Critical Amino Acid Residues Determine the Binding Affinity and the Ca2+ Release Efficacy of Maurocalcine in Skeletal Muscle Cells, Journal of Biological Chemistry, vol.278, issue.39, pp.37822-37831, 2003. ,
DOI : 10.1074/jbc.M305798200
Efficient induction of apoptosis by doxorubicin coupled to cell-penetrating peptides compared to unconjugated doxorubicin in the human breast cancer cell line MDA-MB 231, Cancer Letters, vol.285, issue.1, pp.28-38, 2009. ,
DOI : 10.1016/j.canlet.2009.04.044
URL : https://hal.archives-ouvertes.fr/inserm-00410230
Conjugation of doxorubicin to cell penetrating peptides sensitizes human breast MDA-MB 231 cancer cells to endogenous TRAIL-induced apoptosis, Apoptosis, vol.180, issue.3, pp.1352-1365, 2009. ,
DOI : 10.1007/s10495-009-0397-8
URL : https://hal.archives-ouvertes.fr/inserm-00515338
Cytotoxicity, intracellular distribution and uptake of doxorubicin and doxorubicin coupled to cell-penetrating peptides in different cell lines: A comparative study, Biochemical and Biophysical Research Communications, vol.391, issue.1, pp.419-425, 2010. ,
DOI : 10.1016/j.bbrc.2009.11.073
URL : https://hal.archives-ouvertes.fr/inserm-00587567
Maurocalcine as a Non Toxic Drug Carrier Overcomes Doxorubicin Resistance in the Cancer Cell Line MDA-MB 231, Pharmaceutical Research, vol.106, issue.Pt 4, pp.836-845, 2009. ,
DOI : 10.1007/s11095-008-9782-1
URL : https://hal.archives-ouvertes.fr/inserm-00356481
Biochim Biophys Acta 1768, J Biol Chem Merrifield, R. B. Adv Enzymol Relat Areas Mol Biol J Biol Chem J Cell Biol, vol.285, issue.109, 1969. ,
1119?1131 FOOTNOTES This work was supported by grants from Technology pour la Santé (Program TIMOMA2 of the Commissariat à l'Energie Atomique) and from Agence Nationale pour la Recherche PNANO (Programs SYNERGIE and NanoFret) Mass spectrometry analyses were performed by the Centre d'Investigation Clinique of Grenoble under the heading of Dr. Michel Sève. The abbreviations used are: CD: Circular Dichroism; CPP: Cell Penetrating Peptide; DMF: dimethyformamide; FACS: Fluorescence?Activated Cell Sorting; HPLC: high?performance liquid chromatography; MCa: Maurocalcine; NMP: N?methyl?pyrrolidone; RS: Sarcoplasmic reticulum Ryanodine Receptor TFA: trifluoroacetic acid, J Cell Biol, vol.158, p.2, 2002. ,