Airway Remodeling in Asthma, Chest, vol.123, issue.3, pp.417-422, 2003. ,
DOI : 10.1378/chest.123.3_suppl.417S
Tissue remodeling as a feature of persistent asthma, Journal of Allergy and Clinical Immunology, vol.105, issue.6, pp.1041-1053, 2000. ,
DOI : 10.1067/mai.2000.107195
Airway Structural Alterations Selectively Associated with Severe Asthma, American Journal of Respiratory and Critical Care Medicine, vol.167, issue.10, pp.1360-1368, 2003. ,
DOI : 10.1164/rccm.200209-1030OC
Airway Remodeling in Asthma, Allergology International, vol.56, issue.4, pp.341-348, 2007. ,
DOI : 10.2332/allergolint.R-07-153
SUBEPITHELIAL FIBROSIS IN THE BRONCHI OF ASTHMATICS, The Lancet, vol.333, issue.8637, pp.520-524, 1989. ,
DOI : 10.1016/S0140-6736(89)90067-6
Role of Extracellular Matrix and Its Regulators in Human Airway Smooth Muscle Biology, Cell Biochemistry and Biophysics, vol.44, issue.1, pp.139-146, 2006. ,
DOI : 10.1385/CBB:44:1:139
mRNA Expression and Airways Fibrosis in Bronchial Asthma, American Journal of Respiratory Cell and Molecular Biology, vol.17, issue.3, pp.326-333, 1997. ,
DOI : 10.1165/ajrcmb.17.3.2733
Anti-IL-5 treatment reduces deposition of ECM proteins in the bronchial subepithelial basement membrane of mild atopic asthmatics, Journal of Clinical Investigation, vol.112, issue.7, pp.1029-1036, 2003. ,
DOI : 10.1172/JCI17974
Transforming Growth Factor- ?? Expression in Mucosal Biopsies in Asthma and Chronic Bronchitis, American Journal of Respiratory and Critical Care Medicine, vol.156, issue.2, pp.591-599, 1997. ,
DOI : 10.1164/ajrccm.156.2.9609066
IL-11 expression is increased in severe asthma: Association with epithelial cells and eosinophils, Journal of Allergy and Clinical Immunology, vol.105, issue.2, pp.232-238, 2000. ,
DOI : 10.1016/S0091-6749(00)90070-8
Inhibition of airway remodeling in IL-5???deficient mice, Journal of Clinical Investigation, vol.113, issue.4, pp.551-560, 2004. ,
DOI : 10.1172/JCI19133
Eosinophil's Role Remains Uncertain as Anti???Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway, American Journal of Respiratory and Critical Care Medicine, vol.167, issue.2, pp.199-204, 2003. ,
DOI : 10.1164/rccm.200208-789OC
Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine, Respiratory Medicine, vol.97, issue.6, pp.726-733, 2003. ,
DOI : 10.1053/rmed.2003.1507
Interleukin-17F Induces Pulmonary Neutrophilia and Amplifies Antigen-induced Allergic Response, American Journal of Respiratory and Critical Care Medicine, vol.171, issue.1, pp.12-18, 2005. ,
DOI : 10.1164/rccm.200406-778OC
TH17 cytokines induce human airway smooth muscle cell migration, Journal of Allergy and Clinical Immunology, vol.127, issue.4, pp.1046-1053, 2011. ,
DOI : 10.1016/j.jaci.2010.12.1117
Molecular Mechanisms of Cytokine and Chemokine Release from Eosinophils Activated by IL-17A, IL-17F, and IL-23: Implication for Th17 Lymphocytes-Mediated Allergic Inflammation, The Journal of Immunology, vol.180, issue.8, pp.5625-5635, 2008. ,
DOI : 10.4049/jimmunol.180.8.5625
Human Eosinophils Constitutively Express a Functional Interleukin-4 Receptor: Interleukin-4??????Induced Priming of Chemotactic Responses and Induction of PI-3 Kinase Activity, American Journal of Respiratory Cell and Molecular Biology, vol.19, issue.4, pp.691-699, 1998. ,
DOI : 10.1165/ajrcmb.19.4.3208
Granulocytemacrophage colony-stimulating factor and interleukin-3 induce surface expression of interleukin-2 receptor p55-chain and CD4 by human eosinophils, Immunology, vol.70, pp.258-261, 1990. ,
TNF-?? and IFN-?? inversely modulate expression of the IL-17E receptor in airway smooth muscle cells, AJP: Lung Cellular and Molecular Physiology, vol.290, issue.6, pp.1238-1246, 2006. ,
DOI : 10.1152/ajplung.00301.2005
IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts, Journal of Allergy and Clinical Immunology, vol.117, issue.3, pp.590-596, 2006. ,
DOI : 10.1016/j.jaci.2005.10.025
Airway Hyperresponsiveness and Airway Obstruction in Transgenic Mice, American Journal of Respiratory Cell and Molecular Biology, vol.22, issue.3, pp.289-295, 2000. ,
DOI : 10.1165/ajrcmb.22.3.3690
IL-17 is increased in asthmatic airways and induces human bronchial fibroblasts to produce cytokines, Journal of Allergy and Clinical Immunology, vol.108, issue.3, pp.430-438, 2001. ,
DOI : 10.1067/mai.2001.117929
An improved immunomagnetic procedure for the isolation of highly purified human blood eosinophils, Journal of Immunological Methods, vol.145, issue.1-2, pp.105-110, 1991. ,
DOI : 10.1016/0022-1759(91)90315-7
Lidocaine and its analogues inhibit IL-5-mediated survival and activation of human eosinophils, J Immunol, vol.160, pp.4010-4017, 1998. ,
Analysis of relative gene expression data using real-time quantitative PCR and the 2(?Delta Delta C(T)) Method, pp.402-408, 2001. ,
To respond or not to respond: T cells in allergic asthma, Nature Reviews Immunology, vol.3, issue.5, pp.405-412, 2003. ,
DOI : 10.1038/nri1084
TH17-associated cytokines (IL-17A and IL-17F) in severe asthma, Journal of Allergy and Clinical Immunology, vol.123, issue.5, pp.1185-1187, 2009. ,
DOI : 10.1016/j.jaci.2009.02.024
Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patients, Thorax, vol.61, issue.3, pp.202-208, 2006. ,
DOI : 10.1136/thx.2005.052399
Role of Transforming Growth Factor????? in Airway Remodeling in Asthma, American Journal of Respiratory Cell and Molecular Biology, vol.44, issue.2, pp.127-133, 2011. ,
DOI : 10.1165/rcmb.2010-0027TR
TGF-?? Promotes Th17 Cell Development through Inhibition of SOCS3, The Journal of Immunology, vol.183, issue.1, pp.97-105, 2009. ,
DOI : 10.4049/jimmunol.0801986
TGF-?? is necessary for induction of IL-23R and Th17 differentiation by IL-6 and IL-23, Biochemical and Biophysical Research Communications, vol.386, issue.1, pp.105-110, 2009. ,
DOI : 10.1016/j.bbrc.2009.05.140
IL-21 and TGF-?? are required for differentiation of human TH17 cells, Nature, vol.282, issue.7202, pp.350-352, 2008. ,
DOI : 10.1038/nature07021
Cutting Edge: IL-17F, a Novel Cytokine Selectively Expressed in Activated T Cells and Monocytes, Regulates Angiogenesis and Endothelial Cell Cytokine Production, The Journal of Immunology, vol.167, issue.8, pp.4137-4140, 2001. ,
DOI : 10.4049/jimmunol.167.8.4137
IL-17 Promotes p38 MAPK-Dependent Endothelial Activation Enhancing Neutrophil Recruitment to Sites of Inflammation, The Journal of Immunology, vol.184, issue.8, pp.4531-4537, 2010. ,
DOI : 10.4049/jimmunol.0903162
IL-4-dependent regulation of TGF-alpha and TGF-beta1 expression in human eosinophils, J Immunol, vol.160, pp.6121-6127, 1998. ,
Interferon-?? Inhibits Transforming Growth Factor-?? Production in Human Airway Epithelial Cells by Targeting Smads, American Journal of Respiratory Cell and Molecular Biology, vol.30, issue.6, pp.816-822, 2004. ,
DOI : 10.1165/rcmb.2002-0249OC
Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis, J Clin Invest, vol.118, pp.479-490, 2008. ,
The Respiratory Burst Activity of Activated Eosinophils in Atopic Asthmatics, International Archives of Allergy and Immunology, vol.119, issue.1, pp.38-44, 1999. ,
DOI : 10.1159/000024173
Blood eosinophils and eosinophil-derived proteins in allergic asthma, Journal of Allergy and Clinical Immunology, vol.84, issue.6, pp.931-936, 1989. ,
DOI : 10.1016/0091-6749(89)90391-6
Increased CD69 expression on peripheral blood eosinophils after specific inhalation challenge, Allergy, vol.179, issue.5, pp.411-416, 2002. ,
DOI : 10.1067/mai.2000.106924
Serum IL-23 strongly and inversely correlates with FEV1 in asthmatic children, Int Arch Allergy Immunol, vol.159, pp.183-186, 2012. ,
Serum IL-23: a surrogate biomarker for asthma?, Clinical & Experimental Allergy, vol.126, issue.9, pp.1416-1417, 1418. ,
DOI : 10.1111/j.1365-2222.2012.04068.x
T Helper 17 Cells in Airway Diseases, Chest, vol.143, issue.2, pp.494-501, 2013. ,
DOI : 10.1378/chest.12-0598
Structure and signalling in the IL-17 receptor family, Nature Reviews Immunology, vol.452, issue.8, pp.556-567, 2009. ,
DOI : 10.1038/nri2586
IL-17A induces eotaxin-1/CC chemokine ligand 11 expression in human airway http://respiratory-research.com/content, 34 smooth muscle cells: role of MAPK (Erk1/2, JNK, and p38) pathways ,
Transcriptional and Translational Regulation of TGF-?? Production in Response to Apoptotic Cells, The Journal of Immunology, vol.181, issue.5, pp.3575-3585, 2008. ,
DOI : 10.4049/jimmunol.181.5.3575
Glucocorticoid resistance in inflammatory diseases, The Lancet, vol.373, issue.9678, pp.1905-1917, 2009. ,
DOI : 10.1016/S0140-6736(09)60326-3
p38 MAP-Kinases pathway regulation, function and role in human diseases, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1773, issue.8, pp.381358-1375, 2007. ,
DOI : 10.1016/j.bbamcr.2007.03.010