Mucins in cancer: protection and control of the cell surface The MUC family: an obituary, Nat Rev Cancer Trends Biochem Sci, vol.43, issue.27, pp.45-60, 2002. ,
Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization Characterization of human mucin 5B gene expression in airway epithelium and the genomic clone of the amino-terminal and 5'-flanking region Normal respiratory mucosa, precursor lesions and lung carcinomas: differential expression of human mucin genes, J Histochem Cytochem Am J Respir Cell Mol Biol Front Biosci, vol.4156, issue.6, pp.1479-85, 1993. ,
The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers Respiratory tract mucin genes and mucin glycoproteins in health and disease, Biochimie Physiol Rev, vol.928, issue.86, pp.1-11, 2006. ,
Developmental Mucin Gene Expression in the Human Respiratory Tract, American Journal of Respiratory Cell and Molecular Biology, vol.20, issue.2, pp.209-227, 1998. ,
DOI : 10.1165/ajrcmb.20.2.3259
From normal respiratory mucosa to epidermoid carcinoma: Expression of human mucin genes, International Journal of Cancer, vol.53, issue.2, pp.162-170, 2000. ,
DOI : 10.1002/(SICI)1097-0215(20000415)86:2<162::AID-IJC3>3.0.CO;2-R
The mouse Muc5b mucin gene: cDNA and genomic structures, chromosomal localization and expression, Biochemical Journal, vol.363, issue.3, pp.589-98, 2002. ,
DOI : 10.1042/bj3630589
Mucinous bronchioloalveolar carcinomas display a specific pattern of mucin gene expression among primary lung adenocarcinomas, Human Pathology, vol.32, issue.3, pp.274-81, 2001. ,
DOI : 10.1053/hupa.2001.22752
Transcriptional regulation of the 11p15 mucin genes towards new biological tools in human therapy in inflammatory diseases and cancer, Frontiers in Bioscience, vol.6, issue.3, pp.1216-1250, 2001. ,
DOI : 10.2741/A675
Human MUC2 Mucin Gene Is Transcriptionally Regulated by Cdx Homeodomain Proteins in Gastrointestinal Carcinoma Cell Lines, Journal of Biological Chemistry, vol.278, issue.51, pp.51549-56, 2003. ,
DOI : 10.1074/jbc.M309019200
The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells, Biochemical and Biophysical Research Communications, vol.325, issue.3, pp.952-60, 2004. ,
DOI : 10.1016/j.bbrc.2004.10.108
The Human Mucin MUC4 Is Transcriptionally Regulated by Caudal-related Homeobox, Hepatocyte Nuclear Factors, Forkhead Box A, and GATA Endodermal Transcription Factors in Epithelial Cancer Cells, Journal of Biological Chemistry, vol.282, issue.31, pp.22638-50, 2007. ,
DOI : 10.1074/jbc.M700905200
Transcription factors and pattern formation in the developing lung, Am J Physiol, vol.269, pp.429-471, 1995. ,
Transcription factors in mouse lung development and function, Am J Physiol Lung Cell Mol Physiol, vol.280, pp.823-861, 2001. ,
The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary., Genes & Development, vol.10, issue.1, pp.60-69, 1996. ,
DOI : 10.1101/gad.10.1.60
Transcriptional Control of Lung Morphogenesis, Physiological Reviews, vol.87, issue.1, pp.219-263, 2007. ,
DOI : 10.1152/physrev.00028.2006
GATA-6 and Thyroid Transcription Factor-1 Directly Interact and Regulate Surfactant Protein-C Gene Expression, Journal of Biological Chemistry, vol.277, issue.6, pp.4519-4544, 2002. ,
DOI : 10.1074/jbc.M107585200
Regulation of Clara cell secretory protein gene transcription by thyroid transcription factor-1, Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, vol.1350, issue.3, pp.359-67, 1997. ,
DOI : 10.1016/S0167-4781(96)00180-7
Transcriptional regulation of a mouse Clara cell-specific protein (mCC10) gene by the NKx transcription factor family members thyroid transciption factor 1 and cardiac muscle-specific homeobox protein (CSX)., Molecular and Cellular Biology, vol.16, issue.5, pp.2056-64, 1996. ,
DOI : 10.1128/MCB.16.5.2056
Mucins in the pathophysiological lung Expression and roles in immuno-and gene-based therapies in: The Epithelial Mucins: Structure/Function, Roles in Cancer and Inflammatory Diseases Research Signpost, pp.109-124, 2008. ,
The Zinc Finger-containing Transcription Factors GATA-4, -5, and -6: UBIQUITOUSLY EXPRESSED REGULATORS OF TISSUE-SPECIFIC GENE EXPRESSION, Journal of Biological Chemistry, vol.275, issue.50, pp.38949-52, 2000. ,
DOI : 10.1074/jbc.R000029200
GATA-6: A Zinc Finger Transcription Factor That Is Expressed in Multiple Cell Lineages Derived from Lateral Mesoderm, Developmental Biology, vol.177, issue.1, pp.309-331, 1996. ,
DOI : 10.1006/dbio.1996.0165
GATA-5: A Transcriptional Activator Expressed in a Novel Temporally and Spatially-Restricted Pattern during Embryonic Development, Developmental Biology, vol.183, issue.1, pp.21-36, 1997. ,
DOI : 10.1006/dbio.1996.8485
The WNT7b Promoter Is Regulated by TTF-1, GATA6, and Foxa2 in Lung Epithelium, Journal of Biological Chemistry, vol.277, issue.23, pp.21061-70, 2002. ,
DOI : 10.1074/jbc.M111702200
Sequence of the 5???-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells, Biochemical Journal, vol.348, issue.3, pp.675-86, 2000. ,
DOI : 10.1042/bj3480675
Thyroid transcription factor-1 expression prevalence and its clinical implications in non-small cell lung cancer: a high-throughput tissue microarray and immunohistochemistry study, Human Pathology, vol.34, issue.6, pp.597-604, 2003. ,
DOI : 10.1016/S0046-8177(03)00180-1
Pulmonary well-differentiated fetal adenocarcinoma expressing lineage-specific transcription factors (TTF-1 and GATA-6) to respiratory epithelial Page 21 of 34 FEBS Journal differentiation: an immunohistochemical and ultrastructural study, Virchows Arch, vol.442, pp.393-402, 2003. ,
Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is potentiated by Sp1, Biochemical Journal, vol.377, issue.3, pp.797-808, 2004. ,
DOI : 10.1042/bj20030948
Induction of MUC2 and MUC5AC Mucins by Factors of the Epidermal Growth Factor (EGF) Family Is Mediated by EGF Receptor/Ras/Raf/Extracellular Signal-regulated Kinase Cascade and Sp1*, Journal of Biological Chemistry, vol.277, issue.35, pp.32258-67, 2002. ,
DOI : 10.1074/jbc.M204862200
Aberrant Expression of Human Mucin GeneMUC5B in Gastric Carcinoma and Cancer Cells: IDENTIFICATION AND REGULATION OF A DISTAL PROMOTER, Journal of Biological Chemistry, vol.276, issue.18, pp.15386-96, 2001. ,
DOI : 10.1074/jbc.M010534200
Mechanisms of Gene Expression and Cell Fate Determination in the Developing Pulmonary Epithelium, Annual Review of Physiology, vol.58, issue.1, pp.51-71, 1996. ,
DOI : 10.1146/annurev.ph.58.030196.000411
Series Introduction: Intrinsic and innate defenses in the lung: intersection of pathways regulating lung morphogenesis, host defense, and repair, Journal of Clinical Investigation, vol.109, issue.5, pp.565-574, 2002. ,
DOI : 10.1172/JCI0215209
Expression of Thyroid Transcription Factor-1 in Normal and Neoplastic Lung Tissues, Modern Pathology, vol.15, issue.10, pp.1058-67, 2002. ,
DOI : 10.1097/01.MP.0000028572.44247.CF
Different mucins are produced by the surface epithelium and the submucosa in human trachea: identification of MUC5AC as a major mucin from the goblet cells, Biochemical Journal, vol.318, issue.1, pp.318-319, 1996. ,
DOI : 10.1042/bj3180319
Developmental Competence of the Gut Endoderm: Genetic Potentiation by GATA and HNF3/Fork Head Proteins, Developmental Biology, vol.209, issue.1, pp.1-10, 1999. ,
DOI : 10.1006/dbio.1999.9228
Hypermethylation of the GATA Genes in Lung Cancer, Clinical Cancer Research, vol.10, issue.23, pp.7917-7941, 2004. ,
DOI : 10.1158/1078-0432.CCR-04-1140
Anomalous expression of epithelial differentiation-determining GATA factors in ovarian tumorigenesis, Cancer Res, vol.63, pp.4967-77, 2003. ,
Transcription factor GATA-5 selectively up-regulates mucin gene expression, Journal of Cancer Research and Clinical Oncology, vol.130, issue.5, pp.245-52, 2004. ,
DOI : 10.1007/s00432-003-0537-4
Mucin expression and regulation during development and cell differentiation in: The Epithelial Mucins: Structure/Function, Roles in Cancer and Inflammatory Diseases Research Signpost, pp.75-94, 2008. ,
Temporal/spatial expression of nuclear receptor coactivators in the mouse lung, Am J Physiol Lung Cell Mol Physiol, vol.279, pp.1066-74, 2000. ,
GATA6 regulates differentiation of distal lung epithelium, pp.2233-2279, 2002. ,
The K protein domain that recruits the interleukin 1-responsive K protein kinase lies, 1995. ,