S. Aroui, S. Brahim, M. De-waard, J. Breard, and A. Kenani, Efficient induction of apoptosis by doxorubicin coupled to cell-penetrating peptides compared to unconjugated doxorubicin in the human breast cancer cell line MDA-MB 231, Cancer Letters, vol.285, issue.1, pp.28-38, 2009.
DOI : 10.1016/j.canlet.2009.04.044

URL : https://hal.archives-ouvertes.fr/inserm-00410230

S. Aroui, S. Brahim, M. De-waard, and A. Kenani, Cytotoxicity, intracellular distribution and uptake of doxorubicin and doxorubicin coupled to cell-penetrating peptides in different cell lines: A comparative study, Biochemical and Biophysical Research Communications, vol.391, issue.1, pp.419-425, 2010.
DOI : 10.1016/j.bbrc.2009.11.073

URL : https://hal.archives-ouvertes.fr/inserm-00587567

P. Lundberg, U. Langel, M. Mano, C. Teodosio, A. Paiva et al., Pharmaceuticals (Basel) 3, 1093?1107 33 221?296 is shown on top. Residues are in yellow. Shown also are the basic face (basic amino acid residues are in blue or in pink) and the pharmacophore (residues identified as interacting with the ryanodine receptor are in red or in pink) Pink residues belong both to the pharmacophore and the basic face. (B) Confocal microscopy images illustrating the penetration of four different peptides labeled with Cy5 at various concentrations into glioma F98 cells (blue color) Incubation times were 2 hrs for each peptide/concentration, Dose-dependent penetration of each peptide-cargo complex in F98 cells as assessed by flow cytometry. A control C-Cy5 is also provided. (D), 1969.

U. Chtx, 12 -C-Cy5 as determined by confocal microscopy (right panel) Quantitative analysis of F98 ChTx UF1-12 -C-Cy5 fluorescence as determined by flow cytometry. Internalization of the ChTx UF1-12 -C-Cy5 peptide is lower than