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Journal articles
Optimal individual inversion time in brain arterial spin labeling perfusion magnetic resonance imaging: correlation with carotid hemodynamics measured with cine phase-contrast magnetic resonance imaging
Abstract : OBJECTIVE: The quantification of cerebral blood flow using pulsed arterial spin labeling could be erroneous with a nonoptimal inversion time (TI). We suggest that the optimal individual TI is dependent on the hemodynamic values of the supra-aortic vessels. METHODS: Twenty-two healthy volunteers (mean age, 31.8 years) underwent 7 pulsed arterial spin labeling scans at 3 T with TI ranging from 1200 to 1800 milliseconds every 100 milliseconds. The quantitative hemodynamic values of carotids were computed using a cine phase-contrast sequence. Optimal TIs were determined using visual and quantitative criteria. A correlation was sought between each optimal individual TI criterion and the hemodynamic parameter values. RESULTS: The optimal group TI was 1700 milliseconds. The individual analysis showed a significant correlation between the optimal TI of white matter signal-to-noise ratio and stroke distance, and the optimal TI of contrast-to-noise ratio with mean velocity. CONCLUSIONS: A correlation was found between optimal individual TIs and carotid hemodynamic parameters.
https://www.hal.inserm.fr/inserm-00845274
Contributor : Jean-Yves Gauvrit <>
Submitted on : Tuesday, July 16, 2013 - 5:02:11 PM
Last modification on : Friday, January 15, 2021 - 3:34:10 AM
Contributor : Jean-Yves Gauvrit <>
Submitted on : Tuesday, July 16, 2013 - 5:02:11 PM
Last modification on : Friday, January 15, 2021 - 3:34:10 AM