S. Sahn, Malignant pleural effusions, Pleural disease, pp.411-438

A. Scherpereel, Guidelines of the European Respiratory Society and the European Society of Thoracic Surgeons for the management of malignant pleural mesothelioma, European Respiratory Journal, vol.35, issue.3, pp.479-495, 2010.
DOI : 10.1183/09031936.00063109

B. Robinson, C. Robinson, and R. Lake, Localised spontaneous regression in mesothelioma ??? possible immunological mechanism, Lung Cancer, vol.32, issue.2, pp.197-201, 2001.
DOI : 10.1016/S0169-5002(00)00217-8

P. Astoul, Intrapleural administration of interleukin-2 for the treatment of patients with malignant pleural mesothelioma, Cancer, vol.6, issue.10, pp.2099-2104, 1998.
DOI : 10.1002/(SICI)1097-0142(19981115)83:10<2099::AID-CNCR8>3.0.CO;2-3

C. Boutin, Intrapleural treatment with recombinant gamma-interferon in early stage malignant pleural mesothelioma, Cancer, vol.15, issue.9, pp.2460-2467, 1994.
DOI : 10.1002/1097-0142(19941101)74:9<2460::AID-CNCR2820740912>3.0.CO;2-N

M. Sebastian, Treatment of Malignant Pleural Effusion With the Trifunctional Antibody Catumaxomab (Removab) (Anti-EpCAM??Anti-CD3), Journal of Immunotherapy, vol.32, issue.2, pp.195-202, 2009.
DOI : 10.1097/CJI.0b013e318195b5bb

J. Hegmans, Immunotherapy of Murine Malignant Mesothelioma Using Tumor Lysate???pulsed Dendritic Cells, American Journal of Respiratory and Critical Care Medicine, vol.171, issue.10, pp.1711168-1177, 2005.
DOI : 10.1164/rccm.200501-057OC

J. Hegmans, Consolidative Dendritic Cell-based Immunotherapy Elicits Cytotoxicity against Malignant Mesothelioma, American Journal of Respiratory and Critical Care Medicine, vol.181, issue.12, pp.1383-1390, 2010.
DOI : 10.1164/rccm.200909-1465OC

D. Sterman, A Trial of Intrapleural Adenoviral-mediated Interferon-??2b Gene Transfer for Malignant Pleural Mesothelioma, American Journal of Respiratory and Critical Care Medicine, vol.184, issue.12, pp.1395-1399, 2011.
DOI : 10.1164/rccm.201103-0554CR

M. Gregoire, Dendritic cell vaccination as a treatment modality for mesothelioma, Expert Review of Respiratory Medicine, vol.4, issue.3, pp.311-314
DOI : 10.1586/ers.10.33

V. Antony, Recruitment of inflammatory cells to the pleural space Chemotactic cytokines, IL-8, and monocyte chemotactic peptide-1 in human pleural fluids, J Immunol, vol.151, issue.12, pp.7216-7223, 1993.

F. Sallusto and A. Lanzavecchia, Heterogeneity of CD4+ memory T cells: Functional modules for tailored immunity, European Journal of Immunology, vol.30, issue.8, pp.2076-2082, 2009.
DOI : 10.1002/eji.200939722

F. Sallusto, Two subsets of memory T lymphocytes with distinct homing potentials and effector functions, Nature, vol.9, issue.6754, pp.708-712, 1999.
DOI : 10.1038/44385

E. Wherry, Lineage relationship and protective immunity of memory CD8 T cell subsets, Nature Immunology, vol.4, issue.3, pp.225-234, 2003.
DOI : 10.1038/ni889

A. Harari, Functional Heterogeneity of Memory CD4 T Cell Responses in Different Conditions of Antigen Exposure and Persistence, The Journal of Immunology, vol.174, issue.2, pp.1037-1045, 2005.
DOI : 10.4049/jimmunol.174.2.1037

A. Roberts and D. Woodland, Cutting Edge: Effector Memory CD8+ T Cells Play a Prominent Role in Recall Responses to Secondary Viral Infection in the Lung, The Journal of Immunology, vol.172, issue.11, pp.6533-6537, 2004.
DOI : 10.4049/jimmunol.172.11.6533

C. Klebanoff, L. Gattinoni, and N. Restifo, CD8+ T-cell memory in tumor immunology and immunotherapy, Immunological Reviews, vol.61, issue.1, pp.214-224, 2006.
DOI : 10.1016/j.coi.2005.02.002

M. Okamoto, T-Helper Type 1/T-Helper Type 2 Balance in Malignant Pleural Effusions Compared to Tuberculous Pleural Effusions, Chest, vol.128, issue.6, pp.4030-4035, 2005.
DOI : 10.1378/chest.128.6.4030

L. Aguiar, Malignant and tuberculous pleural effusions: immunophenotypic cellular characterization, Clinics, vol.63, issue.5, pp.637-644, 2008.
DOI : 10.1590/S1807-59322008000500012

J. Klimiuk, Lymphocyte and lymphocyte subsets in pleural fluid--comparison of malignant and non-malignant disorders, Pol Arch Med Wewn, vol.111, issue.3, pp.291-296, 2004.

A. Scherpereel, Soluble Mesothelin???related Peptides in the Diagnosis of Malignant Pleural Mesothelioma, American Journal of Respiratory and Critical Care Medicine, vol.173, issue.10, pp.1155-1160, 2006.
DOI : 10.1164/rccm.200511-1789OC

B. Grigoriu, Utility of Osteopontin and Serum Mesothelin in Malignant Pleural Mesothelioma Diagnosis and Prognosis Assessment, Clinical Cancer Research, vol.13, issue.10, pp.2928-2935, 2007.
DOI : 10.1158/1078-0432.CCR-06-2144

M. Noppen, Volume and Cellular Content of Normal Pleural Fluid in Humans Examined by Pleural Lavage, American Journal of Respiratory and Critical Care Medicine, vol.162, issue.3, pp.1023-1026, 2000.
DOI : 10.1164/ajrccm.162.3.9910050

W. Conover and R. Iman, Analysis of Covariance Using the Rank Transformation, Biometrics, vol.38, issue.3, pp.715-724, 1982.
DOI : 10.2307/2530051

C. Baecher-allan, CD4+CD25high Regulatory Cells in Human Peripheral Blood, The Journal of Immunology, vol.167, issue.3, pp.1245-1253, 2001.
DOI : 10.4049/jimmunol.167.3.1245

P. Saule, Accumulation of memory T cells from childhood to old age: Central and effector memory cells in CD4+ versus effector memory and terminally differentiated memory cells in CD8+ compartment, Mechanisms of Ageing and Development, vol.127, issue.3, pp.274-281, 2006.
DOI : 10.1016/j.mad.2005.11.001

D. Atanackovic, Characterization of Effusion-Infiltrating T Cells: Benign versus Malignant Effusions, Clinical Cancer Research, vol.10, issue.8, pp.2600-2608, 2004.
DOI : 10.1158/1078-0432.CCR-03-0239

H. Prado-garcia, Effector, memory and na??ve CD8+ T cells in peripheral blood and pleural effusion from lung adenocarcinoma patients, Lung Cancer, vol.47, issue.3, pp.361-371, 2005.
DOI : 10.1016/j.lungcan.2004.07.046

R. Khalil and M. Khalil, Letter: Flow cytometric study of T-cell subsets in lymphocytic pleural effusions, Cytometry, vol.30, issue.4, pp.204-205, 1997.
DOI : 10.1002/(SICI)1097-0320(19970815)30:4<204::AID-CYTO8>3.0.CO;2-J

K. Szyllo, The involvement of T lymphocytes in the pathogenesis of endometriotic tissues overgrowth in women with endometriosis, Mediators of Inflammation, vol.12, issue.3, pp.131-138, 2003.
DOI : 10.1080/0962935031000134842

G. Lucivero, G. Pierucci, and L. Bonomo, Lymphocyte subsets in peripheral blood and pleural fluid, Eur Respir J, vol.1, issue.4, pp.337-340, 1988.

S. Jose and M. , Lymphocyte Populations in Tuberculous Pleural Effusions, Annals of Clinical Biochemistry: An international journal of biochemistry and laboratory medicine, vol.36, issue.4, pp.492-500, 1999.
DOI : 10.1177/000456329903600413

A. Jassar, Activation of Tumor-Associated Macrophages by the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid Induces an Effective CD8+ T-Cell-Mediated Antitumor Immune Response in Murine Models of Lung Cancer and Mesothelioma, Cancer Research, vol.65, issue.24, pp.6511752-11761, 2005.
DOI : 10.1158/0008-5472.CAN-05-1658

M. Odaka, Eradication of intraperitoneal and distant tumor by adenovirus-mediated interferon-beta gene therapy is attributable to induction of systemic immunity, Cancer Res, issue.16, pp.616201-6212, 2001.

L. Zhang, Intratumoral T Cells, Recurrence, and Survival in Epithelial Ovarian Cancer, New England Journal of Medicine, vol.348, issue.3, pp.203-213, 2003.
DOI : 10.1056/NEJMoa020177

V. Shankaran, IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity, Nature, vol.410, issue.6832, pp.1107-1111, 2001.
DOI : 10.1038/35074122

F. Balkwill, Chemokine biology in cancer, Seminars in Immunology, vol.15, issue.1, pp.49-55, 2003.
DOI : 10.1016/S1044-5323(02)00127-6

D. Atanackovic, The Local Cytokine and Chemokine Milieu within Malignant Effusions, Tumor Biology, vol.29, issue.2, pp.93-104, 2008.
DOI : 10.1159/000135689

T. Hoffmann, Spontaneous apoptosis of circulating T lymphocytes in patients with head and neck cancer and its clinical importance, Clin Cancer Res, vol.8, issue.8, pp.2553-2562, 2002.

D. Lockhart, Loss of T-cell receptor-CD3?? and T-cell function in tumor-infiltrating lymphocytes but not in tumor-associated lymphocytes in ovarian carcinoma, Surgery, vol.129, issue.6, pp.749-756, 2001.
DOI : 10.1067/msy.2001.114554

M. Oka, The characterization of peritoneal and pleural exudate cells from malignant effusions, Surgery Today, vol.46, issue.6, pp.500-503, 1993.
DOI : 10.1007/BF00730624

J. Sikora and J. Zeromski, Expression of TCR-zeta chain and apoptosis in subpopulations of tumor-associated lymphocytes (TALs) from malignant pleural effusions, Folia Histochem Cytobiol, vol.40, issue.4, pp.347-351, 2002.

T. Whiteside, Signaling defects in T lymphocytes of patients with malignancy, Cancer Immunology, Immunotherapy, vol.48, issue.7, pp.346-352, 1999.
DOI : 10.1007/s002620050585

Y. Chen, Regulatory T Lymphocytes in Malignant Pleural Effusion, American Journal of Respiratory and Critical Care Medicine, vol.172, issue.11, pp.1434-1439, 2005.
DOI : 10.1164/rccm.200504-588OC

P. Delong, Regulatory T cells and cytokines in malignant pleural effusions secondary to mesothelioma and carcinoma, Cancer Biology & Therapy, vol.4, issue.3, pp.342-346, 2005.
DOI : 10.4161/cbt.4.3.1644

H. Li, Increased prevalence of regulatory T cells in the lung cancer microenvironment: a role of thymic stromal lymphopoietin, Cancer Immunology, Immunotherapy, vol.15, issue.7, pp.601587-1596, 2011.
DOI : 10.1007/s00262-011-1059-6

X. Qin, CCL22 Recruits CD4-positive CD25-positive Regulatory T Cells into Malignant Pleural Effusion, Clinical Cancer Research, vol.15, issue.7, pp.2231-2237, 2009.
DOI : 10.1158/1078-0432.CCR-08-2641

J. Hegmans, Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responses, European Respiratory Journal, vol.27, issue.6, pp.1086-1095, 2006.
DOI : 10.1183/09031936.06.00135305
URL : https://biblio.ugent.be/doc/api

G. Stathopoulos, A Central Role for Tumor-derived Monocyte Chemoattractant Protein-1 in Malignant Pleural Effusion, JNCI Journal of the National Cancer Institute, vol.100, issue.20, pp.1464-1476, 2008.
DOI : 10.1093/jnci/djn325

Y. Chen, Elevation of Interleukin-10 Levels in Malignant Pleural Effusion, Chest, vol.110, issue.2, pp.433-436, 1996.
DOI : 10.1378/chest.110.2.433

F. Colucci, D. Santo, J. Leibson, and P. , Natural killer cell activation in mice and men: different triggers for similar weapons?, Nature Immunology, vol.3, issue.9, pp.807-813, 2002.
DOI : 10.1038/ni0902-807

M. Loza, Expression of type 1 (interferon gamma) and type 2 (interleukin-13, interleukin-5) cytokines at distinct stages of natural killer cell differentiation from progenitor cells, Blood, vol.99, issue.4, pp.1273-1281, 2002.
DOI : 10.1182/blood.V99.4.1273

N. Yamada, CD8+ tumor-infiltrating lymphocytes predict favorable prognosis in malignant pleural mesothelioma after resection, Cancer Immunology, Immunotherapy, vol.15, issue.10, pp.1543-1549, 2010.
DOI : 10.1007/s00262-010-0881-6

M. Heuvers, J. Aerts, R. Cornelissen, H. Groen, H. Hoogsteden et al., Patient-tailored modulation of the immune system may revolutionize future lung cancer treatment, BMC Cancer, vol.11, issue.Suppl 1, p.580, 2012.
DOI : 10.1586/era.11.57

A. Thomas and R. Hassan, Immunotherapies for non-small-cell lung cancer and mesothelioma, The Lancet Oncology, vol.13, issue.7, pp.301-310, 2012.
DOI : 10.1016/S1470-2045(12)70126-2