Optimal individual inversion time in brain arterial spin labeling perfusion magnetic resonance imaging: correlation with carotid hemodynamics measured with cine phase-contrast magnetic resonance imaging

Jean-Christophe Ferré 1, 2, 3 Jan Petr 1 Christian Barillot 1, 3 Hélène Raoult 1, 2 Jean-Yves Gauvrit 1, 2, 3
1 VisAGeS - Vision, Action et Gestion d'informations en Santé
INSERM - Institut National de la Santé et de la Recherche Médicale : U746, Inria Rennes – Bretagne Atlantique , IRISA-D5 - SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE
2 Service de radiologie et imagerie médicale [Rennes]
3 Plateforme Neurinfo
Abstract : OBJECTIVE: The quantification of cerebral blood flow using pulsed arterial spin labeling could be erroneous with a nonoptimal inversion time (TI). We suggest that the optimal individual TI is dependent on the hemodynamic values of the supra-aortic vessels. METHODS: Twenty-two healthy volunteers (mean age, 31.8 years) underwent 7 pulsed arterial spin labeling scans at 3 T with TI ranging from 1200 to 1800 milliseconds every 100 milliseconds. The quantitative hemodynamic values of carotids were computed using a cine phase-contrast sequence. Optimal TIs were determined using visual and quantitative criteria. A correlation was sought between each optimal individual TI criterion and the hemodynamic parameter values. RESULTS: The optimal group TI was 1700 milliseconds. The individual analysis showed a significant correlation between the optimal TI of white matter signal-to-noise ratio and stroke distance, and the optimal TI of contrast-to-noise ratio with mean velocity. CONCLUSIONS: A correlation was found between optimal individual TIs and carotid hemodynamic parameters.
keyword : brain magnetic resonance imaging perfusion imaging arterial spin labeling
Document type :
Journal articles
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https://www.hal.inserm.fr/inserm-00845274
Contributor : Jean-Yves Gauvrit <>
Submitted on : Tuesday, July 16, 2013 - 5:02:11 PM
Last modification on : Tuesday, March 5, 2019 - 1:45:46 AM

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UNIV-RENNES1 | INRIA | IRISA-D5 | INSTITUT-TELECOM | IRISA | UR1-UFR-ISTIC | UNIV-RENNES

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Jean-Christophe Ferré, Jan Petr, Christian Barillot, Hélène Raoult, Jean-Yves Gauvrit. Optimal individual inversion time in brain arterial spin labeling perfusion magnetic resonance imaging: correlation with carotid hemodynamics measured with cine phase-contrast magnetic resonance imaging. Journal of Computer Assisted Tomography, Lippincott, Williams & Wilkins, 2013, 37 (2), pp.247-51. ⟨10.1097/RCT.0b013e31827cd548⟩. ⟨inserm-00845274⟩

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