GeVaDSs - decision support system for novel Genetic Vaccine development process. - Archive ouverte HAL Access content directly
Journal Articles BMC Bioinformatics Year : 2012

GeVaDSs - decision support system for novel Genetic Vaccine development process.

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Abstract

UNLABELLED: ABSTRACT: BACKGROUND: The lack of a uniform way for qualitative and quantitative evaluation of vaccine candidates under development led us to set up a standardized scheme for vaccine efficacy and safety evaluation. We developed and implemented molecular and immunology methods, and designed support tools for immunization data storage and analyses. Such collection can create a unique opportunity for immunologists to analyse data delivered from their laboratories. RESULTS: We designed and implemented GeVaDSs (Genetic Vaccine Decision Support system) an interactive system for efficient storage, integration, retrieval and representation of data. Moreover, GeVaDSs allows for relevant association and interpretation of data, and thus for knowledge-based generation of testable hypotheses of vaccine responses. CONCLUSIONS: GeVaDSs has been tested by several laboratories in Europe, and proved its usefulness in vaccine analysis. Case study of its application is presented in the additional files. The system is available at: http://gevads.cs.put.poznan.pl/preview/(login: viewer, password: password).
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Dates and versions

inserm-00769034 , version 1 (27-12-2012)

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Jacek Blazewicz, Marcin Borowski, Wahiba Chaara, Pawel Kedziora, David Klatzmann, et al.. GeVaDSs - decision support system for novel Genetic Vaccine development process.. BMC Bioinformatics, 2012, 13 (1), pp.91. ⟨10.1186/1471-2105-13-91⟩. ⟨inserm-00769034⟩
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