W. Abraham and M. Bear, Metaplasticity: the plasticity of synaptic plasticity, Trends in Neurosciences, vol.19, pp.126-156, 1996.

A. Ali, K. Hoeflich, and J. Woodgett, Glycogen synthase kinase-3: properties, functions, and regulation, Chem Rev, vol.101, pp.2527-2567, 2001.

G. Alvarez, J. Munoz-montano, J. Satrustegui, J. Avila, E. Bogonez et al., Regulation of tau phosphorylation and protection against beta-amyloidinduced neurodegeneration by lithium. Possible implications for Alzheimer's disease, Bipolar Disord, vol.4, pp.153-65, 2002.

B. Anderton, Alzheimer's disease: clues from flies and worms, Curr Biol, vol.9, pp.106-115, 1999.

M. Andreasen, J. Lambert, and M. Jensen, Effects of new non-N-methyl-Daspartate antagonists on synaptic transmission in the in vitro rat hippocampus, J Physiol, vol.414, pp.317-353, 1989.

J. Avila, J. Lucas, M. Perez, and F. Hernandez, Role of tau protein in both physiological and pathological conditions, Physiol Rev, vol.84, pp.361-84, 2004.

Z. Bashir, S. Alford, S. Davies, A. Randall, and G. Collingridge, Long-term potentiation of NMDA receptor-mediated synaptic transmission in the hippocampus, Nature, vol.349, p.156, 1991.

Z. Bashir, D. Jane, D. Sunter, J. Watkins, and G. Collingridge, Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus, European Journal of Pharmacology, vol.239, p.265, 1993.

M. Bear and W. Abraham, Long-term depression in hippocampus, Annual Review of Neuroscience, vol.19, pp.437-462, 1996.

C. Beasley, D. Cotter, N. Khan, C. Pollard, P. Sheppard et al., Glycogen synthase kinase-3beta immunoreactivity is reduced in the prefrontal cortex in schizophrenia, Neurosci Lett, vol.302, pp.117-137, 2001.

M. Beneyto, L. Kristiansen, A. Oni-orinsan, R. Mccullumsmith, and J. Meador-woodriff, Abnormal glutamate receptor expression in the medial Temporal Lobe in schizophrenia and mood disorders, Neuropsychopharmacology, vol.32, pp.1888-1902, 2007.

R. Bhat, B. Haeberlein, S. Avila, and J. , Glycogen synthase kinase 3: a drug target for CNS therapies, J Neurochem, vol.89, pp.1313-1320, 2004.

T. Bliss and G. Collingridge, A synaptic model of memory: long-term potentiation in the hippocampus, Nature, vol.361, pp.31-39, 1993.

T. Bliss, G. Collingridge, R. Morris, P. Andersen, R. G. Morris et al., Synaptic plasticity in the hippocampus, The Hippocampus Book, pp.343-474, 2007.

V. Bolshakov and S. Siegelbaum, Postsynaptic induction and presynaptic expression of hippocampal long-term depression, Science, vol.264, pp.1148-52, 1994.

Z. Bortolotto, V. Clarke, C. Delany, M. Parry, I. Smolders et al., Kainate receptors are involved in synaptic plasticity, Nature, vol.402, p.297, 1999.
URL : https://hal.archives-ouvertes.fr/hal-00659444

Z. Bortolotto, S. Fitzjohn, and G. Collingridge, Roles of metabotropic glutamate receptors in LTP and LTD in the hippocampus, Current Opinion in Neurobiology, vol.9, p.299, 1999.

C. Busceti, F. Biagioni, E. Aronica, B. Riozzi, M. Storto et al., Induction of the Wnt inhibitor, Dickkopf-1, is associated with neurodegeneration related to temporal lobe epilepsy, Epilepsia, vol.48, pp.694-705, 2007.

P. Chen, Z. Gu, W. Liu, and Z. Yan, Glycogen synthase kinase 3 regulates Nmethyl-D-aspartate receptor channel trafficking and function in cortical neurons, Mol Pharmacol, vol.72, pp.40-51, 2007.

G. Collingridge, S. Kehl, and H. Mclennan, Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus, Journal of Physiology, vol.334, pp.33-46, 1983.

S. Davies and G. Collingridge, Role of excitatory amino acid receptors in synaptic transmission in area CA1 of rat hippocampus, Proc.R.Soc.Lond B Biol.Sci, vol.236, p.373, 1989.

B. Doble and J. Woodgett, GSK-3: tricks of the trade for a multi-tasking kinase, J Cell Sci, vol.116, pp.1175-86, 2003.

J. Du, K. Suzuki, Y. Wei, Y. Wang, R. Blumenthal et al., The anticonvulsants lamotrigine, riluzole, and valproate differentially regulate AMPA receptor membrane localization: relationship to clinical effects in mood disorders, Neuropsychopharmacology, vol.32, pp.793-802, 2007.

S. Dudek and M. Bear, Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade, Proceedings of the National Academy of Science U S A, p.4363, 1992.

H. Eldar-finkelman, Glycogen synthase kinase 3: an emerging therapeutic target, Trends Mol Med, vol.8, pp.126-158, 2002.

N. Embi, D. Rylatt, and P. Cohen, Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase, Eur J Biochem, vol.107, pp.519-546, 1980.

S. Fitzjohn, Z. Bortolotto, M. Palmer, A. Doherty, P. Ornstein et al., The potent mGlu receptor antagonist LY341495 identifies roles for both cloned and novel mGlu receptors in hippocampal synaptic plasticity, Neuropharmacology, vol.37, p.1445, 1998.

S. Frame and P. Cohen, GSK3 takes centre stage more than 20 years after its discovery, Biochem J, vol.359, pp.1-16, 2001.

S. Fujii, K. Saito, H. Miyakawa, K. Ito, and H. Kato, Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices, Brain Res, vol.555, pp.112-134, 1991.

N. Goode, K. Hughes, J. Woodgett, and P. Parker, Differential regulation of glycogen synthase kinase-3 beta by protein kinase C isotypes, Journal of Biological Chemistry, vol.267, pp.16878-82, 1992.

T. Gould and H. Manji, Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs, Neuropsychopharmacology, vol.30, pp.1223-1260, 2005.

G. Crabtree, L-type calcium channels and GSK-3 regulate the activity of NF- ATc4 in hippocampal neurons, Nature, vol.401, pp.703-711, 1999.

C. Grimes and R. Jope, The multifaceted roles of glycogen synthase kinase 3beta in cellular signaling, Prog Neurobiol, vol.65, pp.391-426, 2001.

D. Hanger, K. Hughes, J. Woodgett, J. Brion, and B. Anderton, Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase, Neurosci Lett, vol.147, pp.58-62, 1992.

E. Harris and C. Cotman, Long-term potentiation of guinea pig mossy fiber responses is not blocked by N-methyl D-aspartate antagonists, Neurosci Lett, vol.70, pp.132-139, 1986.

A. Harwood, Lithium and bipolar mood disorder: the inositol-depletion hypothesis revisited, Molecular Psychiatry, vol.10, pp.117-143, 2005.

F. Hernandez, J. Borrell, C. Guaza, J. Avila, and J. Lucas, Spatial learning deficit in transgenic mice that conditionally over-express GSK-3beta in the brain but do not form tau filaments, J Neurochem, vol.83, pp.1529-1562, 2002.

C. Hooper, V. Markevich, F. Plattner, R. Killick, E. Schofield et al., Glycogen synthase kinase-3 inhibition is integral to long-term potentiation, Eur J Neurosci, vol.25, pp.81-87, 2007.

K. Hughes, E. Nikolakaki, S. Plyte, N. Totty, and J. Woodgett, Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation, EMBO Journal, vol.12, pp.803-811, 1993.

H. Jiang, W. Guo, X. Liang, and Y. Rao, Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK- 3beta and its upstream regulators, Cell, vol.120, pp.123-158, 2005.

F. Kirschenbaum, S. Hsu, B. Cordell, and J. Mccarthy, Glycogen synthase kinase-3beta regulates presenilin 1 C-terminal fragment levels, J Biol Chem, vol.276, pp.30701-30708, 2001.

P. Klein and D. Melton, A molecular mechanism for the effect of lithium on development, Proc Natl Acad Sci U S A, vol.93, pp.8455-8464, 1996.

S. Koh, Y. Kim, H. Kim, S. Hwang, C. Lee et al., Inhibition of glycogen synthase kinase-3 suppresses the onset of symptoms and disease progression of G93A-SOD1 mouse model of ALS, Experimental Neurology, vol.205, pp.336-382, 2007.

N. Kozlovsky, R. Belmaker, and G. Agam, GSK-3 and the neurodevelopmental hypothesis of schizophrenia, Eur Neuropsychopharmacol, vol.12, pp.13-25, 2002.

Y. Lee, M. Seo, Y. Kim, S. Kim, U. Kang et al., Membrane depolarization induces the undulating phosphorylation/dephosphorylation of glycogen synthase kinase 3beta, and this dephosphorylation involves protein phosphatases 2A and 2B in SH-SY5Y human neuroblastoma cells, J Biol Chem, vol.280, pp.22044-52, 2005.

K. Leroy and J. Brion, Developmental expression and localization of glycogen synthase kinase-3beta in rat brain, J Chem Neuroanat, vol.16, pp.279-93, 1999.

H. Man, Q. Wang, W. Lu, W. Ju, G. Ahmadian et al., Activation of PI3-kinase is required for AMPA receptor insertion during LTP of mEPSCs in cultured hippocampal neurons, Neuron, vol.38, pp.611-635, 2003.

D. Manahan-vaughan, A. Kulla, and J. Frey, Requirement of translation but not transcription for the maintenance of long-term depression in the CA1 region of freely moving rats, Journal of Neuroscience, vol.20, pp.8572-8578, 2000.

G. Morfini, G. Szebenyi, H. Brown, H. Pant, G. Pigino et al., A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons, Embo J, vol.23, pp.2235-2280, 2004.

R. Mulkey, S. Endo, S. Shenolikar, and R. Malenka, Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression, Nature, vol.369, pp.486-494, 1994.

R. Mulkey, C. Herron, and R. Malenka, An essential role for protein phosphatases in hippocampal long-term depression, Science, vol.261, pp.1051-1056, 1993.

R. Mulkey and R. Malenka, Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus, Neuron, vol.9, pp.967-975, 1992.

S. Peineau, C. Taghibiglou, C. Bradley, T. Wong, L. Liu et al., LTP inhibits LTD in the hippocampus via regulation of GSK3beta, Neuron, vol.53, pp.703-720, 2007.
URL : https://hal.archives-ouvertes.fr/inserm-00776885

F. Plattner, M. Angelo, and K. Giese, The roles of cyclin-dependent kinase 5 and glycogen synthase kinase 3 in tau hyperphosphorylation, Journal of Biological Chemistry, vol.281, pp.25457-65, 2006.

W. Ryves and A. Harwood, Lithium inhibits glycogen synthase kinase-3 by competition for magnesium, Biochemical & Biophysical Research Communications, vol.280, pp.720-725, 2001.

E. Szatmari, A. Habas, P. Yang, J. Zheng, T. Hagg et al., A positive feedback loop between glycogen synthase kinase 3beta and protein phosphatase 1 after stimulation of NR2B NMDA receptors in forebrain neurons, J Biol Chem, vol.280, pp.37526-37561, 2005.

M. Takahashi, K. Tomizawa, R. Kato, K. Sato, T. Uchida et al., Localization and developmental changes of tau protein kinase I/glycogen synthase kinase-3 beta in rat brain, J Neurochem, vol.63, pp.245-55, 1994.

K. Watase, J. Gatchel, Y. Sun, E. Emamian, R. Atkinson et al., Lithium therapy improves neurological function and hippocampal dendritic arborization in a spinocerebellar ataxia type 1 mouse model, p.182, 2007.

N. Wood and A. Morton, Chronic lithium chloride treatment has variable effects on motor behaviour and survival of mice transgenic for the Huntington's disease mutation, Brain Research Bulletin, vol.61, pp.375-83, 2003.

J. Woodgett, Molecular cloning and expression of glycogen synthase kinase- 3/factor A, Embo J, vol.9, pp.2431-2439, 1990.