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Journal Articles Journal of Therapeutic Ultrasound Year : 2013

The road to clinical use of high-intensity focused ultrasound for liver cancer: technical and clinical consensus

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Kim Butts Pauly
  • Function : Author
  • PersonId : 944510
Chrit Moonen
  • Function : Author
  • PersonId : 944511
Gail Ter Haar
  • Function : Author
  • PersonId : 939546
Mario Ries
  • Function : Author
  • PersonId : 944512
Rares Salomir
  • Function : Author
  • PersonId : 944513
Sham Sokka
  • Function : Author
  • PersonId : 944514
Kevin Michael Sekins
  • Function : Author
  • PersonId : 944515
Yerucham Shapira
  • Function : Author
  • PersonId : 944516
Fangwei Ye
  • Function : Author
  • PersonId : 944517
Heather Huff-Simonin
  • Function : Author
  • PersonId : 944518
Matt Eames
  • Function : Author
  • PersonId : 944519
Neal Kassell
  • Function : Author
  • PersonId : 944521
Joo Ha Hwang
  • Function : Author
  • PersonId : 944523
Feng Wu
  • Function : Author
  • PersonId : 944524
Lian Zhang
  • Function : Author
  • PersonId : 944525
Andreas Melzer
  • Function : Author
  • PersonId : 944526
Young-Sun Kim
  • Function : Author
  • PersonId : 944527

Abstract

Clinical use of high-intensity focused ultrasound (HIFU) under ultrasound or MR guidance as a non-invasive method for treating tumors is rapidly increasing. Tens of thousands of patients have been treated for uterine fibroid, benign prostate hyperplasia, bone metastases, or prostate cancer. Despite the methods' clinical potential, the liver is a particularly challenging organ for HIFU treatment due to the combined effect of respiratory-induced liver motion, partial blocking by the rib cage, and high perfusion/flow. Several technical and clinical solutions have been developed by various groups during the past 15 years to compensate for these problems. A review of current unmet clinical needs is given here, as well as a consensus from a panel of experts about technical and clinical requirements for upcoming pilot and pivotal studies in order to accelerate the development and adoption of focused ultrasound for the treatment of primary and secondary liver cancer.
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Dates and versions

inserm-00851863 , version 1 (19-08-2013)

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  • HAL Id : inserm-00851863 , version 1

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Jean-Francois Aubry, Kim Butts Pauly, Chrit Moonen, Gail Ter Haar, Mario Ries, et al.. The road to clinical use of high-intensity focused ultrasound for liver cancer: technical and clinical consensus. Journal of Therapeutic Ultrasound, 2013, 1 (1), pp.13. ⟨inserm-00851863⟩
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