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Article Dans Une Revue Molecular Nutrition and Food Research Année : 2013

Lipidomics of essential fatty acids and oxygenated metabolites.

Résumé

Polyunsaturated fatty acids in mammals may be oxygenated into a myriad of bioactive products through di- and monooxygenases, products that are rapidly degraded to control their action. To evaluate the phenotypes of biological systems regarding this wide family of compounds, a lipidomics approach in function of time and compartments would be relevant. The current review takes into consideration most of the diverse oxygenated metabolites of essential fatty acids at large and their immediate degradation products. Their biological function and life span are considered. Overall, this is a fluxolipidomics approach that is emerging.
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Dates et versions

inserm-00843903 , version 1 (12-07-2013)

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Michel Lagarde, Nathalie Bernoud-Hubac, Catherine Calzada, Evelyne Véricel, Michel Guichardant. Lipidomics of essential fatty acids and oxygenated metabolites.. Molecular Nutrition and Food Research, 2013, epub ahead of print. ⟨10.1002/mnfr.201200828⟩. ⟨inserm-00843903⟩
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