B. Gumbiner, Breaking through the tight junction barrier, The Journal of Cell Biology, vol.123, issue.6, pp.1631-1633, 1993.
DOI : 10.1083/jcb.123.6.1631

E. Schneeberger and R. Lynch, The tight junction: a multifunctional complex, AJP: Cell Physiology, vol.286, issue.6, pp.1213-1228, 2004.
DOI : 10.1152/ajpcell.00558.2003

M. Dym and D. Fawcett, The Blood-Testis Barrier in the Rat and the Physiological Compartmentation of the Seminiferous Epithelium1, Biology of Reproduction, vol.3, issue.3, pp.308-326, 1970.
DOI : 10.1093/biolreprod/3.3.308

C. Flickinger and D. Fawcett, The junctional specializations of sertoli cells in the seminiferous epithelium, The Anatomical Record, vol.25, issue.2, pp.207-221, 1967.
DOI : 10.1002/ar.1091580210

L. Nicander, An electron microscopical study of cell contacts in the seminiferous tubules of some mammals, Zeitschrift f???r Zellforschung und Mikroskopische Anatomie, vol.17, issue.3, pp.375-397, 1967.
DOI : 10.1007/BF00336866

L. Russell, Observations on rat sertoli ectoplasmic (???junctional???) specializations in their association with germ cells of the rat testis, Tissue and Cell, vol.9, issue.3, pp.475-498, 1977.
DOI : 10.1016/0040-8166(77)90007-6

J. Brokelmann, Fine structure of germ cells and Sertoli cells during the cycle of the seminiferous epithelium in the rat, Zeitschrift f???r Zellforschung und Mikroskopische Anatomie, vol.7, issue.4, pp.820-850, 1963.
DOI : 10.1007/BF00362263

B. Masri, L. Russell, and A. Vogl, Distribution of actin in spermatids and adjacent sertoli cell regions of the rat, The Anatomical Record, vol.215, issue.1, pp.20-26, 1987.
DOI : 10.1002/ar.1092180105

L. Romrell and M. Ross, Characterization of Sertoli cell-germ cell junctional specializations in dissociated testicular cells, The Anatomical Record, vol.7, issue.1, pp.23-41, 1979.
DOI : 10.1002/ar.1091930103

L. Russell, J. Goh, R. Rashed, and A. Vogl, The Consequences of Actin Disruption at Sertoli Ectoplasmic Specialization Sites Facing Spermatids after in Vivo Exposure of Rat Testis to Cytochalasin D1, Biology of Reproduction, vol.39, issue.1, pp.105-118, 1988.
DOI : 10.1095/biolreprod39.1.105

A. Vogl, B. Grove, and G. Lew, Distribution of actin in sertoli cell ectoplasmic specializations and associated spermatids in the ground squirrel testis, The Anatomical Record, vol.4, issue.4, pp.331-341, 1986.
DOI : 10.1002/ar.1092150402

A. Vogl, D. Pfeiffer, D. Mulholland, G. Kimel, and J. Guttman, Unique and Multifunctional Adhesion Junctions in the Testis. Ectoplasmic Specializations., Archives of Histology and Cytology, vol.63, issue.1, pp.1-15, 2000.
DOI : 10.1679/aohc.63.1

A. Vogl and L. Soucy, Arrangement and possible function of actin filament bundles in ectoplasmic specializations of ground squirrel Sertoli cells, The Journal of Cell Biology, vol.100, issue.3, pp.814-825, 1985.
DOI : 10.1083/jcb.100.3.814

J. Weber, T. Turner, K. Tung, and L. Russell, Effects of cytochalasin D on the integrity of the Sertoli cell (blood-testis) barrier, American Journal of Anatomy, vol.IV, issue.2, pp.130-147, 1988.
DOI : 10.1002/aja.1001820204

W. Lui and C. Cheng, Regulation of cell junction dynamics by cytokines in the testis???A molecular and biochemical perspective, Cytokine & Growth Factor Reviews, vol.18, issue.3-4, pp.299-311, 2007.
DOI : 10.1016/j.cytogfr.2007.04.009

M. Mirza, C. Petersen, K. Nordqvist, and K. Sollerbrant, Coxsackievirus and Adenovirus Receptor Is Up-Regulated in Migratory Germ Cells during Passage of the Blood-Testis Barrier, Endocrinology, vol.148, issue.11, pp.5459-5469, 2007.
DOI : 10.1210/en.2007-0359

V. Cooke, M. Naik, and U. Naik, Fibroblast Growth Factor-2 Failed to Induce Angiogenesis in Junctional Adhesion Molecule-A-Deficient Mice, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.26, issue.9, pp.2005-2011, 2006.
DOI : 10.1161/01.ATV.0000234923.79173.99

M. Saitou, M. Furuse, H. Sasaki, J. Schulzke, M. Fromm et al., Complex Phenotype of Mice Lacking Occludin, a Component of Tight Junction Strands, Molecular Biology of the Cell, vol.11, issue.12, pp.4131-4142, 2000.
DOI : 10.1091/mbc.11.12.4131

A. Gow, C. Southwood, J. Li, M. Pariali, G. Riordan et al., CNS Myelin and Sertoli Cell Tight Junction Strands Are Absent in Osp/Claudin-11 Null Mice, Cell, vol.99, issue.6, pp.649-659, 1999.
DOI : 10.1016/S0092-8674(00)81553-6

J. Devaux and A. Gow, Tight junctions potentiate the insulative properties of small CNS myelinated axons, The Journal of Cell Biology, vol.181, issue.5, pp.909-921, 2008.
DOI : 10.1083/jcb.200712154

A. Gow, C. Davies, C. Southwood, G. Frolenkov, M. Chrustowski et al., Deafness in Claudin 11-Null Mice Reveals the Critical Contribution of Basal Cell Tight Junctions to Stria Vascularis Function, Journal of Neuroscience, vol.24, issue.32, pp.7051-7062, 2004.
DOI : 10.1523/JNEUROSCI.1640-04.2004

E. Wang, L. Miller, G. Ohnmacht, E. Liu, and F. Marincola, High-fidelity mRNA amplification for gene profiling, Nat Biotechnol, vol.18, pp.457-459, 2000.

G. Churchill, Fundamentals of experimental design for cDNA microarrays, Nature Genetics, vol.32, issue.Supp, pp.490-495, 2002.
DOI : 10.1038/ng1031

V. Tusher, R. Tibshirani, and G. Chu, Significance analysis of microarrays applied to the ionizing radiation response, Proceedings of the National Academy of Sciences, vol.98, issue.9, pp.5116-5121, 2001.
DOI : 10.1073/pnas.091062498

B. Zhang, S. Kirov, and J. Snoddy, WebGestalt: an integrated system for exploring gene sets in various biological contexts, Nucleic Acids Research, vol.33, issue.Web Server, pp.741-748, 2005.
DOI : 10.1093/nar/gki475

E. Oakberg, Duration of spermatogenesis in the mouse and timing of stages of the cycle of the seminiferous epithelium, American Journal of Anatomy, vol.106, issue.3, pp.507-516, 1956.
DOI : 10.1002/aja.1000990307

Y. Toyooka, N. Tsunekawa, Y. Takahashi, Y. Matsui, M. Satoh et al., Expression and intracellular localization of mouse Vasa-homologue protein during germ cell development, Mechanisms of Development, vol.93, issue.1-2, pp.139-149, 2000.
DOI : 10.1016/S0925-4773(00)00283-5

Y. Fujiwara, T. Komiya, H. Kawabata, M. Sato, H. Fujimoto et al., Isolation of a DEAD-family protein gene that encodes a murine homolog of Drosophila vasa and its specific expression in germ cell lineage., Proceedings of the National Academy of Sciences, vol.91, issue.25, pp.12258-12262, 1994.
DOI : 10.1073/pnas.91.25.12258

T. Noce, Y. Fujiwara, M. Sezaki, H. Fujimoto, and T. Higashinakagawa, Expression of a mouse zinc finger protein gene in both spermatocytes and oocytes during meiosis, Developmental Biology, vol.153, issue.2, pp.356-367, 1992.
DOI : 10.1016/0012-1606(92)90120-6

K. Yoshinaga, I. Tanii, and K. Toshimori, Molecular Chaperone Calmegin Localization to the Endoplasmic Reticulum of Meiotic and Post-meiotic Germ Cells in the Mouse Testis., Archives of Histology and Cytology, vol.62, issue.3, pp.283-293, 1999.
DOI : 10.1679/aohc.62.283

D. Watanabe, K. Sawada, U. Koshimizu, T. Kagawa, and Y. Nishimune, Characterization of male meiotic germ cell-specific antigen (Meg 1) by monoclonal antibody TRA 369 in mice, Molecular Reproduction and Development, vol.7, issue.3, pp.307-312, 1992.
DOI : 10.1002/mrd.1080330312

L. Magueresse-battistoni and B. , Serine proteases and serine protease inhibitors in testicular physiology: the plasminogen activation system, Reproduction, vol.134, issue.6, pp.721-729, 2007.
DOI : 10.1530/REP-07-0114

I. Ketola, N. Rahman, J. Toppari, M. Bielinska, S. Porter-tinge et al., Expression and Regulation of Transcription Factors GATA-4 and GATA-6 in Developing Mouse Testis, Endocrinology, vol.140, issue.3, pp.1470-1480, 1999.
DOI : 10.1210/en.140.3.1470

R. Viger, C. Mertineit, J. Trasler, and M. Nemer, Transcription factor GATA- 4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Mullerian inhibiting substance promoter, Development, vol.125, pp.2665-2675, 1998.

C. Print and K. Loveland, Germ cell suicide: new insights into apoptosis during spermatogenesis, BioEssays, vol.51, issue.5, pp.423-430, 2000.
DOI : 10.1002/(SICI)1521-1878(200005)22:5<423::AID-BIES4>3.0.CO;2-0

J. Cobb, M. Miyaike, A. Kikuchi, and M. Handel, Meiotic events at the centromeric heterochromatin: histone H3 phosphorylation, topoisomerase II?? localization and chromosome condensation, Chromosoma, vol.108, issue.7, pp.412-425, 1999.
DOI : 10.1007/s004120050393

P. Kluin, M. Kramer, and D. De-rooij, Proliferation of spermatogonia and Sertoli cells in maturing mice, Anatomy and Embryology, vol.4, issue.1, pp.73-78, 1984.
DOI : 10.1007/BF00300588

R. Vergouwen, S. Jacobs, R. Huiskamp, J. Davids, and D. De-rooij, Proliferative activity of gonocytes, Sertoli cells and interstitial cells during testicular development in mice, Reproduction, vol.93, issue.1, pp.233-243, 1991.
DOI : 10.1530/jrf.0.0930233

H. Cooke and P. Saunders, Mouse models of male infertility, Nature Reviews Genetics, vol.21, issue.10, pp.790-801, 2002.
DOI : 10.1038/nrg911

K. Toshimori, C. Ito, M. Maekawa, Y. Toyama, F. Suzuki-toyota et al., Impairment of spermatogenesis leading to infertility, Anatomical Science International, vol.99, issue.3, pp.101-111, 2004.
DOI : 10.1126/science.1059188

Y. Toyama, M. Maekawa, and S. Yuasa, Ectoplasmic specializations in the Sertoli cell: new vistas based on genetic defects and testicular toxicology, Anatomical Science International, vol.47, issue.1, pp.1-16, 2003.
DOI : 10.1083/jcb.136.2.399

M. Kopecky, V. Semecky, and P. Nachtigal, Vimentin expression during altered spermatogenesis in rats, Acta Histochemica, vol.107, issue.4, pp.279-289, 2005.
DOI : 10.1016/j.acthis.2005.06.007

B. Schrans-stassen, P. Saunders, H. Cooke, and D. De-rooij, Nature of the Spermatogenic Arrest in Dazl ???/??? Mice, Biology of Reproduction, vol.65, issue.3, pp.771-776, 2001.
DOI : 10.1095/biolreprod65.3.771

R. Wang, S. Yeh, L. Chen, H. Lin, C. Zhang et al., Androgen Receptor in Sertoli Cell Is Essential for Germ Cell Nursery and Junctional Complex Formation in Mouse Testes, Endocrinology, vol.147, issue.12, pp.5624-5633, 2006.
DOI : 10.1210/en.2006-0138

Z. Yu, N. Dadgar, M. Albertelli, A. Scheller, R. Albin et al., Abnormalities of Germ Cell Maturation and Sertoli Cell Cytoskeleton in Androgen Receptor 113 CAG Knock-In Mice Reveal Toxic Effects of the Mutant Protein, The American Journal of Pathology, vol.168, issue.1, pp.195-204, 2006.
DOI : 10.2353/ajpath.2006.050619

E. Sasso-cerri and P. Cerri, Morphological evidences indicate that the interference of cimetidine on the peritubular components is responsible for detachment and apoptosis of Sertoli cells, Reproductive Biology and Endocrinology, vol.6, issue.1, p.18, 2008.
DOI : 10.1186/1477-7827-6-18

T. Kaitu-'u-lino, P. Sluka, C. Foo, and P. Stanton, Claudin-11 expression and localisation is regulated by androgens in rat Sertoli cells in vitro, Reproduction, vol.133, issue.6, pp.1169-1179, 2007.
DOI : 10.1530/REP-06-0385

A. Beverdam, T. Svingen, S. Bagheri-fam, P. Bernard, P. Mcclive et al., Sox9-dependent expression of Gstm6 in Sertoli cells during testis development in mice, Reproduction, vol.137, issue.3, pp.481-486, 2009.
DOI : 10.1530/REP-08-0336

S. Mukherjee, S. Aravinda, B. Gopalakrishnan, S. Nagpal, D. Salunke et al., Secretion of glutathione S-transferase isoforms in the seminiferous tubular fluid, tissue distribution and sex steroid binding by rat GSTM1, Biochemical Journal, vol.340, issue.1, pp.309-320, 1999.
DOI : 10.1042/bj3400309

K. Fulcher, J. Welch, D. Klapper, O. Brien, D. Eddy et al., Identification of a unique ?-class glutathione S-transferase in mouse spermatogenic cells, Molecular Reproduction and Development, vol.19, issue.4, pp.415-424, 1995.
DOI : 10.1002/mrd.1080420407

K. Hewitt, R. Agarwal, and P. Morin, The claudin gene family: expression in normal and neoplastic tissues, BMC Cancer, vol.121, issue.1, p.186, 2006.
DOI : 10.1309/K144PHVDDUPDD401

S. Oliveira and J. Morgado-diaz, Claudins: multifunctional players in epithelial tight junctions and their role in cancer, Cellular and Molecular Life Sciences, vol.64, issue.1, pp.17-28, 2007.
DOI : 10.1007/s00018-006-6314-1

K. Swisshelm, R. Macek, and M. Kubbies, Role of claudins in tumorigenesis, Advanced Drug Delivery Reviews, vol.57, issue.6, pp.919-928, 2005.
DOI : 10.1016/j.addr.2005.01.006

L. Benbrahim-tallaa, B. Siddeek, A. Bozec, V. Tronchon, A. Florin et al., Alterations of Sertoli cell activity in the long-term testicular germ cell death process induced by fetal androgen disruption, Journal of Endocrinology, vol.196, issue.1, pp.21-31, 2008.
DOI : 10.1677/JOE-07-0062

F. Bauche, M. Fouchard, and B. Jegou, Antioxidant system in rat testicular cells, FEBS Letters, vol.193, issue.3, pp.392-396, 1994.
DOI : 10.1016/0014-5793(94)00709-8

J. Beckman and J. Coniglio, A comparative study of the lipid composition of isolated rat sertoli and germinal cells, Lipids, vol.91, issue.3, pp.262-267, 1979.
DOI : 10.1007/BF02533912

R. Franco, R. Sanchez-olea, E. Reyes-reyes, and M. Panayiotidis, Environmental toxicity, oxidative stress and apoptosis: M??nage ?? Trois, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, vol.674, issue.1-2, pp.3-22, 2009.
DOI : 10.1016/j.mrgentox.2008.11.012

S. Byers, R. Graham, H. Dai, and B. Hoxter, Development of Sertoli cell junctional specializations and the distribution of the tight-junction-associated protein ZO-1 in the mouse testis, American Journal of Anatomy, vol.176, issue.1, pp.35-47, 1991.
DOI : 10.1002/aja.1001910104

E. Ahmed, A. Barten-van-rijbroek, H. Kal, H. Sadri-ardekani, S. Mizrak et al., Proliferative Activity In Vitro and DNA Repair Indicate that Adult Mouse and Human Sertoli Cells Are Not Terminally Differentiated, Quiescent Cells1, Biology of Reproduction, vol.80, issue.6, pp.1084-1091, 2009.
DOI : 10.1095/biolreprod.108.071662

J. Gilleron, D. Carette, P. Durand, G. Pointis, and D. Segretain, Connexin 43 a potential regulator of cell proliferation and apoptosis within the seminiferous epithelium, The International Journal of Biochemistry & Cell Biology, vol.41, issue.6, pp.1381-1390, 2009.
DOI : 10.1016/j.biocel.2008.12.008

H. Iida, M. Noda, T. Kaneko, M. Doiguchi, and T. Mori, Identification of rab12 as a vesicle-associated small GTPase highly expressed in Sertoli cells of rat testis, Molecular Reproduction and Development, vol.264, issue.2, pp.178-185, 2005.
DOI : 10.1002/mrd.20294

D. Session, M. Fautsch, R. Avula, W. Jones, A. Nehra et al., Cyclin-dependent kinase 5 is expressed in both sertoli cells and metaphase spermatocytes, Fertility and Sterility, vol.75, issue.4, pp.669-673, 2001.
DOI : 10.1016/S0015-0282(00)01794-5

D. Chapman and D. Wolgemuth, Isolation of the murine cyclin B2 cDNA and characterization of the lineage and temporal specificity of expression of the B1 and B2 cyclins during oogenesis, spermatogenesis and early embryogenesis, Development, vol.118, pp.229-240, 1993.

D. Liu, M. Matzuk, W. Sung, Q. Guo, P. Wang et al., Cyclin A1 is required for meiosis in the male mouse, Nat Genet, vol.20, pp.377-380, 1998.

R. Sharpe, C. Mckinnell, C. Kivlin, and J. Fisher, Proliferation and functional maturation of Sertoli cells, and their relevance to disorders of testis function in adulthood, Reproduction, vol.125, issue.6, pp.769-784, 2003.
DOI : 10.1530/rep.0.1250769

D. Britt, D. Yang, D. Yang, D. Flanagan, H. Callanan et al., Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells, Experimental Cell Research, vol.300, issue.1, pp.134-148, 2004.
DOI : 10.1016/j.yexcr.2004.06.026

R. Young, Sex cord-stromal tumors of the ovary and testis: their similarities and differences with consideration of selected problems, Modern Pathology, vol.11, issue.2, pp.81-98, 2005.
DOI : 10.1038/modpathol.3800311

R. Young, Testicular tumors?some new and a few perennial problems, Arch Pathol Lab Med, vol.132, pp.548-564, 2008.

J. Meng, R. Holdcraft, J. Shima, M. Griswold, and R. Braun, Androgens regulate the permeability of the blood-testis barrier, Proceedings of the National Academy of Sciences, vol.102, issue.46, pp.16696-16700, 2005.
DOI : 10.1073/pnas.0506084102

I. Fritz, K. Burdzy, B. Setchell, and O. Blaschuk, Ram Rete Testis Fluid Contains a Protein (Clusterin) Which Influences Cell-Cell Interactions in Vitro 1, Biology of Reproduction, vol.28, issue.5, pp.1173-1188, 1983.
DOI : 10.1095/biolreprod28.5.1173

S. Magre and A. Jost, The initial phases of testicular organogenesis in the rat. An electron microscopy study, Arch Anat Microsc Morphol Exp, vol.69, pp.297-318, 1980.

L. Guillemot and S. Citi, Cingulin Regulates Claudin-2 Expression and Cell Proliferation through the Small GTPase RhoA, Molecular Biology of the Cell, vol.17, issue.8, pp.3569-3577, 2006.
DOI : 10.1091/mbc.E06-02-0122

K. Matter, S. Aijaz, A. Tsapara, and M. Balda, Mammalian tight junctions in the regulation of epithelial differentiation and proliferation, Current Opinion in Cell Biology, vol.17, issue.5, pp.453-458, 2005.
DOI : 10.1016/j.ceb.2005.08.003