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Multiple players in mouse B cell memory.

Abstract : B cell memory has long been considered the attribute of the sole IgG-positive B cell subset. Since a few years, and due to new B-cell subset identification procedures, increasing heterogeneity has been identified among the memory B cell pool. IgM-positive cells and germinal center-independent subsets are recent additions to the field. This review describes the diversity of memory B cells, as well as controversial issues on their relative contribution to the recall response. The impact of a protracted germinal center response to the specific mobilization of IgM memory B cells is proposed.
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Submitted on : Monday, June 17, 2013 - 7:02:38 PM
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Jean-Claude Weill, Simon Le Gallou, yi Hao, Claude-Agnès Reynaud. Multiple players in mouse B cell memory.. Current Opinion in Immunology, Elsevier, 2013, 25 (3), epub ahead of print. ⟨10.1016/j.coi.2013.05.004⟩. ⟨inserm-00835011⟩



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