieb, L. K. Beitel, L. Pinsky, and M. A. Trifiro, Interactions between androgen and estrogen receptors and the effects on their transactivational properties, Molecular and Cellular Endocrinology, vol.167, issue.1-2, pp.139-150, 2000.
DOI : 10.1016/S0303-7207(00)00279-3

K. Patterson, P. Nestor, and T. T. Rogers, Where do you know what you know? The representation of semantic knowledge in the human brain, Nature Reviews Neuroscience, vol.9, issue.12, pp.976-987, 2007.
DOI : 10.1038/nrn2277

C. J. Pike, J. C. Carroll, E. R. Rosario, and A. M. Barron, Protective actions of sex steroid hormones in Alzheimer???s disease, Frontiers in Neuroendocrinology, vol.30, issue.2, pp.239-258, 2009.
DOI : 10.1016/j.yfrne.2009.04.015

L. S. Radloff, The CES-D Scale: A Self-Report Depression Scale for Research in the General Population, Applied Psychological Measurement, vol.1, issue.3, pp.385-401, 1977.
DOI : 10.1177/014662167700100306

R. M. Reitan, VALIDITY OF THE TRAIL MAKING TEST AS AN INDICATOR OF ORGANIC BRAIN DAMAGE, Perceptual and Motor Skills, vol.19, issue.3, pp.271-276, 1958.
DOI : 10.2466/pms.1958.8.3.271

S. Rinaldi, A. Geay, H. Déchaud, C. Biessy, A. Zeleniuch-jacquotte et al., Validity of free testosterone and free estradiol determinations in serum samples from postmenopausal women by theoretical calculations, Cancer Epidemiol. Biomarkers Prev, vol.11, pp.1065-1071, 2002.

J. Ryan, H. G. Burger, C. Szoeke, P. Lehert, M. L. Ancelin et al., A prospective study of the association between endogenous hormones and depressive symptoms in postmenopausal women, Menopause, vol.16, issue.3, pp.509-517, 2009.
DOI : 10.1097/gme.0b013e31818d635f

URL : https://hal.archives-ouvertes.fr/inserm-00360648

P. K. Sharma and M. K. Thakur, Expression of estrogen receptor (ER) ?? and ?? in mouse cerebral cortex: Effect of age, sex and gonadal steroids, Neurobiology of Aging, vol.27, issue.6, pp.880-887, 2006.
DOI : 10.1016/j.neurobiolaging.2005.04.003

R. B. Simerly, C. Chang, M. Muramatsu, and L. W. Swanson, Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study, The Journal of Comparative Neurology, vol.19, issue.1, pp.76-95, 1990.
DOI : 10.1002/cne.902940107

B. J. Small, L. Fratiglioni, M. Viitanen, B. Winblad, and L. Bäckman, The Course of Cognitive Impairment in Preclinical Alzheimer Disease, Archives of Neurology, vol.57, issue.6, pp.839-844, 2000.
DOI : 10.1001/archneur.57.6.839

A. Smith, Symbol Digit Modalities Test Manual. Western Psychological Services, 1991.
DOI : 10.1037/t27513-000

R. Södergård, T. Bäckström, V. Shanbhag, and H. Carstensen, Calculation of free and bound fractions of testosterone and estradiol-17?? to human plasma proteins at body temperature, Journal of Steroid Biochemistry, vol.16, issue.6, pp.801-810, 1982.
DOI : 10.1016/0022-4731(82)90038-3

J. L. Spencer, E. M. Waters, R. D. Romeo, G. E. Wood, T. A. Milner et al., Uncovering the mechanisms of estrogen effects on hippocampal function, Frontiers in Neuroendocrinology, vol.29, issue.2, pp.219-237, 2008.
DOI : 10.1016/j.yfrne.2007.08.006

J. Taffe and L. Dennerstein, Retrospective self-report compared with menstrual diary data prospectively kept during the menopausal transition, Climacteric, vol.8, issue.1, pp.183-191, 2000.
DOI : 10.1137/1.9781611970319

P. P. Thilers, S. W. Macdonald, and A. Herlitz, The association between endogenous free testosterone and cognitive performance: A population-based study in 35 to 90 year-oldmen and women, Psychoneuroendocrinology, vol.31, issue.5, pp.565-576, 2006.
DOI : 10.1016/j.psyneuen.2005.12.005

A. K. Troyer, Normative Data for Clustering and Switching on Verbal Fluency Tasks, Journal of Clinical and Experimental Neuropsychology, vol.22, issue.3, pp.370-378, 2000.
DOI : 10.1076/1380-3395(200006)22:3;1-V;FT370

A. Vermeulen, L. Verdonck, and J. M. Kaufman, A Critical Evaluation of Simple Methods for the Estimation of Free Testosterone in Serum, The Journal of Clinical Endocrinology & Metabolism, vol.84, issue.10, pp.3666-3672, 1999.
DOI : 10.1210/jcem.84.10.6079

D. Wechsler, Wechsler Adult Intelligence Scale -III. Psychological Corporation, 1991.

D. Wechsler, WMS-III. Wechsler Memory Scale -third edition. Psychological Corporation, 1997.

S. Weintraub, D. Salmon, N. Mercaldo, S. Ferris, N. R. Graff-radford et al., The Alzheimer??s Disease Centers?? Uniform Data Set (UDS), Alzheimer Disease & Associated Disorders, vol.23, issue.2, pp.91-101, 2009.
DOI : 10.1097/WAD.0b013e318191c7dd

O. T. Wolf and C. Kirschbaum, Endogenous Estradiol and Testosterone Levels Are Associated with Cognitive Performance in Older Women and Men, Hormones and Behavior, vol.41, issue.3, pp.259-266, 2002.
DOI : 10.1006/hbeh.2002.1770

N. F. Woods, E. S. Mitchell, and C. Adams, Memory Functioning Among Midlife Women, Menopause, vol.7, issue.4, pp.257-265, 2000.
DOI : 10.1097/00042192-200007040-00008

K. Yaffe, L. Y. Lui, D. Grady, J. Cauley, J. Kramer et al., Cognitive decline in women in relation to non-protein-bound oestradiol concentrations, The Lancet, vol.356, issue.9231, pp.708-712, 2000.
DOI : 10.1016/S0140-6736(00)02628-3