Prognostic factors for outcomes after mechanical thrombectomy with solitaire stent

Hélène Raoult 1 François Eugène 1 Jean-Christophe Ferré 1 Jean-Christophe Gentric 2 Thomas Ronzière 3 Aymeric Stamm 4 Jean-Yves Gauvrit 1
1 Service de radiologie et imagerie médicale [Rennes]
2 Service de radiologie [Brest]
3 Service de Neurologie [Rennes]
4 VisAGeS - Vision, Action et Gestion d'informations en Santé
INSERM - Institut National de la Santé et de la Recherche Médicale : U746, Inria Rennes – Bretagne Atlantique , IRISA-D5 - SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE
Abstract : BACKGROUND AND PURPOSE: Endovascular mechanical thrombectomy is emerging as a promising therapeutic approach for acute ischemic stroke. This study was aimed at identifying factors influencing outcomes after thrombectomy with a Solitaire stent device. MATERIALS AND METHODS: Forty-five consecutive patients treated with thrombectomy using Solitaire FR were retrospectively included. Clinical, imaging and logistic variables were analyzed. A multivariate logistic regression analysis was used to identify variables influencing clinical outcome, based on discharge NIHSS score change and mRS at 3 months. RESULTS: Patient mean age and initial NIHSS score was 58 years (range 24-88) and 17 (range 6-32), respectively. An MRI was performed for 80% of patients, showing severe DWI lesion for 28% of patients and associated FLAIR hyperintensity for 58% of patients. Mean time from symptom onset to recanalization was 299min for the 32 ACO and 473min for the 13 PCO. Angiographic efficacy (TICI 2b-3) was achieved for 93% of patients and good clinical outcomes at discharge and at 3 months (mRS≤2) were achieved for 49% and 58% of patients, respectively. Independent prognostic factors for predicting good clinical outcomes at discharge were a short time to recanalization and FLAIR negativity. At 3 months, they were a short time to recanalization and patient age. DWI lesion severity was an associated prognostic factor. CONCLUSION: Two main prognostic factors for predicting a good clinical outcome after thrombectomy at 3 months were short time from symptom onset to recanalization and patient age.
Keywords : Stroke Prognostic factors Thrombectomy
Type de document :
Article dans une revue
Journal de Neuroradiologie / Journal of Neuroradiology, Elsevier Masson, 2013, pp.252-259. 〈10.1016/j.neurad.2013.04.001〉
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http://www.hal.inserm.fr/inserm-00845262
Contributeur : Jean-Yves Gauvrit <>
Soumis le : mardi 16 juillet 2013 - 16:58:34
Dernière modification le : mercredi 16 mai 2018 - 11:24:04

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INRIA | UNIV-BREST | IRISA-D5 | IRISA | UR1-UFR-ISTIC | UNIV-RENNES

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Hélène Raoult, François Eugène, Jean-Christophe Ferré, Jean-Christophe Gentric, Thomas Ronzière, et al.. Prognostic factors for outcomes after mechanical thrombectomy with solitaire stent. Journal de Neuroradiologie / Journal of Neuroradiology, Elsevier Masson, 2013, pp.252-259. 〈10.1016/j.neurad.2013.04.001〉. 〈inserm-00845262〉

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