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Extravasation of liposomal doxorubicin induces irritant reaction without vesicant injury.

Abstract : Anthracycline extravasation is an uncommon but very serious complication. Very few data are available in the literature concerning the consequences and the management of extravasation of liposomal doxorubicin. This report describes the cases of two patients with liposomal doxorubicin extravasation who developed irritant reaction without vesicant or necrotic lesions. It is concordant with other cases described in the literature and suggests that extravasation of liposomal doxorubicin can be relatively well tolerated. The process applied to extravasations of irritant and non-vesicant agents could be used to manage extravasations of liposomal doxorubicin.
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https://www.hal.inserm.fr/inserm-00821491
Contributor : Philippe Saas <>
Submitted on : Friday, May 10, 2013 - 2:20:09 PM
Last modification on : Wednesday, September 16, 2020 - 10:43:36 AM

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  • HAL Id : inserm-00821491, version 1
  • PUBMED : 22493389

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Elsa Curtit, Loïc Chaigneau, Julien Pauchot, Thierry Nguyen, Virginie Nerich, et al.. Extravasation of liposomal doxorubicin induces irritant reaction without vesicant injury.. Anticancer Research, International Institute of Anticancer Research, 2012, 32 (4), pp.1481-3. ⟨inserm-00821491⟩

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