Optimal individual inversion time in brain arterial spin labeling perfusion magnetic resonance imaging: correlation with carotid hemodynamics measured with cine phase-contrast magnetic resonance imaging - Inserm - Institut national de la santé et de la recherche médicale Accéder directement au contenu
Article Dans Une Revue Journal of Computer Assisted Tomography Année : 2013

Optimal individual inversion time in brain arterial spin labeling perfusion magnetic resonance imaging: correlation with carotid hemodynamics measured with cine phase-contrast magnetic resonance imaging

Résumé

OBJECTIVE: The quantification of cerebral blood flow using pulsed arterial spin labeling could be erroneous with a nonoptimal inversion time (TI). We suggest that the optimal individual TI is dependent on the hemodynamic values of the supra-aortic vessels. METHODS: Twenty-two healthy volunteers (mean age, 31.8 years) underwent 7 pulsed arterial spin labeling scans at 3 T with TI ranging from 1200 to 1800 milliseconds every 100 milliseconds. The quantitative hemodynamic values of carotids were computed using a cine phase-contrast sequence. Optimal TIs were determined using visual and quantitative criteria. A correlation was sought between each optimal individual TI criterion and the hemodynamic parameter values. RESULTS: The optimal group TI was 1700 milliseconds. The individual analysis showed a significant correlation between the optimal TI of white matter signal-to-noise ratio and stroke distance, and the optimal TI of contrast-to-noise ratio with mean velocity. CONCLUSIONS: A correlation was found between optimal individual TIs and carotid hemodynamic parameters.
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Dates et versions

inserm-00845274 , version 1 (16-07-2013)

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Jean-Christophe Ferré, Jan Petr, Christian Barillot, Hélène Raoult, Jean-Yves Gauvrit. Optimal individual inversion time in brain arterial spin labeling perfusion magnetic resonance imaging: correlation with carotid hemodynamics measured with cine phase-contrast magnetic resonance imaging. Journal of Computer Assisted Tomography, 2013, 37 (2), pp.247-51. ⟨10.1097/RCT.0b013e31827cd548⟩. ⟨inserm-00845274⟩
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