E. Altman, D. Hedeker, J. Peterson, and J. Davis, The Altman Self-Rating Mania Scale, Biological Psychiatry, vol.42, issue.10, pp.948-5510, 1997.
DOI : 10.1016/S0006-3223(96)00548-3

. American-psychiatric-association, Diagnostic and statistical manual of mental disorders American Psychiatric Association: Text Revision, 2000.

E. Baca-garcia, M. Perez-rodriguez, I. Basurte-villamor, J. Lopez-castroman, F. Del-moral et al., Diagnostic stability and evolution of bipolar disorder in clinical practice: a prospective cohort study, Acta Psychiatrica Scandinavica, vol.96, issue.6, pp.473-80, 2007.
DOI : 10.1186/1745-0179-1-2

M. Bauer, K. Biswas, and A. Kilbourne, Enhancing Multiyear Guideline Concordance for Bipolar Disorder Through Collaborative Care, American Journal of Psychiatry, vol.166, issue.11, 2009.
DOI : 10.1176/appi.ajp.2009.09030342

J. Bostwick and V. Pankratz, Affective Disorders and Suicide Risk: A Reexamination, American Journal of Psychiatry, vol.157, issue.12, pp.1925-1957, 1925.
DOI : 10.1176/appi.ajp.157.12.1925

C. Chang, R. Hayes, G. Perera, M. Broadbent, A. Fernandes et al., Life Expectancy at Birth for People with Serious Mental Illness and Other Major Disorders from a Secondary Mental Health Care Case Register in London, PLoS ONE, vol.22, issue.5, 2011.
DOI : 10.1371/journal.pone.0019590.t002

F. Colom, E. Vieta, C. Daban, I. Pacchiarotti, and J. Sanchez-moreno, Clinical and therapeutic implications of predominant polarity in bipolar disorder, Journal of Affective Disorders, vol.93, issue.1-3, pp.1-3, 2006.
DOI : 10.1016/j.jad.2006.01.032

R. Dutta, J. Boydell, N. Kennedy, O. Van, P. Fearon et al., Suicide and other causes of mortality in bipolar disorder: a longitudinal study, Psychological Medicine, vol.37, issue.06, pp.839-886, 2007.
DOI : 10.1017/S0033291707000347

M. First, R. Spitzer, M. Gibbon, and J. Williams, Structured clinical interview for DSM- IV-TR Axis I Disorders, Research Version, Patient Edition (SCID-I/P), Biometrics Research, 2002.

B. Fischl and A. Dale, Measuring the thickness of the human cerebral cortex from magnetic resonance images, Proceedings of the National Academy of Sciences, vol.97, issue.20, pp.11050-11055, 2000.
DOI : 10.1073/pnas.200033797

I. Forcada, E. Papachristou, M. Mur, T. Christodoulou, J. Jogia et al., The impact of general intellectual ability and white matter volume on the functional outcome of patients with Bipolar Disorder and their relatives, Journal of Affective Disorders, vol.130, issue.3, pp.413-433, 2011.
DOI : 10.1016/j.jad.2010.10.048

M. Frye, T. Ketter, G. Leverich, T. Huggins, C. Lantz et al., The Increasing Use of Polypharmacotherapy for Refractory Mood Disorders, The Journal of Clinical Psychiatry, vol.61, issue.1, pp.9-15, 2000.
DOI : 10.4088/JCP.v61n0104

M. Gitlin, J. Swendsen, T. Heller, and C. Hammen, Relapse and impairment in bipolar disorder, The American Journal of Psychiatry, vol.152, issue.11, pp.1635-1675, 1995.

G. Goodwin, Evidence-based guidelines for treating bipolar disorder: revised second edition--recommendations from the British Association for Psychopharmacology, Journal of Psychopharmacology, vol.23, issue.4, pp.346-88, 2009.
DOI : 10.1177/0269881109102919

G. Goodwin, A. Martinez-aran, D. Glahn, and E. Vieta, Cognitive impairment in bipolar disorder: Neurodevelopment or neurodegeneration? An ECNP expert meeting report, European Neuropsychopharmacology, vol.18, issue.11, pp.787-93, 2008.
DOI : 10.1016/j.euroneuro.2008.07.005

C. Henry, B. Etain, F. Mathieu, A. Raust, J. Vibert et al., A French network of bipolar expert centres: A model to close the gap between evidence-based medicine and routine practice, Journal of Affective Disorders, vol.131, issue.1-3, pp.358-63, 2011.
DOI : 10.1016/j.jad.2010.11.013

R. Hirschfeld, L. Lewis, and L. Vornik, Perceptions and Impact of Bipolar Disorder, The Journal of Clinical Psychiatry, vol.64, issue.2, pp.161-74, 2003.
DOI : 10.4088/JCP.v64n0209

L. Kessing, H. Hansen, and A. Hvenegaard, Treatment in a specialised out-patient mood disorder clinic v. standard out-patient treatment in the early course of bipolar disorder: randomised clinical trial, The British Journal of Psychiatry, vol.202, issue.3, pp.212-221, 2013.
DOI : 10.1192/bjp.bp.112.113548

M. Leboyer and D. Kupfer, Bipolar Disorder, The Journal of Clinical Psychiatry, vol.71, issue.12, pp.1689-95, 2010.
DOI : 10.4088/JCP.10m06347yel

URL : https://hal.archives-ouvertes.fr/inserm-00951733

A. Lopez and C. Murray, The global burden of disease, 1990???2020, Nature Medicine, vol.72, issue.11, pp.1241-1244, 1990.
DOI : 10.1016/S0140-6736(97)03360-6

T. Marteau and H. Bekker, The development of a six-item short-form of the state scale of the Spielberger State-Trait Anxiety Inventory (STAI), British Journal of Clinical Psychology, vol.31, issue.3, 1992.
DOI : 10.1111/j.2044-8260.1992.tb00997.x

A. Martinez-aran, J. Scott, F. Colom, C. Torrent, R. Tabares-seisdedos et al., Treatment Nonadherence and Neurocognitive Impairment in Bipolar Disorder, The Journal of Clinical Psychiatry, vol.70, issue.7, pp.1017-1040, 2009.
DOI : 10.4088/JCP.08m04408

K. Merikangas, H. Akiskal, J. Angst, P. Greenberg, R. Hirschfeld et al., Lifetime and 12-Month Prevalence of Bipolar Spectrum Disorder in the National Comorbidity Survey Replication, Archives of General Psychiatry, vol.64, issue.5, pp.543-52, 2007.
DOI : 10.1001/archpsyc.64.5.543

D. Miklowitz and J. Scott, Psychosocial treatments for bipolar disorder: cost-effectiveness, mediating mechanisms, and future directions, Bipolar Disorders, vol.2, issue.2, pp.110-132, 2009.
DOI : 10.1111/j.1399-5618.2009.00715.x

S. Montgomery and M. Åsberg, A new depression scale designed to be sensitive to change, The British Journal of Psychiatry, vol.134, issue.4, pp.382-391, 1979.
DOI : 10.1192/bjp.134.4.382

B. Müller-oerlinghausen, A. Berghofer, and M. Bauer, Bipolar disorder, The Lancet, vol.359, issue.9302, pp.241-248, 2002.
DOI : 10.1016/S0140-6736(02)07450-0

A. Nivoli, F. Colom, A. Murru, I. Pacchiarotti, P. Castro-loli et al., New treatment guidelines for acute bipolar depression: A systematic review, Journal of Affective Disorders, vol.129, issue.1-3, pp.14-26, 2011.
DOI : 10.1016/j.jad.2010.05.018

A. Nivoli, A. Murru, J. Goikolea, J. Crespo, J. Montes et al., New treatment guidelines for acute bipolar mania: A critical review, Journal of Affective Disorders, vol.140, issue.2, pp.125-166, 2011.
DOI : 10.1016/j.jad.2011.10.015

E. Pontin, S. Peters, F. Lobban, A. Rogers, and R. Morriss, Enhanced relapse prevention for bipolar disorder: a qualitative investigation of value perceived for service users and care coordinators, Implementation Science, vol.53, issue.1, pp.4-10, 2009.
DOI : 10.1016/S0738-3991(03)00114-9

L. Rimol, C. Hartberg, R. Nesvag, C. Fennema-notestine, D. Hagler et al., Cortical Thickness and Subcortical Volumes in Schizophrenia and Bipolar Disorder, Biological Psychiatry, vol.68, issue.1, pp.41-50, 2010.
DOI : 10.1016/j.biopsych.2010.03.036

A. Rosa, J. Sanchez-moreno, A. Martinez-aran, M. Salamero, C. Torrent et al., Validity and reliability of the Functioning Assessment Short Test (FAST) in bipolar disorder, Clinical Practice and Epidemiology in Mental Health, vol.3, issue.1, pp.5-10, 2007.
DOI : 10.1186/1745-0179-3-5

A. Rosa, M. Reinares, B. Amann, D. Popovic, C. Franco et al., Six-month functional outcome of a bipolar disorder cohort in the context of a specialized-care program, Bipolar Disorders, vol.127, issue.7-8, pp.679-86, 2011.
DOI : 10.1111/j.1399-5618.2011.00964.x

A. Rush, M. Trivedi, H. Ibrahim, T. Carmody, B. Arnow et al., The 16-Item quick inventory of depressive symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression, Biological Psychiatry, vol.54, issue.5, pp.573-83, 2003.
DOI : 10.1016/S0006-3223(02)01866-8

J. Scott, Bipolar Disorders, pp.89-90, 2011.
DOI : 10.1002/9780470713242.ch18

URL : https://hal.archives-ouvertes.fr/inserm-00769159

J. Scott and M. Leboyer, Consequences of mis-diagnosis of bipolar disorder. L'encephale, 2012.

J. Scott, E. Paykel, R. Morriss, R. Bentall, P. Kinderman et al., Cognitive-behavioural therapy for severe and recurrent bipolar disorders: Randomised controlled trial, The British Journal of Psychiatry, vol.188, issue.4, pp.313-333, 2006.
DOI : 10.1192/bjp.188.4.313

D. Sheehan, Y. Lecrubier, K. Sheehan, P. Amorim, J. Janavs et al., The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10, The Journal of Clinical Psychiatry, vol.59, pp.22-33, 1998.

E. Vieta, I. Pacchiarotti, M. Valenti, L. Berk, J. Scott et al., A critical update on psychological interventions for bipolar disorders, Current Psychiatry Reports, vol.78, issue.Suppl5, pp.494-502, 2009.
DOI : 10.1007/s11920-009-0075-0

E. Vieta and M. Phillips, Deconstructing Bipolar Disorder: A Critical Review of its Diagnostic Validity and a Proposal for DSM-V and ICD-11, Schizophrenia Bulletin, vol.33, issue.4, pp.886-92, 2007.
DOI : 10.1093/schbul/sbm057

V. Pascual, E. , T. Font, C. Martínez-arán, A. et al., Escala sencilla de evaluación del curso del trastorno bipolar: CGI-BP -M, Actas Esp Psiquiat, vol.30, issue.5, pp.301-305, 2002.

E. Vieta, E. Blasco-colmenares, M. Figueira, J. Langosch, M. Moreno-manzanaro et al., Clinical management and burden of bipolar disorder: results from a multinational longitudinal study (WAVE-bd), The International Journal of Neuropsychopharmacology, vol.16, issue.08, p.58, 2011.
DOI : 10.1017/S1461145713000278

E. Vieta, Bipolar units and programmes: are they really needed? World Psychiatry, p.152, 2011.

E. Vieta and N. Cruz, Head to head comparisons as an alternative to placebo-controlled trials, European Neuropsychopharmacology, vol.22, issue.11, pp.800-803, 2012.
DOI : 10.1016/j.euroneuro.2011.11.011

J. Olesen, A. Gustavsson, M. Svensson, H. Wittchen, and B. Jönsson, The economic cost of brain disorders in Europe, European Journal of Neurology, vol.21, issue.Suppl. 14, pp.155-62, 2012.
DOI : 10.1111/j.1468-1331.2011.03590.x

M. Wolfsperger, W. Greil, W. Rossler, and R. Grohmann, Pharmacological treatment of acute mania in psychiatric in-patients between, J Affect Disord, vol.99, pp.1-3, 1994.

R. Young, J. Biggs, V. Ziegler, and D. Meyer, A rating scale for mania: reliability, validity and sensitivity, The British Journal of Psychiatry, vol.133, issue.5, pp.429-464, 1978.
DOI : 10.1192/bjp.133.5.429

. Henry, European Network of Bipolar Research Expert Centre (ENBREC): a network to foster research and promote innovative care, Submit your manuscript to a journal and benefi t from: 7 Convenient online submission 7 Rigorous peer review 7 Immediate publication on acceptance 7 Open access: articles freely available online 7 High visibility within the fi eld 7 Retaining the copyright to your article Submit your next manuscript at 7 springeropen, 2013.
DOI : 10.1192/bjp.133.5.429

URL : https://hal.archives-ouvertes.fr/inserm-00814543