S. Johansson, T. Bieber, R. Dahl, P. Friedmann, B. Lanier et al., Revised Nomenclature for Allergy for Global Use, Allergy & Clinical Immunology International - Journal of the World Allergy Organization, vol.17, issue.01, pp.832-838, 2003.
DOI : 10.1027/0838-1925.17.1.4

J. Bousquet, J. Anto, C. Bachert, P. Bousquet, P. Colombo et al., Factors responsible for differences between asymptomatic subjects and patients presenting an IgE sensitization to allergens. A GA2LEN project, Allergy, vol.1, issue.6, pp.671-80, 2006.
DOI : 10.1385/CRIAI:26:2:093

C. Svanes, J. Sunyer, E. Plana, S. Dharmage, J. Heinrich et al., Early life origins of chronic obstructive pulmonary disease, Thorax, vol.65, issue.1, pp.14-20, 2010.
DOI : 10.1136/thx.2008.112136

H. Sampson, A. Munoz-furlong, R. Campbell, N. Adkinson, J. Bock et al., Second symposium on the definition and management of anaphylaxis: Summary report???Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium, Journal of Allergy and Clinical Immunology, vol.117, issue.2, pp.391-398, 2006.
DOI : 10.1016/j.jaci.2005.12.1303

P. Demoly, W. Pichler, M. Pirmohamed, and A. Romano, Important questions in Allergy: 1 - drug allergy/hypersensitivity, Allergy, vol.165, issue.5, pp.616-625, 2008.
DOI : 10.1111/j.1398-9995.2008.01693.x

S. Sicherer and H. Sampson, Food allergy, Journal of Allergy and Clinical Immunology, vol.125, issue.2, pp.116-141, 2010.
DOI : 10.1016/j.jaci.2009.08.028
URL : https://hal.archives-ouvertes.fr/hal-01262509

B. Bilo, F. Rueff, H. Mosbech, F. Bonifazi, and J. Oude-elberink, Diagnosis of Hymenoptera venom allergy, Allergy, vol.101, issue.74, pp.1339-1388, 2005.
DOI : 10.1046/j.1365-2222.1997.980914.x

B. Zuraw, Hereditary Angioedema, New England Journal of Medicine, vol.359, issue.10, pp.1027-1063, 2008.
DOI : 10.1056/NEJMcp0803977

K. Krause, T. Zuberbier, and M. Maurer, Modern approaches to the diagnosis and treatment of cold contact urticaria. Curr Allergy Asthma Rep, pp.243-252, 2010.

J. Roujeau, Clinical heterogeneity of drug hypersensitivity. Toxicology, Apr, vol.15209, issue.2, pp.123-132, 2005.

J. Bousquet, N. Khaltaev, A. Cruz, J. Denburg, W. Fokkens et al., Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen) Allergy, 2008.

J. Bousquet and N. Khaltaev, Global surveillance, prevention and control of Chronic Respiratory Diseases. A comprehensive approach. Global Alliance against Chronic Respiratory Diseases. World Health Organization, p.148, 2007.

T. Bieber, Atopic Dermatitis, New England Journal of Medicine, vol.358, issue.14, pp.1483-94, 2008.
DOI : 10.1056/NEJMra074081

N. Pearce, J. Pekkanen, and R. Beasley, How much asthma is really attributable to atopy? Thorax, pp.268-72, 1999.

G. Weinmayr, F. Forastiere, S. Weiland, P. Rzehak, T. Abramidze et al., International variation in prevalence of rhinitis and its relationship with sensitisation to perennial and seasonal allergens, European Respiratory Journal, vol.32, issue.5, 2008.
DOI : 10.1183/09031936.00157807
URL : https://hal.archives-ouvertes.fr/hal-00652964

P. Bousquet, B. Leynaert, F. Neukirch, J. Sunyer, C. Janson et al., Geographical distribution of atopic rhinitis in the European Community Respiratory Health Survey I. Allergy, pp.1301-1310, 2008.

J. Bousquet, W. Fokkens, P. Burney, S. Durham, C. Bachert et al., Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper, Allergy, vol.34, issue.Suppl. 1, pp.842-53, 2008.
DOI : 10.1111/j.1398-9995.2008.01715.x
URL : https://hal.archives-ouvertes.fr/hal-00409869

W. Fokkens, V. Lund, and M. J. Ep3os, European position paper on rhinosinusitis and nasal polyps, Rhinology, vol.45, pp.1-139, 2007.

C. Bachert, N. Van-bruaene, E. Toskala, N. Zhang, H. Olze et al., LEN study, Allergy, vol.61, issue.Suppl. 1, pp.520-553, 2009.
DOI : 10.1111/j.1398-9995.2009.01964.x

D. Hastan, W. Fokkens, C. Bachert, R. Newson, J. Bislimovska et al., Chronic rhinosinusitis in Europe an underestimated disease. A GA(2) LEN study. Allergy, 2011.

E. Edf, WAO guideline: definition, classification and diagnosis of urticaria, Allergy, issue.2, 2009.

E. Edf, WAO guideline: management of urticaria, Allergy, vol.64, issue.210, pp.1427-1470, 2009.

J. Bousquet, T. Clark, S. Hurd, N. Khaltaev, C. Lenfant et al., GINA guidelines on asthma and beyond. Allergy, Feb, vol.62, issue.2, pp.102-114, 2007.
DOI : 10.1111/j.1398-9995.2006.01305.x

D. Taylor, E. Bateman, L. Boulet, H. Boushey, W. Busse et al., A new perspective on concepts of asthma severity and control, European Respiratory Journal, vol.32, issue.3, pp.545-54, 2008.
DOI : 10.1183/09031936.00155307

J. Bousquet, E. Mantzouranis, A. Cruz, N. Ait-khaled, C. Baena-cagnani et al., Uniform definition of asthma severity, control, and exacerbations: Document presented for the World Health Organization Consultation on Severe Asthma, Journal of Allergy and Clinical Immunology, vol.126, issue.5, pp.926-964, 2010.
DOI : 10.1016/j.jaci.2010.07.019

J. Bousquet, J. Anto, P. Sterk, I. Adcock, K. Chung et al., Systems medicine and integrated care to combat chronic noncommunicable diseases, Genome Medicine, vol.3, issue.7, p.43, 2011.
DOI : 10.1186/gm259
URL : https://hal.archives-ouvertes.fr/hal-01358549

M. Humbert, S. Holgate, L. Boulet, and J. Bousquet, Asthma control or severity: that is the question, Allergy, vol.354, issue.2, 2007.
DOI : 10.1111/j.1398-9995.2006.01308.x

E. Bateman, S. Hurd, P. Barnes, J. Bousquet, J. Drazen et al., Global strategy for asthma management and prevention: GINA executive summary, European Respiratory Journal, vol.31, issue.1, pp.143-78, 2008.
DOI : 10.1183/09031936.00138707

M. Thomas, K. Gruffydd-jones, C. Stonham, S. Ward, and T. Macfarlane, Assessing asthma control in routine clinical practice: use of the Royal College of Physicians ???3 Questions???, Primary Care Respiratory Journal, vol.18, issue.2, 2008.
DOI : 10.3132/pcrj.2008.00045

E. Juniper, O. Byrne, P. Guyatt, G. Ferrie, P. King et al., Development and validation of a questionnaire to measure asthma control, European Respiratory Journal, vol.14, issue.4, pp.902-909, 1999.
DOI : 10.1034/j.1399-3003.1999.14d29.x

E. Juniper, J. Bousquet, L. Abetz, and E. Bateman, Identifying ???well-controlled??? and ???not well-controlled??? asthma using the Asthma Control Questionnaire, Respiratory Medicine, vol.100, issue.4, pp.616-637, 2006.
DOI : 10.1016/j.rmed.2005.08.012

R. Nathan, C. Sorkness, M. Kosinski, M. Schatz, J. Li et al., Development of the asthma control test???A survey for assessing asthma control, Journal of Allergy and Clinical Immunology, vol.113, issue.1, pp.59-65, 2004.
DOI : 10.1016/j.jaci.2003.09.008

M. Thomas, S. Kay, J. Pike, A. Williams, J. Rosenzweig et al., The Asthma Control TestTM (ACT) as a predictor of GINA guideline-defined asthma control: analysis of a multinational cross-sectional survey, Primary Care Respiratory Journal, vol.18, issue.1, pp.41-50, 2009.
DOI : 10.4104/pcrj.2009.00010

E. Juniper, K. Gruffydd-jones, S. Ward, and K. Svensson, Asthma Control Questionnaire in children: validation, measurement properties, interpretation, European Respiratory Journal, vol.36, issue.6, pp.1410-1416, 2010.
DOI : 10.1183/09031936.00117509

A. Liu, R. Zeiger, C. Sorkness, N. Ostrom, B. Chipps et al., The Childhood Asthma Control Test???: Retrospective determination and clinical validation of a cut point to identify children with very poorly controlled asthma, Journal of Allergy and Clinical Immunology, vol.126, issue.2, pp.267-73, 2010.
DOI : 10.1016/j.jaci.2010.05.031

T. Haahtela, L. Tuomisto, A. Pietinalho, T. Klaukka, M. Erhola et al., A 10 year asthma programme in Finland: major change for the better, Thorax, vol.61, issue.8, pp.663-70, 2006.
DOI : 10.1136/thx.2005.055699

C. Souza-machado, A. Souza-machado, R. Franco, E. Ponte, M. Barreto et al., Rapid reduction in hospitalisations after an intervention to manage severe asthma, European Respiratory Journal, vol.35, issue.3, pp.515-536, 2010.
DOI : 10.1183/09031936.00101009

W. Andrade, P. Camargos, L. Lasmar, and J. Bousquet, A pediatric asthma management program in a low-income setting resulting in reduced use of health service for acute asthma. Allergy, 2010.

R. Evans, P. Gergen, H. Mitchell, M. Kattan, C. Kercsmar et al., A randomized clinical trial to reduce asthma morbidity among inner-city children: Results of the National Cooperative Inner-City Asthma Study, The Journal of Pediatrics, vol.135, issue.3, pp.332-340, 1999.
DOI : 10.1016/S0022-3476(99)70130-7

M. Humbert, R. Beasley, J. Ayres, R. Slavin, J. Hebert et al., Benefits of omalizumab as add-on therapy in patients with severe persistent asthma who are inadequately controlled despite best available therapy (GINA 2002 step 4 treatment): INNOVATE, Allergy, vol.23, issue.(3 Pt 1), pp.309-325, 2005.
DOI : 10.1111/j.1398-9995.2004.00772.x

E. Bell, A. Sousa, L. Fleming, A. Bush, K. Chung et al., Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI), Thorax, vol.66, issue.10, 2011.
DOI : 10.1136/thx.2010.153643

J. Castro-rodriguez, C. Holberg, A. Wright, and F. Martinez, A Clinical Index to Define Risk of Asthma in Young Children with Recurrent Wheezing, American Journal of Respiratory and Critical Care Medicine, vol.162, issue.4, pp.1403-1409, 2000.
DOI : 10.1164/ajrccm.162.4.9912111

C. Devulapalli, K. Carlsen, G. Haland, M. Munthe-kaas, M. Pettersen et al., Severity of obstructive airways disease by age 2 years predicts asthma at 10 years of age, Thorax, vol.63, issue.1, pp.8-13, 2008.
DOI : 10.1136/thx.2006.060616

P. Brand, E. Baraldi, H. Bisgaard, A. Boner, J. Castro-rodriguez et al., Definition, assessment and treatment of wheezing disorders in preschool children: an evidence-based approach, European Respiratory Journal, vol.32, issue.4, 2008.
DOI : 10.1183/09031936.00002108

J. Bousquet, J. Anto, C. Auffray, M. Akdis, A. Cambon-thomsen et al., MeDALL (Mechanisms of the Development of ALLergy): an integrated approach from phenotypes to systems medicine, Allergy, vol.126, issue.Suppl. 1, 2011.
DOI : 10.1111/j.1398-9995.2010.02534.x
URL : https://hal.archives-ouvertes.fr/hal-00595853

A. Cameron, M. Ewen, D. Ross-degnan, D. Ball, and R. Laing, Medicine prices, availability, and affordability in 36 developing and middle-income countries: a secondary analysis, The Lancet, vol.373, issue.9659, pp.240-249, 2009.
DOI : 10.1016/S0140-6736(08)61762-6

J. Bousquet, C. Bachert, G. Canonica, T. Casale, A. Cruz et al., Unmet needs in severe chronic upper airway disease (SCUAD), Journal of Allergy and Clinical Immunology, vol.124, issue.3, pp.428-461, 2009.
DOI : 10.1016/j.jaci.2009.06.027

P. Bousquet, C. Combescure, F. Neukirch, J. Klossek, H. Mechin et al., Visual analog scales can assess the severity of rhinitis graded according to ARIA guidelines, Allergy, vol.29, issue.0, pp.367-72, 2007.
DOI : 10.1034/j.1398-9995.2002.03228.x

S. Ragab, V. Lund, H. Saleh, and G. Scadding, Nasal nitric oxide in objective evaluation of chronic rhinosinusitis therapy, Allergy, vol.117, issue.1, pp.717-741, 2006.
DOI : 10.1016/S0954-6111(98)90308-0

A. Valero, M. Ferrer, J. Sastre, A. Navarro, L. Monclus et al., A new criterion by which to discriminate between patients with moderate allergic rhinitis and patients with severe allergic rhinitis based on the Allergic Rhinitis and its Impact on Asthma severity items, Journal of Allergy and Clinical Immunology, vol.120, issue.2, pp.359-65, 2007.
DOI : 10.1016/j.jaci.2007.04.006

I. Baiardini, P. Bousquet, Z. Brzoza, G. Canonica, E. Compalati et al., Recommendations for assessing Patient-Reported Outcomes and Health-Related quality of life in clinical trials on allergy: a GA, 2009.

I. Baiardini, P. Bousquet, Z. Brzoza, G. Canonica, E. Compalati et al., LEN taskforce position paper, Allergy, vol.243, issue.Suppl. 2, pp.290-295, 2010.
DOI : 10.1111/j.1398-9995.2009.02263.x

M. Schatz, E. Meltzer, R. Nathan, M. Derebery, M. Mintz et al., Psychometric validation of the Rhinitis Control Assessment Test: a brief patient-completed instrument for evaluating rhinitis symptom control, Annals of Allergy, Asthma & Immunology, vol.104, issue.2, pp.118-142, 2010.
DOI : 10.1016/j.anai.2009.11.063

P. Bousquet, C. Combescure, J. Klossek, J. Daures, and J. Bousquet, Change in visual analog scale score in a pragmatic randomized cluster trial of allergic rhinitis, Journal of Allergy and Clinical Immunology, vol.123, issue.6, pp.1349-54, 2009.
DOI : 10.1016/j.jaci.2009.02.033

D. Ryan, C. Van-weel, J. Bousquet, E. Toskala, S. Ahlstedt et al., Primary care: the cornerstone of diagnosis of allergic rhinitis, Allergy, vol.108, issue.6760 Suppl, pp.981-990, 2008.
DOI : 10.1111/j.1398-9995.2008.01653.x

J. Bousquet, I. Annesi-maesano, F. Carat, D. Leger, M. Rugina et al., Characteristics of intermittent and persistent allergic rhinitis: DREAMS study group, Clinical <html_ent glyph="@amp;" ascii="&"/> Experimental Allergy, vol.96, issue.1, pp.728-760, 2005.
DOI : 10.1034/j.1398-9995.2001.00991.x

P. Bousquet, C. Bachert, G. Canonica, T. Casale, J. Mullol et al., Uncontrolled allergic rhinitis during treatment and its impact on quality of life: A??cluster randomized trial, Journal of Allergy and Clinical Immunology, vol.126, issue.3, pp.666-674, 2010.
DOI : 10.1016/j.jaci.2010.06.034

J. Bousquet, V. Lund, P. Van-cauwenberge, C. Bremard-oury, N. Mounedji et al., Implementation of guidelines for seasonal allergic rhinitis: a randomized controlled trial, Allergy, vol.54, issue.8, pp.733-774, 2003.
DOI : 10.1034/j.1398-9995.2002.03228.x

D. Webb, E. Meltzer, A. Finn, J. Rickard, K. Pepsin et al., Intranasal fluticasone propionate is effective for perennial nonallergic rhinitis with or without eosinophilia, Annals of Allergy, Asthma & Immunology, vol.88, issue.4, 2002.
DOI : 10.1016/S1081-1206(10)62369-1

A. Greiner and E. Meltzer, Pharmacologic rationale for treating allergic and nonallergic rhinitis, Journal of Allergy and Clinical Immunology, vol.118, issue.5, pp.985-98, 2006.
DOI : 10.1016/j.jaci.2006.06.029

J. Bousquet, P. Van-cauwenberge, and N. Khaltaev, Allergic Rhinitis and Its Impact on Asthma, Journal of Allergy and Clinical Immunology, vol.108, issue.5, pp.147-334, 2001.
DOI : 10.1067/mai.2001.118891
URL : https://hal.archives-ouvertes.fr/inserm-00815533

C. Rondon, J. Romero, S. Lopez, C. Antunez, E. Martin-casanez et al., Local IgE production and positive nasal provocation test in patients with persistent nonallergic rhinitis, Journal of Allergy and Clinical Immunology, vol.119, issue.4, pp.899-905, 2007.
DOI : 10.1016/j.jaci.2007.01.006

M. Dykewicz and S. Fineman, Executive Summary of Joint Task Force Practice Parameters on Diagnosis and Management of Rhinitis, Annals of Allergy, Asthma & Immunology, vol.81, issue.5, pp.463-471, 1998.
DOI : 10.1016/S1081-1206(10)63152-3

J. Bousquet, F. Neukirch, P. Bousquet, P. Gehano, J. Klossek et al., Severity and impairment of allergic rhinitis in patients consulting in primary care, Journal of Allergy and Clinical Immunology, vol.117, issue.1, pp.158-62, 2006.
DOI : 10.1016/j.jaci.2005.09.047

M. Blaiss, Allergic rhinitis and impairment issues in schoolchildren: a consensus report, Curr Med Res Opin, 2004.

F. Simons, Learning Impairment and Allergic Rhinitis, Allergy and Asthma Proceedings, vol.17, issue.4, pp.185-194, 1996.
DOI : 10.2500/108854196778996895

M. Church, M. Maurer, F. Simons, C. Bindslev-jensen, P. Van-cauwenberge et al., LEN position paper, Allergy, vol.64, issue.Suppl. 1, pp.459-66, 2010.
DOI : 10.1111/j.1398-9995.2009.02325.x

R. Shaaban, M. Zureik, D. Soussan, C. Neukirch, J. Heinrich et al., Rhinitis and onset of asthma: a longitudinal population-based study, The Lancet, vol.372, issue.9643, pp.1049-57, 2008.
DOI : 10.1016/S0140-6736(08)61446-4
URL : https://hal.archives-ouvertes.fr/inserm-00335310

M. Lim, S. Lew-gor, Y. Darby, N. Brookes, G. Scadding et al., The relationship between subjective assessment instruments in chronic rhinosinusitis, Rhinology, vol.45, issue.2, pp.144-151, 2007.

T. Van-zele, S. Claeys, P. Gevaert, G. Van-maele, G. Holtappels et al., Differentiation of chronic sinus diseases by measurement of inflammatory mediators, Allergy, vol.128, issue.11, pp.1280-1289, 2006.
DOI : 10.1002/ppul.1101

N. Zhang, T. Van-zele, C. Perez-novo, N. Van-bruaene, G. Holtappels et al., Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease, Journal of Allergy and Clinical Immunology, vol.122, issue.5, 2008.
DOI : 10.1016/j.jaci.2008.07.008

N. Van-bruaene, L. Derycke, C. Perez-novo, P. Gevaert, G. Holtappels et al., TGF-?? signaling and collagen deposition in chronic rhinosinusitis, Journal of Allergy and Clinical Immunology, vol.124, issue.2, pp.253-262, 2009.
DOI : 10.1016/j.jaci.2009.04.013

P. Stjarne, K. Blomgren, P. Caye-thomasen, S. Salo, and T. Soderstrom, The efficacy and safety of once-daily mometasone furoate nasal spray in nasal polyposis: a randomized, double-blind, placebo-controlled study, Acta Oto-Laryngologica, vol.109, issue.6, 2006.
DOI : 10.1016/S0091-6749(96)70119-7

J. Mullol, A. Obando, L. Pujols, and I. Alobid, Corticosteroid Treatment in Chronic Rhinosinusitis: The Possibilities and the Limits, Immunology and Allergy Clinics of North America, vol.29, issue.4, pp.657-68, 2009.
DOI : 10.1016/j.iac.2009.07.001

S. Vaidyanathan, M. Barnes, P. Williamson, P. Hopkinson, P. Donnan et al., Treatment of Chronic Rhinosinusitis With Nasal Polyposis With Oral Steroids Followed by Topical Steroids, Annals of Internal Medicine, vol.154, issue.5, pp.293-302, 2011.
DOI : 10.7326/0003-4819-154-5-201103010-00003

S. Vento, L. Ertama, M. Hytonen, C. Wolff, and C. Malmberg, Nasal polyposis: clinical course during 20 years, Annals of Allergy, Asthma & Immunology, vol.85, issue.3, pp.209-223, 2000.
DOI : 10.1016/S1081-1206(10)62468-4

I. Alobid, J. Guilemany, and J. Mullol, Nasal manifestations of systemic illnesses. Curr Allergy Asthma Rep, 2004.

C. Bachert, N. Zhang, G. Holtappels, D. Lobel, L. Van-cauwenberge et al., Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma, Journal of Allergy and Clinical Immunology, vol.126, issue.5, pp.962-970, 2010.
DOI : 10.1016/j.jaci.2010.07.007

M. Kowalski, J. Makowska, M. Blanca, S. Bavbek, G. Bochenek et al., Hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) - classification, diagnosis and management: review of the EAACI/ENDA# and GA2LEN/HANNA*, Allergy, vol.15, issue.Suppl 1, pp.818-847, 2011.
DOI : 10.1111/j.1398-9995.2011.02557.x

H. Fuchs and S. Tanner, Granulomatous disorders of the nose and paranasal sinuses. Curr Opin Otolaryngol Head Neck Surg, Feb, vol.17, issue.1, pp.23-30, 2009.

P. Bonfils, P. Halimi, and D. Malinvaud, Adrenal suppression and osteoporosis after treatment of nasal polyposis, Acta Oto-Laryngologica, vol.41, issue.53, pp.1195-200, 2006.
DOI : 10.1016/S0091-6749(99)70117-X

A. Kaplan and M. Greaves, Pathogenesis of chronic urticaria, Clinical & Experimental Allergy, vol.39, issue.6, pp.777-87, 2009.
DOI : 10.1111/j.1365-2222.2009.03256.x

M. Maurer, K. Weller, C. Bindslev-jensen, A. Gimenez-arnau, P. Bousquet et al., Allergy, Unmet clinical needs in chronic spontaneous urticaria. A GA(2) LEN task force report, 2010.

S. Mathias, S. Dreskin, A. Kaplan, S. Saini, S. Spector et al., Development of a daily diary for patients with chronic idiopathic urticaria, Annals of Allergy, Asthma & Immunology, vol.105, issue.2, pp.142-150, 2010.
DOI : 10.1016/j.anai.2010.06.011

A. Mlynek, A. Zalewska-janowska, P. Martus, P. Staubach, T. Zuberbier et al., How to assess disease activity in patients with chronic urticaria? Allergy, pp.777-80, 2008.

I. Baiardini, F. Braido, S. Brandi, and G. Canonica, Allergic diseases and their impact on quality of life, Annals of Allergy, Asthma & Immunology, vol.97, issue.4, pp.419-447, 2006.
DOI : 10.1016/S1081-1206(10)60928-3

L. Kropfl, M. Maurer, and T. Zuberbier, Treatment strategies in urticaria, Expert Opinion on Pharmacotherapy, vol.31, issue.1, pp.1445-50
DOI : 10.2165/00002018-200528120-00005

B. Neven, A. Prieur, and P. Quartier-dit-maire, Cryopyrinopathies: update on pathogenesis and treatment, Nature Clinical Practice Rheumatology, vol.105, issue.9, pp.481-490, 2008.
DOI : 10.1038/ncprheum0874

M. Soubrier, Schnitzler syndrome Joint Bone Spine, pp.263-269, 2008.
DOI : 10.1016/j.jbspin.2007.07.014

M. Magerl, E. Borzova, A. Gimenez-arnau, C. Grattan, F. Lawlor et al., LEN/EDF/UNEV consensus panel recommendations, Allergy, vol.229, issue.12, pp.1715-1736, 2009.
DOI : 10.1111/j.1398-9995.2009.02177.x

S. Dreskin and K. Andrews, The thyroid and urticaria, Current Opinion in Allergy and Clinical Immunology, vol.5, issue.5, pp.408-420, 2005.
DOI : 10.1097/01.all.0000182546.83465.5a

R. Willemsen, D. Roseeuw, and J. Vanderlinden, Alexithymia and dermatology: the state of the art, International Journal of Dermatology, vol.23, issue.9, 2008.
DOI : 10.1111/j.1365-4632.2008.03726.x

J. Hanifin, M. Thurston, M. Omoto, R. Cherill, S. Tofte et al., The eczema area and severity index (EASI): assessment of reliability in atopic dermatitis, Experimental Dermatology, vol.44, issue.1, pp.11-19, 2001.
DOI : 10.1111/1523-1747.ep12297659

J. Schmitt, S. Langan, and H. Williams, What are the best outcome measurements for??atopic eczema? A systematic review, Journal of Allergy and Clinical Immunology, vol.120, issue.6, pp.1389-98, 2007.
DOI : 10.1016/j.jaci.2007.08.011

G. Rajka and T. Langeland, Grading of the severity of atopic dermatitis, Acta Derm Venereol, vol.144, pp.13-17, 1989.

J. Stalder, S. Barbarot, A. Wollenberg, E. Holm, L. De-raeve et al., Patient-Oriented SCORAD (PO-SCORAD): a new self-assessment scale in atopic dermatitis validated in Europe, Allergy, vol.27, issue.8, 2011.
DOI : 10.1111/j.1398-9995.2011.02577.x

S. Van-velsen, M. Knol, I. Haeck, C. Bruijnzeel-koomen, and S. Pasmans, The Self-Administered Eczema Area and Severity Index in Children with Moderate to Severe Atopic Dermatitis: Better Estimation of AD Body Surface Area Than Severity, Pediatric Dermatology, vol.218, issue.Suppl, pp.470-475, 2010.
DOI : 10.1111/j.1525-1470.2010.01285.x

S. Alanne, M. Nermes, R. Soderlund, and K. Laitinen, Quality of life in infants with atopic dermatitis and healthy infants: a follow-up from birth to 24 months. Acta Paediatr, 2011.

B. Rehal and A. Armstrong, Health Outcome Measures in Atopic Dermatitis: A Systematic Review of Trends in Disease Severity and Quality-of-Life Instruments 1985???2010, PLoS ONE, vol.136, issue.Suppl 48, p.17520, 2011.
DOI : 10.1371/journal.pone.0017520.t002

H. Saeki, M. Furue, F. Furukawa, M. Hide, M. Ohtsuki et al., Guidelines for management of atopic dermatitis, The Journal of Dermatology, vol.117, issue.Suppl 63, pp.563-77, 2009.
DOI : 10.1111/j.1346-8138.2009.00706.x

U. Darsow, A. Wollenberg, D. Simon, A. Taieb, T. Werfel et al., ETFAD/EADV eczema task force 2009 position paper on diagnosis and treatment of atopic dermatitis, Journal of the European Academy of Dermatology and Venereology, vol.142, issue.Suppl., pp.317-345, 2010.
DOI : 10.1111/j.1468-3083.2009.03415.x

J. Bos, Atopiform dermatitis, British Journal of Dermatology, vol.104, issue.3, pp.426-435, 2002.
DOI : 10.1016/S0140-6736(96)91556-1

A. Filipovich, K. Mcclain, and A. Grom, Histiocytic Disorders: Recent Insights into Pathophysiology and Practical Guidelines, Biology of Blood and Marrow Transplantation, vol.16, issue.1, pp.82-91, 2010.
DOI : 10.1016/j.bbmt.2009.11.014
URL : http://doi.org/10.1016/j.bbmt.2009.11.014

R. Clark and R. Fuhlbrigge, Immunology and Skin Disease 2009: Frontiers in Cutaneous Immunology, Journal of Investigative Dermatology, vol.129, issue.8, pp.1849-51, 2009.
DOI : 10.1038/jid.2009.166

D. Leung, Preface to atopic dermatitis intervention to control the atopic march, Journal of Allergy and Clinical Immunology, vol.112, issue.6, 2003.
DOI : 10.1016/j.jaci.2003.09.034

S. Illi, E. Von-mutius, S. Lau, R. Nickel, C. Gruber et al., The natural course of atopic dermatitis from birth to age 7 years and the association with asthma???, Journal of Allergy and Clinical Immunology, vol.113, issue.5, pp.925-956, 2004.
DOI : 10.1016/j.jaci.2004.01.778

J. Spergel, Epidemiology of Atopic Dermatitis and Atopic March in Children. Immunol Allergy Clin North Am, 2010.

S. Brown, Y. Asai, H. Cordell, L. Campbell, Y. Zhao et al., Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy, Journal of Allergy and Clinical Immunology, vol.127, issue.3, pp.661-668, 2011.
DOI : 10.1016/j.jaci.2011.01.031

D. Von-bubnoff, E. Andres, F. Hentges, T. Bieber, T. Michel et al., Natural killer cells in atopic and autoimmune diseases of the skin, Journal of Allergy and Clinical Immunology, vol.125, issue.1, pp.60-68, 2010.
DOI : 10.1016/j.jaci.2009.11.020

P. Ong and D. Leung, The infectious aspects of atopic dermatitis. Immunol Allergy Clin North Am, 2010.

T. Shiohara, Y. Sato, R. Takahashi, M. Kurata, and Y. Mizukawa, Increased Susceptibility to Cutaneous Viral Infections in Atopic Dermatitis: The Roles of Regulatory T Cells and Innate Immune Defects, Curr Probl Dermatol, vol.41, pp.125-160, 2011.
DOI : 10.1159/000323306

L. Fonacier and M. Aquino, The role of contact allergy in atopic dermatitis. Immunol Allergy Clin North Am, 2010.

A. Lang, K. Carlsen, G. Haaland, C. Devulapalli, M. Munthe-kaas et al., Severe asthma in childhood: assessed in 10year olds in a birth cohort study, Allergy, vol.121, issue.6 pt 1, pp.1054-60, 2008.
DOI : 10.1111/j.1398-9995.2008.01672.x

A. Lang, P. Mowinckel, C. Sachs-olsen, A. Riiser, J. Lunde et al., Asthma severity in childhood, untangling clinical phenotypes. Pediatr Allergy Immunol, pp.945-53, 2010.

A. Fitzpatrick, W. Teague, D. Meyers, S. Peters, X. Li et al., Heterogeneity of severe asthma in childhood: Confirmation by cluster analysis of children in the National Institutes of Health/National Heart, Lung, and Blood Institute Severe Asthma Research Program, Journal of Allergy and Clinical Immunology, vol.127, issue.2, pp.382-391, 2011.
DOI : 10.1016/j.jaci.2010.11.015

L. Carlsen, K. Hedlin, G. Bush, A. Wennergren, G. De-benedictis et al., Assessment of problematic severe asthma in children, European Respiratory Journal, vol.37, issue.2, pp.432-472, 2011.
DOI : 10.1183/09031936.00091410

S. Walker, S. Khan-wasti, M. Fletcher, P. Cullinan, J. Harris et al., Seasonal allergic rhinitis is associated with a detrimental effect on examination performance in United Kingdom teenagers: Case-control study, Journal of Allergy and Clinical Immunology, vol.120, issue.2, pp.381-388, 2007.
DOI : 10.1016/j.jaci.2007.03.034

S. Balzar, M. Fajt, S. Comhair, S. Erzurum, E. Bleecker et al., Mast Cell Phenotype, Location, and Activation in Severe Asthma, American Journal of Respiratory and Critical Care Medicine, vol.183, issue.3, pp.299-309, 2011.
DOI : 10.1164/rccm.201002-0295OC

W. Moore, D. Meyers, S. Wenzel, W. Teague, H. Li et al., Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program, Am J Respir Crit Care Med Feb, vol.15181, issue.4, pp.315-338, 2010.

C. Auffray, I. Adcock, K. Chung, R. Djukanovic, C. Pison et al., An Integrative Systems Biology Approach to Understanding Pulmonary Diseases, Chest, vol.137, issue.6, pp.1410-1416, 2010.
DOI : 10.1378/chest.09-1850

J. Lotvall, C. Akdis, L. Bacharier, L. Bjermer, T. Casale et al., Asthma endotypes: A??new approach to classification of disease entities within the asthma syndrome, Journal of Allergy and Clinical Immunology, vol.127, issue.2, pp.355-60, 2011.
DOI : 10.1016/j.jaci.2010.11.037

A. Brasier, S. Victor, G. Boetticher, H. Ju, C. Lee et al., Molecular phenotyping of severe asthma using pattern recognition of bronchoalveolar lavage???derived cytokines, Journal of Allergy and Clinical Immunology, vol.121, issue.1, pp.30-37, 2008.
DOI : 10.1016/j.jaci.2007.10.015

M. Miller, C. Johnson, D. Miller, Y. Deniz, E. Bleecker et al., Severity assessment in asthma: An evolving concept, Journal of Allergy and Clinical Immunology, vol.116, issue.5, pp.990-995, 2005.
DOI : 10.1016/j.jaci.2005.08.018

S. Wenzel, Asthma: defining of the persistent adult phenotypes, The Lancet, vol.368, issue.9537, pp.804-817, 2006.
DOI : 10.1016/S0140-6736(06)69290-8

P. Haldar, I. Pavord, D. Shaw, M. Berry, M. Thomas et al., Cluster Analysis and Clinical Asthma Phenotypes, American Journal of Respiratory and Critical Care Medicine, vol.178, issue.3, pp.218-242, 2008.
DOI : 10.1164/rccm.200711-1754OC
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992366

A. Ten-brinke, P. Sterk, A. Masclee, P. Spinhoven, J. Schmidt et al., Risk factors of frequent exacerbations in difficult-to-treat asthma, European Respiratory Journal, vol.26, issue.5, pp.812-820, 2005.
DOI : 10.1183/09031936.05.00037905

C. Auffray, D. Charron, and L. Hood, Predictive, preventive, personalized and participatory medicine: back to the future, Genome Medicine, vol.2, issue.8
DOI : 10.1186/gm178

J. Bousquet, H. Schunemann, P. Bousquet, C. Bachert, G. Canonica et al., How to design and evaluate randomized controlled trials in immunotherapy for allergic rhinitis: an ARIA-GA(2) LEN statement, Allergy, 2011.