P. S. Aisen, K. L. Davis, J. D. Berg, K. Schafer, K. Campbell et al., A randomized controlled trial of prednisone in Alzheimer's disease, Neurology, vol.54, issue.3, pp.588-593, 2000.
DOI : 10.1212/WNL.54.3.588

. American-psychiatric-association, Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) American Psychiatric Association, 1994.

S. Artero, M. L. Ancelin, F. Portet, A. Dupuy, C. Berr et al., Risk profiles for mild cognitive impairment and progression to dementia are gender specific, Journal of Neurology, Neurosurgery & Psychiatry, vol.79, issue.9, pp.979-984, 2008.
DOI : 10.1136/jnnp.2007.136903
URL : https://hal.archives-ouvertes.fr/inserm-00294905

J. K. Belanoff, K. Gross, A. Yager, and A. F. Schatzberg, Corticosteroids and cognition, Journal of Psychiatric Research, vol.35, issue.3, pp.127-145, 2001.
DOI : 10.1016/S0022-3956(01)00018-8

I. Beluche, I. Carriere, K. Ritchie, and M. L. Ancelin, A prospective study of diurnal cortisol and cognitive function in community-dwelling elderly people, Psychological Medicine, vol.48, issue.06, pp.1039-1049, 2010.
DOI : 10.1192/bjp.123.4.467
URL : https://hal.archives-ouvertes.fr/inserm-00489050

A. Benton, Manuel pour l'application du test de rétention visuelle. Applications cliniques et expérimentales. Paris: Centre de Psychologie Appliquée, 1965.

R. L. Buckner, Memory and Executive Function in Aging and AD, Neuron, vol.44, issue.1, pp.195-208, 2004.
DOI : 10.1016/j.neuron.2004.09.006

D. Commenges, L. Letenneur, P. Joly, A. Alioum, and J. F. Dartigues, Modelling agespecific risk: application to dementia, Stat Med, vol.17, 1973.

C. D. Conrad and H. A. Bimonte-nelson, Impact of the Hypothalamic???pituitary???adrenal/gonadal Axes on Trajectory of Age-Related Cognitive Decline, Prog Brain Res, vol.182, pp.31-76, 2010.
DOI : 10.1016/S0079-6123(10)82002-3

T. Hedden and J. D. Gabrieli, Insights into the ageing mind: a view from cognitive neuroscience, Nature Reviews Neuroscience, vol.5, issue.2, pp.87-96, 2004.
DOI : 10.1038/nrn1323

S. N. Hilmer, A. J. Mclachlan, L. Couteur, and D. G. , Clinical pharmacology in the geriatric patient, Fundamental & Clinical Pharmacology, vol.60, issue.3, pp.217-230, 2007.
DOI : 10.1177/0272989X05280558

B. Isaacs and A. T. Kennie, The Set Test as an Aid to the Detection of Dementia in Old People, The British Journal of Psychiatry, vol.123, issue.4, 1973.
DOI : 10.1192/bjp.123.4.467

H. Jacqmin-gadda, C. Fabrigoule, D. Commenges, and J. F. Dartigues, A 5-Year Longitudinal Study of the Mini-Mental State Examination in Normal Aging, American Journal of Epidemiology, vol.145, issue.6, pp.498-506, 1997.
DOI : 10.1093/oxfordjournals.aje.a009137

P. A. Keenan, M. W. Jacobson, R. M. Soleymani, M. D. Mayes, M. E. Stress et al., The effect on memory of chronic prednisone treatment in patients with systemic disease, Neurology, vol.47, issue.6, pp.1396-1402, 1996.
DOI : 10.1212/WNL.47.6.1396

C. Kirschbaum, O. T. Wolf, M. May, W. Wippich, and D. H. Hellhammer, Stress- and treatment-induced elevations of cortisol levels associated with impaired declarative memory in healthy adults, Life Sciences, vol.58, issue.17, pp.1475-1483, 1996.
DOI : 10.1016/0024-3205(96)00118-X

B. M. Kudielka, A. Buske-kirschbaum, D. H. Hellhammer, and C. Kirschbaum, HPA axis responses to laboratory psychosocial stress in healthy elderly adults, younger adults, and children: impact of age and gender, Psychoneuroendocrinology, vol.29, issue.1, pp.83-98, 2004.
DOI : 10.1016/S0306-4530(02)00146-4

R. Kumsta, S. Entringer, J. W. Koper, E. F. Van-rossum, D. H. Hellhammer et al., Sex Specific Associations between Common Glucocorticoid Receptor Gene Variants and Hypothalamus-Pituitary-Adrenal Axis Responses to Psychosocial Stress, Biological Psychiatry, vol.62, issue.8, pp.863-869, 2007.
DOI : 10.1016/j.biopsych.2007.04.013

B. K. Lee, T. A. Glass, G. S. Wand, M. J. Mcatee, K. Bandeen-roche et al., Apolipoprotein E Genotype, Cortisol, and Cognitive Function in Community-Dwelling Older Adults, American Journal of Psychiatry, vol.165, issue.11, pp.1456-1464, 2008.
DOI : 10.1176/appi.ajp.2008.07091532

D. A. Lewis and R. E. Smith, Steroid-induced psychiatric syndromes, Journal of Affective Disorders, vol.5, issue.4, pp.319-332, 1983.
DOI : 10.1016/0165-0327(83)90022-8

G. Li, M. M. Cherrier, D. W. Tsuang, E. C. Petrie, E. A. Colasurdo et al., Salivary cortisol and memory function in human aging, Neurobiology of Aging, vol.27, issue.11, pp.1705-1714, 2006.
DOI : 10.1016/j.neurobiolaging.2005.09.031

S. J. Lupien, F. Maheu, M. Tu, A. Fiocco, and T. E. Schramek, The effects of stress and stress hormones on human cognition: Implications for the field of brain and cognition, Brain and Cognition, vol.65, issue.3, pp.209-237, 2007.
DOI : 10.1016/j.bandc.2007.02.007

C. G. Lyketsos, J. C. Breitner, R. C. Green, B. K. Martin, C. Meinert et al., Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial, Neurology, vol.68, pp.1800-1808, 2007.

B. K. Martin, C. Szekely, J. Brandt, S. Piantadosi, J. C. Breitner et al., Cognitive function over time in the Alzheimer's Disease Antiinflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib, Arch Neurol, vol.65, pp.896-905, 2008.

M. Molimard, P. O. Girodet, C. Pollet, A. Fourrier-reglat, A. Daveluy et al., Inhaled Corticosteroids and Adrenal Insufficiency, Drug Safety, vol.31, issue.9, pp.769-774, 2008.
DOI : 10.2165/00002018-200831090-00005

J. W. Newcomer, G. Selke, A. K. Melson, T. Hershey, S. Craft et al., Decreased Memory Performance in Healthy Humans Induced by Stress-Level Cortisol Treatment, Archives of General Psychiatry, vol.56, issue.6, pp.527-533, 1999.
DOI : 10.1001/archpsyc.56.6.527

P. Noize, F. Bazin, C. Dufouil, N. Lechevallier-michel, M. L. Ancelin et al., Comparison of health insurance claims and patient interviews in assessing drug use: data from the Three-City (3C) Study, Pharmacoepidemiology and Drug Safety, vol.47, issue.4, pp.310-319, 2009.
DOI : 10.1159/000072920

O. 'hara, R. Schroder, C. M. Mahadevan, R. Schatzberg, A. F. Lindley et al., Serotonin transporter polymorphism, memory and hippocampal volume in the elderly: association and interaction with cortisol, Molecular Psychiatry, vol.11, issue.6, pp.544-555, 2007.
DOI : 10.1038/sj.mp.4001978

C. Otte, S. Hart, T. C. Neylan, C. R. Marmar, K. Yaffe et al., A meta-analysis of cortisol response to challenge in human aging: importance of gender, Psychoneuroendocrinology, vol.30, issue.1, pp.80-91, 2005.
DOI : 10.1016/j.psyneuen.2004.06.002

J. C. Pruessner, K. Dedovic, M. Pruessner, C. Lord, C. Buss et al., Stress regulation in the central nervous system: evidence from structural and functional neuroimaging studies in human populations - 2008 Curt Richter Award Winner, Psychoneuroendocrinology, vol.35, issue.1, pp.179-191, 2010.
DOI : 10.1016/j.psyneuen.2009.02.016

L. Radloff, The CES-D Scale: A Self-Report Depression Scale for Research in the General Population, Applied Psychological Measurement, vol.1, issue.3, pp.385-401, 1977.
DOI : 10.1177/014662167700100306

S. Rasmuson, B. Nasman, K. Carlstrom, and T. Olsson, Increased Levels of Adrenocortical and Gonadal Hormones in Mild to Moderate Alzheimer???s Disease, Dementia and Geriatric Cognitive Disorders, vol.13, issue.2, pp.74-79, 2002.
DOI : 10.1159/000048637

R. Reitan, VALIDITY OF THE TRAIL MAKING TEST AS AN INDICATOR OF ORGANIC BRAIN DAMAGE, Perceptual and Motor Skills, vol.19, issue.3, pp.271-276, 1965.
DOI : 10.2466/pms.1958.8.3.271

K. Ritchie, I. Carriere, A. De-mendonca, F. Portet, J. F. Dartigues et al., The neuroprotective effects of caffeine: A prospective population study (the Three City Study), Neurology, vol.69, issue.6, pp.536-545, 2007.
DOI : 10.1212/01.wnl.0000266670.35219.0c
URL : https://hal.archives-ouvertes.fr/inserm-00168786

K. Ritchie, I. Carriere, C. W. Ritchie, C. Berr, S. Artero et al., Designing prevention programs to reduce dementia incidence. A prospective study of modifiable risk factors, Br Med J, on line first, vol.341, p.3885, 2010.

O. Sacks and M. Shulman, Steroid dementia: An overlooked diagnosis?, Neurology, vol.64, issue.4, pp.707-709, 2005.
DOI : 10.1212/01.WNL.0000151977.18440.C3

M. D. Sauro, R. S. Jorgensen, and C. T. Pedlow, Stress, Glucocorticoids, and Memory: A Meta-analytic Review, Stress, vol.115, issue.4, pp.235-245, 2003.
DOI : 10.1038/29542

T. E. Seeman, B. S. Mcewen, B. H. Singer, M. S. Albert, and J. W. Rowe, Increase in Urinary Cortisol Excretion and Memory Declines: MacArthur Studies of Successful Aging, Journal of Clinical Endocrinology & Metabolism, vol.82, issue.8, pp.2458-2465, 1997.
DOI : 10.1210/jc.82.8.2458

C. A. Szekely, R. C. Green, J. C. Breitner, T. Ostbye, A. S. Beiser et al., No advantage of A??42-lowering NSAIDs for prevention of Alzheimer dementia in six pooled cohort studies, Neurology, vol.70, issue.24, pp.2291-2298, 2008.
DOI : 10.1212/01.wnl.0000313933.17796.f6

C. A. Szekely, J. E. Thorne, P. P. Zandi, M. Ek, E. Messias et al., Nonsteroidal Anti-Inflammatory Drugs for the Prevention of Alzheimer???s Disease: A Systematic Review, Neuroepidemiology, vol.23, issue.4, pp.159-169, 2004.
DOI : 10.1159/000078501

C. A. Szekely and P. P. Zandi, Non-Steroidal Anti-Inflammatory Drugs and Alzheimers Disease: The Epidemiological Evidence, CNS & Neurological Disorders - Drug Targets, vol.9, issue.2, pp.132-139, 2010.
DOI : 10.2174/187152710791012026

L. J. Thal, S. H. Ferris, L. Kirby, G. A. Block, C. R. Lines et al., A Randomized, Double-Blind, Study of Rofecoxib in Patients with Mild Cognitive Impairment, Neuropsychopharmacology, vol.10, issue.6, pp.1204-1215, 2005.
DOI : 10.1038/sj.npp.1300690

3. The and . Group, Vascular factors and risk of dementia: Design of the three city study and baseline characteristics of the study population, Neuroepidemiology, vol.22, pp.316-325, 2003.

H. Umegaki, H. Ikari, H. Nakahata, H. Endo, Y. Suzuki et al., Plasma cortisol levels in elderly female subjects with Alzheimer???s disease: a cross-sectional and longitudinal study, Brain Research, vol.881, issue.2, pp.241-243, 2000.
DOI : 10.1016/S0006-8993(00)02847-X

S. C. Vlad, D. R. Miller, N. W. Kowall, and D. T. Felson, Protective effects of NSAIDs on the development of Alzheimer disease, Neurology, vol.70, issue.19, pp.1672-1677, 2008.
DOI : 10.1212/01.wnl.0000311269.57716.63

J. Wang, M. Korczykowski, H. Rao, Y. Fan, J. Pluta et al., Gender difference in neural response to psychological stress, Gender Difference in Neural Response to Psychological Stress, pp.227-239, 2007.
DOI : 10.1093/scan/nsm018

O. M. Wolkowitz, H. Burke, E. S. Epel, and V. I. Reus, Glucocorticoids, Annals of the New York Academy of Sciences, vol.13, issue.Suppl, pp.19-40, 2009.
DOI : 10.1111/j.1749-6632.2009.04980.x

O. M. Wolkowitz, S. J. Lupien, and E. D. Bigler, The ???Steroid Dementia Syndrome???: A Possible Model of Human Glucocorticoid Neurotoxicity, Neurocase, vol.147, issue.3, pp.189-200, 2007.
DOI : 10.1038/sj.mp.4000967

T. Wyss-coray and L. Mucke, Inflammation in Neurodegenerative Disease???A Double-Edged Sword, Neuron, vol.35, issue.3, pp.419-432, 2002.
DOI : 10.1016/S0896-6273(02)00794-8

A. H. Young, B. J. Sahakian, T. W. Robbins, and P. J. Cowen, The effects of chronic administration of hydrocortisone on cognitive function in normal male volunteers, Psychopharmacology, vol.145, issue.3, pp.260-266, 1999.
DOI : 10.1007/s002130051057