Study of a dual-mode array integrated in a multi-element transducer for imaging and therapy of prostate cancer

Jean-Martial Mari 1 Guillaume Bouchoux 1 Jean-Louis Dillenseger 2 Sophie Gimonet 3 Alain Birer 1 Carole Garnier 2 Lucie Brasset 1 Ke Wu 2 Jean-Luc Guey 3 Gérard Fleury 3 Jean-Yves Chapelon 1 Emmanuel Blanc 4, *
* Auteur correspondant
1 LabTAU - Application des ultrasons à la thérapie
2 LTSI - Laboratoire Traitement du Signal et de l'Image
3 Imasonic SAS [Voray sur l’Ognon]
4 EDAP - EDAP TMS France
Abstract : The development of endocavitary dual-mode probes is essential for the accurate treatment of many deep seated cancers which require a high imaging resolution and the capacity to selectively treat focal areas in the region of interest. The MULTIP project is aimed at using state-of-art piezoelectric technologies to design dual-mode ultrasonic probes for cancer-foci treatment and monitoring. In order to allow an efficient surgery planning, the technical study has been accompanied by a volume processing study permitting the design of the ultrasonic imaging/therapy process based on high-resolutionhigh-quality MRI images. Several prototypes were designed based on a simulation study and implemented: 1) two successive wide-band dual-mode transducer allowing imaging at high resolution (6 MHz) on a wide field of view, and therapy at 3 MHz with a good transduction efficiency (48% and 70%); 2) a therapy-only transducer matrix adapted to the desired curvature with a high transduction efficiency (70%). Finally, a registration study of MRI volumes on ultrasound volumes has shown that, because of the texture of the ultrasound images, it is more efficient to search at registering the surfaces of the volumes once they have been segmented in each modality, rather than trying to register the two data volumes directly.
Keywords : Ultrasound HIFU dual mode multi-element focal therapy prostate cancer
Type de document :
Article dans une revue
IRBM, Elsevier Masson, 2013, 34 (2), pp.147-158. 〈10.1016/j.irbm.2013.01.007〉
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http://www.hal.inserm.fr/inserm-00825309
Contributeur : Jean-Louis Dillenseger <>
Soumis le : jeudi 23 mai 2013 - 14:13:10
Dernière modification le : mercredi 16 mai 2018 - 11:23:41
Document(s) archivé(s) le : samedi 24 août 2013 - 06:15:10

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LTSI | LSIS | LSIS-GMOD | UNIV-LYON1 | UNIV-RENNES

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Jean-Martial Mari, Guillaume Bouchoux, Jean-Louis Dillenseger, Sophie Gimonet, Alain Birer, et al.. Study of a dual-mode array integrated in a multi-element transducer for imaging and therapy of prostate cancer. IRBM, Elsevier Masson, 2013, 34 (2), pp.147-158. 〈10.1016/j.irbm.2013.01.007〉. 〈inserm-00825309〉

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