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Journal articles
Extravasation of liposomal doxorubicin induces irritant reaction without vesicant injury.
Elsa Curtit
1, 2, 3, *
Loïc Chaigneau
1
Julien Pauchot
2, 4, 5
Thierry Nguyen
1
Virginie Nerich
2, 3, 6
Fernando Bazan
1
Antoine Thiery-Vuillemin
1, 2, 3
Martin Demarchi
1
Xavier Pivot
1, 2, 3
Cristian Villanueva
1
*
Corresponding author
Elsa Curtit 1, 2, 3
Correspondent author
Loïc Chaigneau 1
Author
Julien Pauchot 2, 4, 5
Author
Thierry Nguyen 1
Author
Virginie Nerich 2, 3, 6
Author
Fernando Bazan 1
Author
Antoine Thiery-Vuillemin 1, 2, 3
Author
Martin Demarchi 1
Author
Xavier Pivot 1, 2, 3
Author
Cristian Villanueva 1
Author
1
Service d'oncologie Médicale (France)
2
UFC - Université de Franche-Comté (1 rue Goudimel
25030 Besançon cedex - France)
3
RIGHT - Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098) (I.B.C.T.
Bâtiment Inserm
240 Route de Dole/Rue F. Dolto
25000 Besançon - France)
- INSERM - Institut National de la Santé et de la Recherche Médicale : U1098 (101, rue de Tolbiac, 75013 Paris - France)
- EFS [Bourgogne-Franche-Comté] - Etablissement français du sang [Bourgogne-Franche-Comté] (1 Boulevard Fleming 25020 Besançon cedex - France)
- UFC - Université de Franche-Comté (1 rue Goudimel 25030 Besançon cedex - France)
4
I4S - Intervention, innovation, imagerie, ingénierie en santé - UFC (UFR SMP, Besançon - France)
- UFC - Université de Franche-Comté : EA4268 (1 rue Goudimel 25030 Besançon cedex - France)
5
Service de Chirurgie Orthopédique Traumatologique et Plastique [Besançon] (3 bld Alexandre Fleming 25030 Besançon Cedex - France)
- CHRU Besançon - Centre Hospitalier Régional Universitaire [Besançon] (France)
- Hôpital Jean Minjoz (France)
- UFC - Université de Franche-Comté (1 rue Goudimel 25030 Besançon cedex - France)
6
Pharmacie à usage interne (Pôle Santé de Châteaufarine - 25000 Besançon - France)
Abstract : Anthracycline extravasation is an uncommon but very serious complication. Very few data are available in the literature concerning the consequences and the management of extravasation of liposomal doxorubicin. This report describes the cases of two patients with liposomal doxorubicin extravasation who developed irritant reaction without vesicant or necrotic lesions. It is concordant with other cases described in the literature and suggests that extravasation of liposomal doxorubicin can be relatively well tolerated. The process applied to extravasations of irritant and non-vesicant agents could be used to manage extravasations of liposomal doxorubicin.
Document type :
Journal articles
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https://www.hal.inserm.fr/inserm-00821491
Contributor : Philippe Saas Connect in order to contact the contributor
Submitted on : Friday, May 10, 2013 - 2:20:09 PM
Last modification on : Monday, October 11, 2021 - 10:04:58 AM
Contributor : Philippe Saas Connect in order to contact the contributor
Submitted on : Friday, May 10, 2013 - 2:20:09 PM
Last modification on : Monday, October 11, 2021 - 10:04:58 AM
Identifiers
- HAL Id : inserm-00821491, version 1
- PUBMED : 22493389
Collections
INSERM | UNIV-FCOMTE | UMR645
Citation
Elsa Curtit, Loïc Chaigneau, Julien Pauchot, Thierry Nguyen, Virginie Nerich, et al.. Extravasation of liposomal doxorubicin induces irritant reaction without vesicant injury.. Anticancer Research, International Institute of Anticancer Research, 2012, 32 (4), pp.1481-3. ⟨inserm-00821491⟩
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